Tag: Strategy

Medical Product Alert N°2/2020
This Medical Product Alert relates to a confirmed falsified human immunodeficiency virus (HIV) in vitro diagnostic medical device (IVD) that has been identified circulating in Guyana and Kenya.

Through its Global Surveillance and Monitoring System (GSMS) for substandard/falsified medical products,
WHO was informed that at least 8,240 falsified rapid diagnostic tests to detect HIV-1/2 have been distributed in Guyana at end-user level. The product is Uni-Gold™ HIV and claims to be manufactured by
Trinity Biotech plc. Subsequent reports
revealed that the same falsified product is also circulating in Kenya.

Uni-Gold™ HIV is a single-use rapid diagnostic test – an immunoassay for the qualitative detection of antibodies to HIV-1 and HIV-2 in serum, plasma and whole blood. Uni-Gold™ HIV is intended for use in point of care settings as an aid
in diagnosis of HIV-1 and HIV-2 infection.

The WHO testing strategy recommends three HIV reactive test results to confirm an HIV-positive status in a
patient. The use of this falsified Uni-Gold™ HIV, subject of WHO medical product alert n°2 of 2020, is likely to lead to delayed diagnosis of HIV status.

Table 1: Specific details of the falsified product Uni-Gold™ HIV, subject of WHO Medical Product Alert n°2 of 2020

Product Name

Uni-Gold™ HIV

Lot Number

HIV7120026

Expiry Date

5 DEC 2020

Stated manufacturer

Trinity Biotech

The packaging of this falsified HIV test kit is in English.

The genuine manufacturer (Trinity Biotech plc) has confirmed that:
- They did not manufacture the falsified product in Table 1.
- Genuine lot HIV7120026 was made by Trinity Biotech plc and expired in 2019.
- The expiry date is incorrect and does not correspond with their batch manufacturing records.
Photographs and advice to the public are available below.

Figure 1 – Falsified Uni-Gold™ HIV, lot number HIV7120026, displaying falsified expiry date

Figure 2 – Falsified Uni-Gold™ HIV, displaying labelling inconsistencies

Advice on action to be taken by end-users:
- Please check to see if any Uni-Gold™ HIV test kits in your facility have lot number HIV7120026.
- If you are in possession of these falsified test kits with lot number HIV7120026:
1. Please do not use.
2. Please immediately contact the organization that supplied you with the product (either your HIV testing programme, nongovernmental organization or local distributor).
3. Please contact Trinity Biotech plc
Phone : +353 1 276 9800

E-mail : hiv@trinitybiotech.com
1. Please contact your national health authorities
All medical products must be obtained from authentic and reliable sources. Their authenticity and condition should be carefully checked.

Advice on action to be taken by national health authorities:

WHO requests increased scrutiny within the supply chains of all countries, particularly at testing sites (health facilities, community-based), clinical laboratories, medical stores/warehouses, and at the facilities of relevant economic operators (agents,
authorized representatives, distributors, wholesalers, etc.).

If these falsified test kits with lot number HIV7120026 are discovered, please do not use.

National health authorities are asked to immediately inform WHO, if these falsified products are discovered in their country using the WHO IVD complaint form.

If you have any information concerning the manufacture, distribution, or supply of this product, please contact rapidalert@who.int

WHO Global Surveillance and Monitoring System for Substandard and Falsified Medical Products

For further information, please visit our website: https://www.who.int/medicines/regulation/ssffc/en/

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https://www.who.int/news-room/detail/27-03-2020-medical-product-alert-n-2-2020

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April 1, 2020
Adding Text Messaging to Your Marketing Mix

With a consumer culture that has become increasingly reliant on mobile devices, choosing to add text messages to a marketing strategy can be a wise decision for companies looking to stay relevant and fresh. Text messaging marketing represents several unique benefits, allowing sales to be increased at a relatively low overall cost. Unlike traditional advertising methods, text messages are rarely ignored by consumers, further solidifying their role in a well-developed marketing plan. Before launching into the domain of text messaging, it is vital for marketers to keep a few essentials in mind. Utilize the following tips to make certain that text messaging integrates seamlessly into an existing marketing plan…

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http://www.associationofmarketing.org/articles/view.php?article_id=6783

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March 31, 2020
World TB Day 2020 Newsletter

Latest news and updates from WHO

Dear colleagues and friends,

World TB Day, this year, comes at a sobering time – as the world grapples with the COVID-19 pandemic. We stand in solidarity with those affected, those at the frontlines of the fight to combat COVID-19, as well as those who continue efforts to support
those ill with longstanding health problems like TB, HIV and other diseases. However, we cannot forget the millions and their families who battle TB every day and lose their lives to this ancient disease – which remains the world’s top
infectious killer.

As eloquently emphasized by WHO Director-General Dr Tedros Adhanom Ghebreyesus in his press briefing on COVID-19 yesterday, “I’d like to remind everyone that although COVID-19 is dominating the world’s attention-there is another respiratory
disease that is both preventable and treatable, but kills 1.5 million people every year – that disease is tuberculosis”

“It’s Time”, the focus for World TB Day this year is therefore on urgently accelerating the TB response to save lives and end suffering, even in times of crisis. This will be essential if we are to reach the targets and commitments made
by Heads of State at the 2018 UN High Level Meeting on TB.

We have made important strides against the TB epidemic to date.

We announced last year, that more people received life-saving treatment for tuberculosis in 2018 than ever before, largely due to improved detection and diagnosis. Globally, 7 million people were diagnosed and treated for TB – up from 6.4 million in 2017
– enabling the world to meet one of the milestones towards the United Nations political declaration targets on TB and the WHO Director-General Flagship Initiative Find.Treat.All End TB jointly with Stop TB Partnership and the Global Fund. This
has been a big win for the TB community.

WHO is working with countries to roll out important guidelines, including a comprehensive package on TB preventive treatment released today, and updated MDR TB guidelines to promote the use of all-oral regimens for patients with drug-resistant TB which
would be helpful – particularly at this point, when visiting health centers is a challenge. Furthermore, WHO has developed a note to guide and urge countries to ensure continuity of TB services during the COVID-19 pandemic.

We are strengthening our collaboration with civil society – more information is highlighted in the WHO Civil Society Taskforce Progress Review released today.

Youth mobilization is being ramped up through the WHO 1+1 Youth Initiative to end TB and the Global Youth Declaration to End TB. Multisectoral accountability is being promoted in countries through our framework and we have finalized a new global strategy
on TB research and innovation, that will be reviewed by the World Health Assembly.

Yet, the gains we have made are at risk – if there is any slackening of commitment and action, especially in times of crisis.

We are at a crossroads and we need to unite forces to take the path of success that will save lives and end suffering.

I was especially heartened today, to see the TB community coming together like never before. We all took our events to the virtual realm due to COVID-19 lockdowns. The WHO Online Talk Show held this afternoon, had a powerful line up of speakers that included,
TB survivors and advocates, civil society, high level government representatives, heads of agencies, researchers and partners. As of this evening we have surpassed 10,000 views on YouTube. I also participated in townhalls organized by Stop TB Partnership.
Our joint efforts have indeed ensured a continuing spotlight on those affected by TB, and clearly shows that no matter what the barrier, we can surpass it if we work together.

I am proud to stand shoulder-to-shoulder with you all virtually – and recommit to champion End TB efforts till we reach the finish line.

It’s time to deliver on our promises and ensure no one is left behind.

It’s time to End TB!

Dr Tereza Kasaeva
Director
Global TB Programme
World Health Organization

World TB Day Talk Show

In the backdrop of the global battle against COVID-19, WHO organized a special online talk show to mark World TB Day 2020. The talk show had a powerful line up of speakers from among TB survivors and advocates, civil society, high-level government representatives,
heads of agencies, researchers and partners. The video was streamed live on WHO’s Youtube channel crossing over 10,000 views in a few hours. Watch the talk show video

Spotlight on TB Preventive Treatment

New WHO recommendations to prevent tuberculosis aim to save millions of lives

24 March 2020 News release

Geneva – New World Health Organization (WHO) guidance will help countries accelerate efforts to stop people with tuberculosis (TB) infection becoming sick with TB by giving them preventive treatment. A quarter of the world‘s population
is estimated to be infected with TB bacteria. These people are neither sick nor contagious. However, they are at greater risk of developing TB disease, especially those with weakened immunity. Offering them TB preventive treatment will not only protect
them from becoming sick but also cut down on the risk of transmission in the community. Read more

The full package is available below and at our World TB Day Campaign Page

WHO Civil Society Taskforce on TB: Progress Review

The WHO Civil Society Taskforce provides a platform for meaningful engagement of civil society, building on the commitment of the Director-General, with emphasis on harnessing the untapped potential in engagement with civil society and affected communities
al all levels. To mark World TB Day 2020, the Task Force has released a Progress Review highlighting key achievements since its formation in 2018.

Access link here

WHO eTB guidelines: A digital platform to promote adolopment of TB recommendations

WHO Global TB Programme / McMaster University

The WHO Global Tuberculosis (TB) Programme, in collaboration with McMaster University, Canada, is developing a smart platform to improve access to and use of all WHO recommendations on TB prevention and care. The WHO eTB guidelines platform will facilitate
the adoption, adaptation and implementation (“adolopment”) by countries of recommendations across the continuum of care. This digital platform will provide a variety of users – TB programme managers, healthcare workers including
nurses, researchers, patients and affected communities – with easy access to all essential information about WHO-s current policy guidance on TB.

The first set of recommendations on TB preventive treatment were released on this new platform on World TB Day.

WHO eTB guidelines platform

Infographic

TB and COVID-19

24 March 2020 News release

Geneva – As the world comes together to tackle the COVID-19 pandemic, it is important to ensure that essential health services and operations are continued to protect the lives of people with TB and other diseases or health conditions. Health services,
including national programmes to combat TB, need to be actively engaged in ensuring an effective and rapid response to COVID-19 while ensuring that TB services are maintained. Read more

Let’s never forget: It’s time to end TB

Ksenia Schenina

Ksenia Schenina

24 March 2020 Photo story

On World TB Day 2020, the theme – “Its time” – stresses the urgency to end the TB epidemic. TB survivor and advocate, Ksenia Schenina, talks about her struggle with the disease, the persistence of stigma and the role that remembrance can play
in fighting it. Through her TB memorial project, she aims to remember those who passed away from this terrible and ancient disease. “We do it to show what kind of people they were – what kind of things they liked, what kind of music
they listened to and what their favorite movies were; if they liked fishing or dreamt of a flight to space,” she says. Read more

Commentary

To end TB, we must invest in research and innovation

24 March 2020 Commentary

If the world is to get anywhere near ending TB, a disease that killed more than 1.5 million people in 2018, something significant needs to change.

TB remains the world’s leading infectious killer and yet, in the last 50 years, only three new drugs and regimes have been developed to combat the disease. “What we need is more research and more tools in the pipeline; better diagnostics,
more effective vaccines, and safer, shorter drug regimes,” explains Dr Tereza Kasaeva, Director of the World Health Organization Global Tuberculosis Programme. Read more

Emily: A Day in the Life of a TB Nurse

Maria Emily C. Ballesteros

Watch this story of Emily, a nurse managing the tuberculosis (TB) program of the City Health Office in Tuguegarao City. Her dream for Tuguegarao is to one day see zero TB cases and that no one dies from this infectious disease. Nurses and healthcare workers
play a critical role in TB prevention and care. It’s time to invest in them to improve healthcare for all. We thank all the nurses, midwives and healthcare workers working to #EndTB! Watch the video

Updates and messages

New research tool supports scale-up of digital technologies to End TB

24 March 2020 TDR news item

National anti-tuberculosis efforts are increasingly involving digital technologies, such as mobile applications to support treatment adherence and electronic surveillance systems that enable real-time monitoring of a country’s TB situation. Read more

World TB Day 2020: It’s Time for solidarity

24 March 2020 HIV/TB news item

At this unique time in history when the world is grappling with the COVID-19 pandemic, the WHO Department of Global HIV, Hepatitis and STI Programmes stands in solidarity with governments and communities as they seek to maintain health services
and continue to address the needs of patients suffering from HIV and tuberculosis (TB). Read more

New, shorter treatment to prevent TB to be rolled out in five high TB burden countries

24 March 2020 news item

Three-month regimen expected to prevent TB in those at highest risk of developing the disease, including people living with HIV and children under the age of five
Today, the Aurum Institute and its partners, as part of the IMPAACT4TB project, announced that five high-burden TB countries will roll out a new, shorter drug regimen (known as 3HP) to prevent TB. The announcement comes as countries around the world mark World TB Day, which takes place every year on March 24th. Countries that will initially provide the new regimen with funding from Unitaid, U.S. PEPFAR and the Global Fund include Cambodia, Ethiopia, Kenya, Malawi, South Africa and Zimbabwe. More than 120,000 patient courses of 3HP will be delivered by the project to 12 countries in 2020. An additional 1 million patient courses are expected to reach low- and middle-income countries by the end of the year, through the combined support of Unitaid, Global Fund, the Stop TB Partnership’s Global Drug Facility (GDF) and PEPFAR. Read more

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https://www.who.int/news-room/detail/30-03-2020-world-tb-day-2020-newsletter

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March 31, 2020
5 Social Media Practices to Avoid

Online media rooms are the most important part of business promotion, and any online marketing strategy should involve social media marketing. This strategy is one of the most cost-effective ways to promote products, services, ideas, information, or the business itself. Regardless of its inexpensive nature, any mistake committed during social media marketing can cause businesses to lose more than they can afford. There are a few common social media mistakes that can be avoided to have a better chance of growth in the industry…

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http://www.associationofmarketing.org/articles/view.php?article_id=7483

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March 28, 2020
Schistosomiasis elimination: refocusing on snail control to sustain progress
Substantial progress has been made during the past decade to prevent and control schistosomiasis (also known as bilharziasis) globally. The disease affects more than 230 million people, mostly in sub-Saharan Africa.

Progress is mainly due to large-scale periodic treatment of affected populations with praziquantel, the only medicine recommended by the World Health Organization (WHO) against all forms of schistosomiasis. Regular treatment cures mild symptoms and prevents
progression to severe, chronic disease.

“Through progressive scale-up of periodic large-scale treatment
to control morbidity in many endemic countries, we are closer to
achieving the minimum target of 75% global coverage of all school‐aged
children,” said Dr Amadou Garba Djirmay, who leads WHO’s global schistosomiasis control programme. “But
if we want to achieve elimination, we must go a step further to
introduce snail control in hot spots and in areas targeting elimination.
This is bound to increase impact and accelerate progress towards
interruption of transmission.”

Expansion of treatment is largely supported by donated praziquantel from Merck KGaA of up to 250 million tablets annually. In 2018, almost 78 million children were treated, representing 63% of all school‐aged children eligible for treatment.

Transmission: role of snails

Schistosomiasis is an acute, chronic parasitic disease caused by infection with trematode worms of the genus Schistosoma. It is prevalent in tropical and subtropical areas, especially in poor, rural communities that have little or no access to
safe drinking‐water and basic sanitation. Infection is transmitted when people suffering from schistosomiasis contaminate freshwater sources when evacuating urine and faeces containing the parasite’s eggs.

Once an egg comes into contact with fresh water, it releases miracidia (hatchlings) which enter a snail and produce hundreds of cercariae (larvae) daily. The cercariae enter the human body on contact with the skin and develop into adult worms.

Besides treatment with praziquantel, eliminating snail hosts and improving sanitation are important methods for sustainable prevention of the disease. Dam and irrigation projects are known to be potential sites for outbreaks of the disease. Snail management,
often achieved through mollusciciding, can help to reduce transmission by eliminating these intermediate snail hosts.

Vector control

In 2017, the World Health Assembly – WHO’s decision making body – adopted resolution WHA70.16 on the Global Vector Control
Response, calling on Member States to develop or adapt national vector control strategies and operational plans. The strategy aims to reduce by at least 40% the incidence of vector borne diseases, including schistosomiasis, by 2025.

In response, WHO is reinforcing snail control as part of its strategic approach to achieve the target of eliminating schistosomiasis as a public health problem and, ultimately, the goal of elimination of transmission. Snail control will complement mass
treatment campaigns and sustain the public health impact of this core intervention.

To facilitate implementation of snail control, in 2019 WHO published on specific, standardized procedures and criteria for efficacy
testing and evaluation and in 2017 a manual on the use of molluscicides in the field. WHO is also planning to strengthen capacities
of health staff in medical malacology in order to reinforce snail control activities in countries.

In the past, molluscicides (particularly niclosamide¹ based products) were widely used in schistosomiasis control programmes. For example, in China programmes largely relied on snail control for over 30 years to overcome the disease as a public
health problem. In other parts of the world, however, snail control programmes were gradually discontinued and competencies faded away.

“Snail control is a crucial component of the global schistosomiasis elimination strategy,” said Dr Rajpal Yadav, Scientist, WHO Department of Control of Neglected Tropical Diseases. “It
is time we look for new snail control products that are cost–effective
and of low risk to humans and the environment. Some efforts are being
made to explore molluscicide compounds from plants, marine algae and
microorganisms.”

An integrated control strategy involving mass treatment with praziquantel, snail control and environmental modification, wider access to sanitation and safe water, economic and environmental development, health education and poverty-alleviation can greatly
contribute to sustainable control and elimination of schistosomiasis.

WHO’s new road map on neglected tropical diseases for 2021–2030, due to be launched later this year, advocates enhanced financial and political support to achieve the target of interruption of transmission. Additional research to address gaps,
develop tools and optimize the impact of existing programmes with snail control will complement the core strategic approach.

Schistosomiasis: forms of the disease

There are two major forms of schistosomiasis – intestinal and urogenital.

Intestinal schistosomiasis usually results in diarrhoea and blood in the stool; enlargement of the liver and of the spleen and portal hypertension are common in advanced cases.

Urogenital schistosomiasis is characterized by the presence of blood in the urine. Chronic infection results in fibrosis of the bladder and ureter that can evolve to hydronephrosis and create conditions for bladder cancer.

In women, urogenital schistosomiasis can cause vaginal bleeding, pain during sexual intercourse and nodules in the vulva, a condition now described as female genital schistosomiasis. In men, urogenital schistosomiasis can induce disease in the seminal
vesicles and prostate.

¹Limitations with the use of formulations based on niclosamide include restrictions on the usage of water immediately after application and temporary toxicity to non-target aquatic organisms including
fish, amphibians and invertebrates.
Read More
https://www.who.int/news-room/detail/25-03-2020-schistosomiasis-elimination-refocusing-on-snail-control-to-sustain-progress

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March 27, 2020
Using SlideShare to Generate Leads

Visual content marketing is motivating marketers to rethink their overall marketing strategy. Previously, written content was enough to make the marketing strategy of many business work effectively. However, it isn?t enough anymore. Now, it takes more than that to get the message to existing and prospective clients…

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http://www.associationofmarketing.org/articles/view.php?article_id=7875

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March 26, 2020
WHO urges countries to ensure the continuity of malaria services in the context of the COVID-19 pandemic

The COVID-19 pandemic is testing the resilience of robust health systems around the world. Recognizing the heavy toll that malaria exacts on vulnerable populations in sub-Saharan Africa, as well as the region’s fragile health infrastructure, WHO underlines the critical importance of sustaining efforts to prevent, detect and treat malaria.

“As COVID-19 continues its rapid spread, WHO would like to send a clear message to malaria-affected countries in Africa,” said Dr Pedro Alonso, Director of the WHO Global Malaria Programme. “Do not scale back your planned malaria prevention, diagnostic and treatment activities. If someone living in a place with malaria develops a fever, he or she should seek diagnosis and care as soon as possible.”

Ensuring access to core malaria prevention measures is an important strategy for reducing the strain on health systems; these include vector control measures, such as insecticide-treated nets and indoor residual spraying, as well as chemoprevention for pregnant women and young children (intermittent preventive treatment in pregnancy, intermittent preventive treatment in infants and seasonal malaria chemoprevention). Additional special measures could ease the burden on health systems in the context of COVID-19, such as presumptive malaria treatment and mass drug administration.

Any interventions must consider the importance of both lowering malaria-related mortality and ensuring the safety of communities and health workers. WHO will provide guidance for countries to safely maintain essential health services in the context of the COVID-19 response.

About COVID-19

COVID-19 is the infectious disease caused by the most recently discovered coronavirus. This new virus and disease were unknown before the outbreak began in Wuhan, China, in December 2019. Essential information on the COVID-19 pandemic can be found in a dedicated WHO site.

About malaria

Malaria is a preventable and treatable disease caused by parasites that are transmitted to people through the bites of infected female Anopheles mosquitoes. In 2018, there were an estimated 228 million cases of malaria worldwide and 405 000 malaria-related deaths. For more on malaria, visit: www.who.int/malaria

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https://www.who.int/news-room/detail/25-03-2020-who-urges-countries-to-ensure-the-continuity-of-malaria-services-in-the-context-of-the-covid-19-pandemic

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March 26, 2020
UK has enough intensive care units for coronavirus, expert predicts

Neil Ferguson, whose modelling has informed the UK’s coronavirus strategy, says that the need for intensive care beds will come close to, but not exceed, national capacity

Read More
https://www.newscientist.com/article/2238578-uk-has-enough-intensive-care-units-for-coronavirus-expert-predicts/?utm_campaign=RSS%7CNSNS&utm_source=NSNS&utm_medium=RSS&utm_content=home

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March 25, 2020
The Power of Social Media âe” Discover Your Strategy and Drive Results

When used strategically and cleverly, social media plays out to be the most powerful tool for market research and marketing. Investing in setting up an online version of your business with popular social media sites will be instrumental in getting new business and expanding your customer base and support group…

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http://www.associationofmarketing.org/articles/view.php?article_id=7962

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March 25, 2020
Webcast replay: Navigating your journey to retirement

In this replay of a recent webcast, Colleen Jaconetti, who is a senior investment strategist with Vanguard Investment Strategy Group, and Jessica McBride, who is a senior financial advisor with Vanguard Personal Advisor Services®, will discuss certain things you can do now to help ensure that your retirement will be as comfortable as possible.

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https://investornews.vanguard/webcast-replay-navigating-your-journey-to-retirement/

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March 21, 2020

*Product Name*	Uni-Gold™ HIV
Lot Number	HIV7120026
Expiry Date	5 DEC 2020
Stated manufacturer	Trinity Biotech

Tag: Strategy

Latest news and updates from WHO

World TB Day Talk Show

Spotlight on TB Preventive Treatment

WHO Civil Society Taskforce on TB: Progress Review

WHO eTB guidelines: A digital platform to promote adolopment of TB recommendations

TB and COVID-19

Let’s never forget: It’s time to end TB

Commentary

Emily: A Day in the Life of a TB Nurse

Updates and messages

Transmission: role of snails

Vector control

Schistosomiasis: forms of the disease