Tag: Target

  • Immunization is the best protection against tick-borne encephalitis

    Immunization is the best protection against tick-borne encephalitis

    immunization-is-the-best-protection-against-tick-borneIn a new position paper, published in the Weekly
    Epidemiological Record today, WHO recommends vaccination against
    tick-borne encephalitis in people of all ages where the disease is
    highly endemic. Where the prevaccination incidence of the disease is
    moderate or low or is limited to particular geographical locations or
    certain outdoor activities, immunization should target individuals in
    the most severely affected groups. People travelling from non-endemic
    areas to endemic areas should be offered vaccination if their visits
    will include extensive outdoor activities.

    Since the incidence of tick-borne encephalitis may vary
    considerably between and even within geographical regions, public
    immunization strategies should be based on risk assessments conducted at
    country, regional or district level, and should be appropriate to the
    local endemic situation.

    Immunization offers the most effective protection against
    tick-borne encephalitis. Currently, there are four widely used vaccines
    of assured quality: FSME-Immun and Encepur, manufactured in Austria and
    Germany respectively, and TBE-Moscow and EnceVir, manufactured in the
    Russian Federation. The four vaccines are considered to be safe and
    efficacious.

    Tick-borne encephalitis virus is an important cause of viral
    infections of the central nervous system in eastern, central and
    northern European countries, and in northern China, Mongolia, and the
    Russian Federation.

    Approximately 10 000–12 000 clinical cases of tick-borne
    encephalitis are reported each year, but this figure is believed to be
    significantly lower than the actual total. Most infections with the
    virus result from tick bites acquired during outdoor activities in
    forested areas.

    Immunization is the best protection against tick-borne encephalitis
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    https://www.who.int/news-room/detail/19-02-2020-immunization-is-the-best-protection-against-tick-borne-encephalitis

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  • WHO and FIND formalize strategic collaboration to drive universal access to essential diagnostics

    Geneva, Switzerland – 10 February 2020 – The World Health Organization (WHO) and the Foundation for Innovative New Diagnostics (FIND) announced today that a memorandum of understanding has been signed by the two organizations to formalize a strategic collaboration that will strengthen diagnosis in resource-poor countries by closing major diagnostic gaps at country level and bolstering disease surveillance that will inform public health initiatives and enhance outbreak preparedness and response.

    “This collaboration is an inspiring development that will take us a long way towards ensuring access to diagnostics to all who need them,” said Dr Tedros Adhanom Ghebreyesus, Director-General of the World Health Organization. “Global health challenges such as the ongoing novel coronavirus (2019-nCoV) outbreak demonstrates that without these essential elements of health systems, we cannot hope to promote health, keep the world safe, and serve the vulnerable. I look forward to working closely with FIND to determine what countries need and to forge a path to deliver these innovations so that no one is left behind.”

    Diagnosis is a driver of patient, financial and health systems impact, and a critical enabler of universal health coverage, but it is also the weakest link in the care cascade. This is especially true in primary healthcare settings in low- and middle-income countries. A unique and unprecedented opportunity exists to expand the role and impact of diagnostics to fully realize their potential to address major health security threats and evolving disease burdens through technological and digital advances.

    FIND has been an active partner with WHO since 2008 and a WHO Collaborating Centre since 2014, acting in the areas of laboratory strengthening and diagnostic technology evaluation. This expanded collaboration will put in place the building blocks necessary to enable transformative change in a move toward a country-led diagnostics alliance. Initial workstreams will focus on demand-driven access to essential diagnostics and the development of national Essential Diagnostics Lists, alongside collection of data that assist the scale up of diagnostics to support low- and middle-income countries on their paths to universal health coverage.

    “Each and every person has the right to a quality, timely diagnosis,” said Catharina Boehme, CEO of FIND. “Comprehensive diagnostic services underpin functional and efficient health systems not only to manage day-to-day healthcare needs, but also to ensure new disease outbreaks can be spotted and contained quickly. Working closely with WHO as part of a country-led alliance, we will strive to ensure that low- and middle-income countries have what they need to develop their own comprehensive, data-driven diagnostic strategies that enable universal health coverage and empower disease surveillance. Our ambition is that all patients, providers and decision-makers have access to the diagnostic solutions needed for optimal health outcomes.”

    The strategic collaboration agreement will initially run for a period of 5 years, until 2025.

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    About FIND

    FIND is a global non-profit organization that drives innovation in the development and delivery of diagnostics to combat major diseases affecting the world’s poorest populations. Our work bridges R&D to access, overcoming scientific barriers to technology development; generating evidence for regulators and policy-makers; addressing market failures; and enabling accelerated uptake and access to diagnostics in low- and middle-income countries (LMICs). Since 2003, we have been instrumental in the development of 24 new diagnostic tools used in 150 LMICs. Over 50 million FIND-supported products have been provided to our target markets since the start of 2015. A WHO Collaborating Centre, we work with more than 200 academic, industry, governmental, and civil society partners worldwide, on over 70 active projects that cross six priority disease areas. FIND is committed to a future in which diagnostics underpin treatment decisions and provide the foundation for disease surveillance, control and prevention. For more information, please visit www.finddx.org

     

    About WHO

    The World Health Organization is the directing and coordinating authority for health within the United Nations system. It is responsible for providing leadership on global health matters, shaping the health research agenda, setting norms and standards, articulating evidence-based policy options, providing technical support to countries and monitoring and assessing health trends. WHO is committed to the enjoyment of the highest attainable standard of health as one of the fundamental rights of every human being without distinction of race, religion, political belief, economic or social condition. WHO’s current global programme of work sets out three interconnected strategic priorities: ensuring healthy lives and well-being for all at all ages; achieving universal health coverage; and addressing health emergencies and promoting healthier populations. These priorities are linked to three ambitious targets, the “triple billion”: one billion more people to benefit from universal health coverage; one billion more people better protected from health emergencies; and one billion more people enjoying better health and well-being.

     

    Read More
    https://www.who.int/news-room/detail/10-02-2020-who-and-find-formalize-strategic-collaboration-to-drive-universal-access-to-essential-diagnostics

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  • Rap1, a potential new target to treat obesity

    Rap1, a potential new target to treat obesity

    cientists at Baylor College of Medicine, the National Institutes of Health and Virginia Tech Carilion Research Institute have discovered a new mechanism in the mouse brain that regulates obesity. The study, which appears in Cell Reports today, shows that this new mechanism can potentially be targeted to treat obesity.

    “It’s well known that the brain is involved in the development of obesity, but how a high-fat diet changes the brain so it triggers the accumulation of body fat is still unclear,” said senior author Dr. Makoto Fukuda, assistant professor of pediatrics at Baylor and the USDA/ARS Children’s Nutrition Research Center at Baylor and Texas Children’s Hospital.

    Fukuda and colleagues studied the mouse Rap1 gene, which is expressed in a variety of tissues, including the brain where it is involved in functions such as memory and learning. Little was known, however, of the role brain Rap1 plays in energy balance.

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  • Intercepting enemy unmanned aircraft systems midflight

    Intercepting enemy unmanned aircraft systems midflight

    Sandia National Laboratories robotics experts are working on a way to intercept enemy unmanned aircraft systems midflight. They successfully tested their concept indoors with a swarm of four unmanned aircraft systems that flew in unison, each carrying one corner of a net. Acting as a team, they intercepted the flying target, trapped it in air like an insect caught in a web and safely lowered it to the ground.

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  • How to Write Technically for the Lay Person

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    While you are writing a book or for a specific magazine or article site, you must be using flowery language using striking words, long sentences, phrases or idioms. In short, you need all those elements that will make the text more catchy and will hook the readers! However, that is not the case in technical writing, i.e. when you are writing for websites that are services or products based. Built using advanced web development frameworks, they need to be produced with clean and simple content that is conversational to the buyers. Specifically, the web content must be representative of the services and the company. But, why called technical writing? A good content on the websites plays a great part in SEO and content marketing. It helps in getting the backlinks and scale up in position of the websites in the search engines to get more visitors.

    So, the next time you are preparing content for a high-end website or online application for your business, keep these tips in mind.

    #1 Know your target audience

    The first thing you need clear-off in your head is the target audience of your site. Be it a group of businessmen or corporate services clients, they are all layman! So, keep your vocabulary outright simple. Don’t use more of technical words and flowery English to make the content snappy. Instead, keep it outright simple, such that even a kid can understand what you provide from your site.

    #2 Show but don’t dictate

    Do not dictate or describe everything about your products or services to the visitors in text. Let them discover that gradually as they proceed to different pages. It makes the visitors curious and persuades them to visit more pages of your site in a session. Thus, show them what you provide, but don’t spell it.

    #3 Use simple, short sentences and active voice

    There is actually no point in over-elaborating technical stuff in the websites. Most visitors are basically skimmers and like to wrap up things quickly. So, try using shorter and simple sentences. And, also use active voice as it’s like you are directly interacting with them.

    #4 Be assertive

    Do not assume that everyone knows about your company, products or services. They don’t. But, they are coming to your site to know about it. So, write with absolute authority and command.

    #5 Avoid the jargon

    Your website is for the layman. Not only for the technically skilled ones! Be sure you are putting information that is also easily understandable by the non-specialists. Even if you need to use complex, technical or niche terms, explain them or hyperlink them to other pages that will give their basic information.

    #6 Use text to compliment the images

    While you will be putting images at every relevant point or pages on the website, create content that will perfectly compliment them. This will enhance the visuals of the site and make it more captivating for the readers.

    These explain web development just do not end with creating a great website or application. But, developers need to have some online content marketing ideas too. They have to know well what exactly can fetch a good amount of visitors to a website, besides making it design-wise attractive.

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    Source by Rob Stephen

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  • MLM Business Plan: How Can You Use One To Profit ASAP?

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    Although getting a plan together is a genuine necessity, you’ll be pleased to know it’s actually rather simple to put one together or to make a few changes to your existing plan.

    Many online marketers understand that getting a plan together is a genuine necessity, you’ll be pleased to know it’s actually rather simple to put one together or to make a few changes to your existing plan.

    Although it is easy to create an MLM business plan when you know what your goals are, creating a profitable one is a different story altogether. To create these type of plans to actually turn a profit in your business, the main focus needs to be on how effective your marketing strategy is when it comes to generating commissions and sign ups in your downline.

    There are two main ways in which you can advertise online to turn a profit:

    1) Free marketing: social networking or content marketing are king here, basically any user generated content or anywhere in which you can interact one on one with another person within your circle of friends (or associates).

    This is a fun way to incorporate marketing into your MLM business plan, but it can be time consuming and without a large amount of people following your content, you have no real leverage and therefore no immediate profit.

    2) Paid marketing: this is an obvious one, but basically anywhere you pay to post an advert. For online marketing, adverts on other people’s blogs or sending solo ads to other marketer’s email lists are the most cost effective although there are more popular paid marketing methods such as Facebook advertising.

    These get immediate and targeted traffic, but without the proper education on paid methods you will certainly break the bank before you profit. With this option, you must also understand that this is an investment and there are times when you may even lose money, especially if you promote your offer to the wrong target market.

    Finally, you must analyse what you’re spending in your business. Is the product, service or event you’re about to invest in something that can be monetised, for example what will you learn in the training you purchase that will cover the cost of your investment? Or can you become an affiliate for what you’ve just purchased and sell copies of it to earn commissions?

    In conclusion, when you’re piecing together your MLM business plan you’re going to need to take a common sense approach. Forget cutting corners to save money, make sure the focus is on providing value to your potential customers in your marketing efforts whilst making your advertising cost effective.

    Lastly, ensure that the amount of advertising you will be implementing reflect on your goals e.g. number of sales a month so that you stay consistent with both your goals and marketing to avoid getting overwhelmed in your business, especially if you’re new to the MLM industry. Now that you have a basic understanding on how to profit quickly with an effective MLM business plan, what are you going to incorporate into your plan?

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    Source by Seb Brantigan

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  • Affiliate Marketer – The Win-Win Technique

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    Affiliate marketing has turned out to be just about the most efficient way to market on the web. It is usually among the most active for anybody with a web site in order to obtain profits on the internet. Affiliate marketing is an arrangement made by a product owner and a site owner. The site manager, permits the usage of the website for the advertising of the merchant’s goods by back-linking towards the merchant’s web-site. In return, the vendor or product owner compensates the internet marketer according to all product sales produced because of the internet marketer efforts. Whenever an individual follows the URL ((Uniform Resource Locator) on the internet marketer site and proceed to made a purchase, the affiliate marketer receives a percentage. The product owner pays off the affiliate as long as a person clicks the merchandise link and buys something.

    Affiliate programs are identified as a win-win scenario for both the vendor and also the affiliate because of the pay-for-performance structure. Both parties enjoy big benefits with this technique. There are numerous rewards for the merchant. It provides them with a larger market place to promote services or products. Through their marketing efforts, the affiliate marketer will provide the goods and services the ideal visibility that maybe could not be possible with the use of traditional promotion approaches. The more online websites a vendor has access to, the larger the exposure his products will have, which more than often converts into product sales. Internet affiliate marketing is the same as possessing an army of sales agents who can carry out promotion and may only get paid in the case a client buys.

    At the same time, because an affiliate marketer relationship can be a win-win scenario, the affiliate marketer also looks forward to lots of benefits. Foremost involving these is the simplest way to produce revenues. The affiliate marketer can gain using an advertisement or back-link to the vendor’s site, which potential customers will ideally press and ultimately make a purchase. When the target individual follows the offer within the affiliate’s website, is rerouted towards the vendor’s site and usually proceeds to purchase that specific product or service. The more recommendations are made, the far more possibilities of earnings for that internet marketer.

    Affiliate programs are an exceptional way to generate income while in your own home. You’ll find practically no initial expenses. The merchandise has already been created and verified through the vendor, and the only costs you have are the ones related to finding the customers and direct them in front of the offer. Internet programs are typically exempt of cost to sign up for, so affiliate marketers don’t need to be worried about start-up fees. There are millions of products you can consider. You’ll find affiliate marketing programs available for practically any merchandise offered in the web. Certainly, you can find a service or product out there that is definitely related to your site.

    Furthermore, there is no sales knowledge required. Most programs provide outstanding assistance with regards to supplying advertising material. The simplicity of online marketing enables you to be an internet marketer at the minimum cost as well as enjoy the most convenience. You may also be able to create a profitable affiliate marketing enterprise in the comfort and ease of your home. In internet affiliate marketing, your main duty is actually to seek out potential customers and direct them to your selected offers; there is no need to concern yourself with products on hand, quality or even delivery. These, together with customer support are the responsibilities of the product owner.

    Due to the possibilities on the world-wide-web, it is simple to find a large number of prospective buyers. You are able to accentuate your strategy by applying extra competitive and effective techniques including viral marketing and videos. By bringing in much more prospective buyers, you’ll realize a big increase in your possibility to generate income. Another advantage of an internet marketer is definitely the small monetary risk involved. When the item you happen to be promoting is just not creating wealth you’ll be able to dump it and select a different one. There aren’t any long-term binding agreements braiding you to products and solutions that are certainly not creating sufficient revenues.

    Consider the very best advantage of becoming an internet marketer as the unique chance to improve your revenues and the fact that you may earn profits even when you use internet affiliate marketing only as a part-time business. With your personal affiliate enterprise, you can generate easily some extra income, despite the reality that you need to apply hard work and made use of your thoughts to maximize your possible earnings. Without a doubt, affiliate marketing and advertising is among the most basic and most successful work at home opportunities on the internet today.

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    Source by Ruth Celeste Lee

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  • How Nootropics Make You A Better Entrepreneur

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    Just imagine a pill you can take to enhance your points of view, increase your memory, and make you more productive. In it sounds like an ultimate life hack, you’re not the only one.

    There are pills that guarantee that out there, yet how they work is a little complicated.

    These pills are known as nootropics or smart drugs.

    So what are nootropics?

    Nootropics are a class of brain power enhancing supplements that are utilized to enhance focus and help to boost memory. Nootropics are regularly used to increase capacity to focus, help people concentrate more and reduce anxiety.

    You will often observe Nootropics called as “smart drugs” as they are connected with increased intelligence, focus and motivation.

    Be they are not at all like brilliant medications which can frequently bring about negative reactions or side effects with long term use. Nootropics are safe to use and pose a low risk of any side effects if used properly.

    Numerous nootropics have similar systems of working by improving communication between neurons in your brain, adjusting neurotransmitter levels or by balancing brain cell health.

    They also improve metabolism of your neurons, support neuroplasticity, or even support the development of new neurons and neurotransmitters.

    How Nootropics work?

    There are various sorts of Nootropic supplements accessible. Also, there are distinctive classifications and “families” of Nootropics, for example, Racetams and Ampakines.

    Each of these particular supplements work in different ways and have different working mechanism. Given this, there is not one answer to the question “How Do Nootropics Work?” rather a wide range of answers.

    There are however some basic ways in which nootropics work and modulate the neutrons in your brain. One of them is listed below

    Together, the neurotransmitters and the receptors make up a “framework.” There are an immense huge number of these neuronal frameworks inside the mind.

    What a Nootropic supplement does, generally, is to explicitly target and increase the proficiency of those frameworks which result in enhanced cognitive abilities.

    How Nootropics will make you a better entrepreneur?

    The initial step for an entrepreneur is to investigate what they are doing battling against. For some (myself included) it is to enhance focus and effectiveness during the working hours was my primary objective.

    Diehard business people working 18-hour days require to last longer during the day and work normally when sleep deprived.

    This is where nootropic role come into play. Below are the benefits of nootropics that will help you to become a better entrepreneur.

    1. Increase concentration

    Before you consider enhancing your memory capacities, you should first increase your concentration. Nootropics can help with that, particularly in case you can’t concentrate on a particular work over a longer period of time. This is a noteworthy issue with entrepreneurs who encounter inconvenience in concentrating for longer hours of work.

    2. Enhances memory

    It is easy to read and comprehend a specific topic but the vast majority discover it somewhat troublesome to recover data from their memory. Nootropics have appeared to have beneficial outcome on a man’s memory.

    It enhances and repairs all parts of your memory capacities, including the working memory and recall. It additionally supports brain cell development and enhances the connections between the neurons. Aside from these advantages, they additionally repair the neuron, which thusly gives a help in comprehension of data information and recalling it.

    3. Improves brain health

    With busy schedule and poor diet, out brain takes a genuine bashing. Nootropics not only enhance your memory and information investigation but also improves the overall health of brain. They increases oxygen stream to the brain and maintains neurons and brain cells which keeps the brainwaves casual and more effective.

    4. Better mood

    The primary reason behind why many individuals can’t concentrate and focus at a specific task is foul mood. A few studies demonstrate that improper eating habits and sleeping habits can affect your mood. Nootropics can boost and stimulate mood enhancing neuroreceptors which makes your mood better and helps you to concentrate more.

    Conclusion

    Being an entrepreneur is not an easy job. You have to think outside the box that will make your business grow. Nootropics can help you to concentrate more and help you make your product awesome. If with a single nootropic you do not see significant results, you can combine different nootropics to see greater results. This is known as nootropic stacks.

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    Source by Ritika Singh

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  • Marketing Strategy: 7 Steps to Market Segmentation

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    Market segmentation is widely defined as being a complex process consisting in two main phases:

    – identification of broad, large markets

    – segmentation of these markets in order to select the most appropriate target markets and develop Marketing mixes accordingly.

    Everyone within the Marketing world knows and speaks of segmentation yet not many truly understand its underlying mechanics, thus failure is just around the corner. What causes this? It has been documented that most marketers fail the segmentation exam and start with a narrow mind and a bunch of misconceptions such as “all teenagers are rebels”, “all elderly women buy the same cosmetics brands” and so on. There are many dimensions to be considered, and uncovering them is certainly an exercise of creativity.

    The most widely employed model of market segmentation comprises 7 steps, each of them designed to encourage the marketer to come with a creative approach.

    STEP 1: Identify and name the broad market

    You have to have figured out by this moment what broad market your business aims at. If your company is already on a market, this can be a starting point; more options are available for a new business but resources would normally be a little limited.

    The biggest challenge is to find the right balance for your business: use your experience, knowledge and common sense to estimate if the market you have just identified earlier is not too narrow or too broad for you.

    STEP 2: Identify and make an inventory of potential customers’ needs

    This step pushes the creativity challenge even farther, since it can be compared to a brainstorming session.

    What you have to figure out is what needs the consumers from the broad market identified earlier might have. The more possible needs you can come up with, the better.

    Got yourself stuck in this stage of segmentation? Try to put yourself into the shoes of your potential customers: why would they buy your product, what could possibly trigger a buying decision? Answering these questions can help you list most needs of potential customers on a given product market.

    STEP 3: Formulate narrower markets

    McCarthy and Perreault suggest forming sub-markets around what you would call your “typical customer”, then aggregate similar people into this segment, on the condition to be able to satisfy their needs using the same Marketing mix.

    Start building a column with dimensions of the major need you try to cover: this will make it easier for you to decide if a given person should be included in the first segment or you should form a new segment. Also create a list of people-related features, demographics included, for each narrow market you form – a further step will ask you to name them.

    There is no exact formula on how to form narrow markets: use your best judgement and experience. Do not avoid asking opinions even from non-Marketing professionals, as different people can have different opinions and you can usually count on at least those items most people agree on.

    STEP 4: Identify the determining dimensions

    Carefully review the list resulted form the previous step. You should have by now a list of need dimensions for each market segment: try to identify those that carry a determining power.

    Reviewing the needs and attitudes of those you included within each market segment can help you figure out the determining dimensions.

    STEP 5: Name possible segment markets

    You have identified the determining dimensions of your market segments, now review them one by one and give them an appropriate name.

    A good way of naming these markets is to rely on the most important determining dimension.

    STEP 6: Evaluate the behavior of market segments

    Once you are done naming each market segment, allow time to consider what other aspects you know about them. It is important for a marketer to understand market behavior and what triggers it. You might notice that, while most segments have similar needs, they’re still different needs: understanding the difference and acting upon it is the key to achieve success using competitive offerings.

    STEP 7: Estimate the size of each market segment

    Each segment identified, named and studied during the previous stages should finally be given an estimate size, even if, for lack of data, it is only a rough estimate.

    Estimates of market segments will come in handy later, by offering a support for sales forecasts and help plan the Marketing mix: the more data we can gather at this moment, the easier further planning and strategy will be.

    These were the steps to segment a market, briefly presented. If performed correctly and thoroughly, you should now be able to have a glimpse of how to build Marketing mixes for each market segment.

    This 7 steps approach to market segmentation is very simple and practical and works for most marketers. However, if you are curious about other methods and want to experiment, you should take a look at computer-aided techniques, such as clustering and positioning.

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    Source by Otilia Otlacan

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