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Tag: Number

  • Researchers explore epigenetic influences of chronic pain

    Researchers explore epigenetic influences of chronic pain

    Chronic pain is one of the most prevalent, disabling and expensive public health crises in the United States. It affects more than 100 million Americans, with annual costs estimated at $635 billion, says a 2014 report from the American Pain Society.

    Despite the enormous societal impact of chronic pain, present treatment options are limited to nonsteroidal anti-inflammatory drugs (NSAIDS), opioids, anticonvulsants and antidepressants, which provide pain relief to only about half of patients. Furthering the problem, prescription opioid overdoses have quadrupled since 1999. There were more than 45,000 painkiller-related deaths in 2014 alone, according to the Centers for Disease Control and Prevention.

    Now, researchers at Drexel University College of Medicine are aiming to identify new molecular mechanisms involved in pain. Their latest study, published this month in Epigenetics & Chromatin, shows how one protein – acting as a master controller – can regulate the expression of a large number of genes that modulate pain.

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  • Heating and cooling that anticipates your needs

    Heating and cooling that anticipates your needs

    According to a recent survey, about half of Americans feel their office is either too hot or too cold. A number of factors play into this issue of thermal comfort, but the hardest factor to control for is the one we’re most interested in: humans themselves. Clothing choice and body shape are intrinsically tied to what temperature an individual will be most comfortable at.

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  • Businesses Pursuing New Product Development

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    With the aftermath of globalization, companies are carefully thinking about the best ways to extend their product and service offering. Thus, product development strategy is critical for their success. Yet, many companies are in defensive mode and merely want to maintain the position in the market place.

    However, staying in a holding position is a definite way for companies to be left behind. Innovative thinking that allows for product/service growth is a too sure way for sustainable success. In today’s discussion, we will explore the importance of product development for the growth of businesses, especially in a competitive market.

    Launching into new product offerings is not easy. According to one market research, approximately 75% of consumer-packaged goods and retail products fail to earn even $7.5 million during their first year. Harvard Business School Professor, Clayton Christensen, who is the world’s foremost authority on disruptive innovation, suggests that the failure rate of new products may actually be as high as 95%. Product failure rates relate to the number of products that are launched commercially but fail.

    Geoffrey A. Moore, the author of Crossing the Chasm, maintains the challenges of product deployment: “… the less successful product is often arguably superior. No content to slink off the stage without some revenge, this sullen and resentful crew casts about among themselves to find a scapegoat, and whom do they light upon? With unfailing consistency and unerring accuracy, all fingers point to-the vice president of marketing. It is marketing’s fault!” Thus, new product development is a risky proposition to senior executives making these critical positions as well as the organization as a whole.

    Businesses that want sustainable growth must develop new product and services often and consistently. Philip Kotler and Kevin Keller, authors of Marketing Management, “In an economy of rapid change, continuous innovation is a necessity. Highly innovative firms are able to identify and quickly seize new market opportunities.”

    In taking any actions on new product development, businesses should think strategically about their product development. Alexander Chernev, the author of Strategic Marketing Management, further argues that managing growth is the most preferred route to profitability compared to just cutting cost.

    He outlines four key issues in managing growth, which include: (a) gaining and defending a market position, (b) managing sales growth, (c) new product development, and (d) product-line management. Chernev maintains, “New products and services are the keys to sustainable growth; they enable companies to gain and sustain their market position by taking advantage of the changes in the market to create superior customer value.”

    With that said, new product development meaning having the ability to take a product or service idea and convert it into a tangible offering that customers want. The following are the steps that more products undergo for market consumption: (a) idea generation, (b) concept development, (c) business analysis, (d) product development, (e) market testing, and (f) business deployment.

    The Ansoff Matrix is a strategic tool for product development, consisting of market penetration, market development, product development, and diversification. In market penetration strategy, organizations seek to grow using its existing product offerings in existing markets. With this strategy in mind, organizations try to increase market share. In a market development strategy, companies try to expand into new markets like new buyers using their existing offerings. In product development strategy, businesses seek to create new products and services targeted at its existing buyers.

    In a diversification strategy, an organization tries to grow its market share by introducing new product offerings while at the same time entering a new market. Diversification is the most-risky approach due to simultaneous making new changes (new product, new market). Kotler and Keller further maintain the difficulty of sustainable product success: “It is increasingly difficult to identify blockbuster products that will transform a market, but continuous innovation can force competitors to play catch-up.” The concept sounds easy. However, it is riddled with problems.

    Without a doubt, many companies know that product development is a risky business. Although many consumers will proudly proclaim the success of many innovative products like Apple and Google, these same buyers are not aware of the numerous product launch failures in this country. In our discussion, I demonstrated the importance of product development for the growth of businesses, especially in a competitive market. Failures often lead to innovation.

    American great inventor, Thomas Edison, had his own share of failures, but learned how to innovate because of them: “I have not failed. I’ve just found 10,000 ways that won’t work.” Likewise, today’s businesses can also achieve success if they understand how to deploy their products and services to the marketplace strategically. Although there is enormous danger in failure, there is also the opportunity of unforeseen growth. Don’t wait until it’s too late.

    © 2017 by DD Green

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    Source by Dr. Daryl D. Green

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  • Ten Ways to Offer Better Customer Service

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    Today’s savvy customers not only want excellent service, they often expect it. Customer service was the main quality focus of growth and improvement for companies in the last few decades, which is why many now expect it. Companies can lose customers over bad customer service and may retain customers who feel treated respectfully. How well customer service works depends greatly on the attitude and training of company human resources, even those not in the service areas. Below are a few ways everyone can improve their customer service skills and attitudes. 

    1. Always smile when speaking with the customer, whether in person or on the phone. Smiling lifts your attitude and the positive ness can be heard in your voice. 
    2. Greet customers by saying hello, giving them your name, and asking them how you can help.
    3. Whenever possible, be empathetic. Let the customer know you understand their feelings and want to be of help in solving their problem.
    4. Be sure to ask for their name so you can call them by it when responding. This makes the conversation seem more one-on-one friendly rather than combative. If you are on the phone, get their phone number too in case you become disconnected or need to do research. With their phone number, you can call them back if necessary.
    5. If you must put a phone customer on hold or your computers are down, let them know how long the hold or downtime might be. If it will be more than a couple of minutes, you should give them the option of holding or having you calling them back when you have completed your research or when the computers come back up. The customer may choose to call you back, but never tell them that is what they must do. Be sure to call them back in the stated timeframe even if it is only to say you still do not have an answer. Lack of communication is often more frustrating for a customer than having to wait a little longer for results.
    6. If the customer is angry or determined to complain, stay calm and don’t take their criticism personally. Ask questions so you can get to the root of the problem or issue. However, do consider their criticism as suggestions for future improvement of your company processes and services.
    7. If you do not have an answer for the customer, do not make something up. Instead find someone who can give you the correct answer. Customers don’t like being lied to or patronized.
    8. Find the best way to resolve the problem and satisfy your customer without having to go through multiple levels of approval or breaking any rules. Multiple levels of approval only slow the process down and do not help the customer, so avoid them whenever possible. However, if you must get an approval, let the customer know the process and how long it may take and exactly when they can expect a result. You can often go the extra mile for the customer without breaking any rules or going against written policies. 
    9. Once the customer’s problem is resolved, ask if you can be of any help with anything else. Be sure to thank the customer before saying goodbye. 
    10. Always remember the golden rule is the best rule of thumb for customer service “Do unto others as you would have them do unto you.” 

    These are simple ideas to improve customer service skills and attitudes in employees. It is important to always remember that customers today expect excellent customer service and will go where they can find it. Companies lose customers over bad service. So offer great service instead to help retain customers.

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    Source by Shirley Lee

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  • Three Reasons Why Money Was The Worst Invention Of All Time

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    Who invented money? Ask any number of people and they couldn’t tell you who it was that actually invented money or where the idea came from. History has given us some bad ideas, but money has to be the worst and here are my top three reasons why.

    1. Something Invented By Man Should Not Have Power Over Him.

      If I think really hard and try to imagine a time without money, before it was invented and used on a daily basis, I tend to imagine that the world was a completely different place. People most likely had a barter type society where goods and services were exchanged and that is how one survived. If I had a particular skill, say hunting, and you were hungry you could come to me for food. The idea would be that if you could make fire, and I could provide the food, then we could exchange our skills or abilities and everyone got what was good for them. I assume, for the sake of argument, that if someone possessed absolutely no skills whatsoever, that person was still allowed to eat. I can’t imagine that I would loan the helpless soul some meat, only if it could be paid back somehow. Before helpless soul could blink, he might owe me for five dinners and then I have to send out the collection agents to call in his debts. Money provides control, in both a positive and negative control. Although it is man made, and essentially just a piece of paper or a mixture of cheap metals, money has power, and is power. I can just imagine Mr. Helpless Soul explaining to his wife that he can’t repay the hunter and doesn’t know what to do. So Mr. Hunter decides to enslave the Helpless Soul family until the debt is repaid. It is unfathomable to me that so many people in my country, and the world go hungry every day. Those who possess the money have the power to deny the needs of those that don’t have means. Where have the humanitarians gone? I’ve seen a business owner kick out a person who was homeless and starving, and then half an hour later deal with a complaining customer as he shouted that his food was not hot enough. Money only has the power that we give it. If we choose to see it as just a means to an end, or just some silly paper we have been told to obey our whole lives, then one can focus on what really matters. I am not advocating not paying debts, or shucking responsibilities. This is the world we live in, and norms must be followed…until the laws change again to suit what the politicians want on any particular whim of a day.

    2. Money Shifts Focus From Helping One Another To Arbitrary “Worth” Of Mere Things.

      Why should I do anything to help anyone else, unless they can pay for it? If my entire focus in life is to obtain material things, then I should only be motivated by money, or obtaining it, to do anything. What is anything really worth? Marketing companies have defined worth for me since I was a child, and it was beaten into me during commercial breaks of GI Joe. What is the value of all of the things you want in comparison to something that really matters? Imagine what the worth is of spending one more hour with a loved one before they pass away and are gone forever. The worth of teaching your children that there is more to life than money and obtaining things. The worth of feeding a homeless man, and helping him have at least one night’s sleep where his stomach doesn’t keep him awake. The value of reaching out a hand and helping someone else in this world is worth more than the largest diamond, the heaviest gold, and the purest oil. Now, I am the biggest hypocrite on this topic, because I love things! It has been programmed in me for so long, it is hard to shake the desire to obtain things. Imagine a life in which people helped each other because it is the right thing to do, and not just for what they could get in return. The argument is, well, that things can’t just be free. You have to pay something to get something. How would the world work if everyone was just giving away everything for free and everyone just had everything they needed and didn’t have to be slave to credit card companies anymore or to a job that they dislike? How would we survive? My answer to those questions is, famously! I would be free to learn a trade that benefits others and could use that ability to provide for my family and to help others. I have wanted to help by donating or giving my entire life, but never had the means. I’ve donated a little time here and there, and not near as much as I should or would have liked to, but at least it was something. But because I like things, and those things have cost me money, I have to continue in my job, and repeat the same cycle my father did.

    3. Money Makes You Question If People Really Care About You, Or Just Your Money.

      I try to envision the end of my life surrounded by those that have made my journey with me, who love and care for me because of the enrichment I gave to them through my friendship and dedication. In my latter years, enjoying my days with my wife, and talking to my grown children and my grand children. I want to soak up every single minute of my life between here and there. I want to feel and love and enjoy all that there is to offer. I have seen families destroyed, fighting over the money left behind after a loved one passes. Some of those grudges are held for the rest of their lives. They lose a relationship and also a loved one, and the only thing they can think about, is how much money they will be getting. More than likely, Mr. Entitlement as we will call him, won’t even miss the loved one that was lost. How many brilliant individuals never get the chance to succeed because of lack of means, and how many elite are given free passes because their pile of paper is bigger than yours. Do the people closest to you care about you or your money? Does the girlfriend only love you because of what you can buy her? Do your children only listen to you in order to get something they want? Take the money away, and would they abandon you? Such a great idea, this money.

    My answer to all of this is that I don’t have an answer. My two year old daughter asked me about money and loves putting money in her piggy bank. It made me start to consider all the reasons I worry about money, and fight about money, and read books about money. Nothing like the honesty of a child, to make you sit and think.

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    Source by Mitchell Pierce

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  • Combine Language Learning and Technology to Explode Your Teaching and Learning Success

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    Are you looking to boost your English language teaching or learning skills to yet ever higher levels? Would you like to stimulate more interest in your language classes or break out of a slump or plateau? Combine the use of a variety of language learning techniques with continually developing technology to spur your successes. Here are some useful ideas and web sites to get you started.

    BLOGS

    A Web Log or Blog, is not unlike a dairy you keep online. You can write instructions, an essay or post any type of information you want. Graphics and images can be included to illustrate the written material. Sound and audio-visual files can also be placed into a blog for added impact. A teacher can post a reading or assignment where students can comment right online. No papers, no clutter and you can view it almost any time. Blogs are becoming easier to use and access and many sites allow you to set one up for free.

    ONLINE VIDEO / AUDIO

    Most professionals have an e-mail address or two. Your e-mail can now become a communicative tool between you and the learners. E-mail can now also include the use of images and sound or audio-visual clips, as well as the message text. Learners can send in assignments as attachments or pasted into the body of the e-mail. They can ask questions and receive timely feedback without waiting for the next class session. Teachers can send out instructions, updates or other information to learners individually, or as a group also without having to wait for the next scheduled class session.

    No computer? No problem. In many parts of the world e-cafes are so cheap they’re actually a viable alternative that students can easily afford. Whole “communities” of young learners are based on hangouts at e-cafes in some cultures. Talk to your students about it. You might be surprised.

    USE OF ONLINE RESOURCES for TEACHING / LEARNING

    The use of online games, EFL practice sites student and teacher forums, communities and activities has exploded in recent months in many parts of the world. Virtual communities and online reference libraries now enable learners to problem-solve, research a paper or to more quickly complete assignments that formerly would have taken disproportionately large amounts of time to complete. For example, a few sites worth mentioning include:

    o http://www.books.google.com/

    A web site which offers free access to books that can be read on-screen

    o http://www.universia.net.co

    This is a site which has a lengthy listing of virtual libraries in almost any genre and connects more than 900 mostly Spanish language libraries

    o http://www.redclara.net

    This site interconnects an advanced academic network of Latin American libraries

    o http://www.lablaa.org

    This site allows you access and read a large number of its collected works online and contains exposition pages

    o The official Project Gutenburg web site contains an extensive listing of literary works in English which have entered the Public Domain. It’s online at: [http://promo.net/pg/]

    Try some of these useful ideas and web sites to get you started in combining the use of a variety of language learning techniques with continually developing technology to explode your English language teaching and learning successes. If you need to know more about using these or other new technologies to boost student interest and motivation making your English language teaching more effective, feel free to e-mail me at the address below with questions or comments.

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    Source by Larry M. Lynch

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  • Can Foam And Latex Pillows Be Dangerous To Your Health?

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    Memory foam pillows and latex pillows are the latest craze in pillow town. You couldn’t blame people who rush out to buy a set for themselves and the whole family. They’re extremely comfortable and without doubt provide excellent support that traditional pillows lack of. Other than they are a dream to sleep on, they are very economical as they last for years. Opposed to most pillows in the market, they don’t go flat over time. And you are guaranteed of pillows that are good as new every day for the years to come. That’s because of the technology applied in these pillows. The materials have the characteristic of being able to return to their normal shape and smooth out themselves from indentations left by your head. It’s as if they were never slept on!

    However, there are a lot of speculations about the danger these pillows pose to human health. Although they are labeled to be hypoallergenic, a number of people have been claiming to have gotten sick since they have acquired of these pillows.

    Latex pillows are made of rubber foam produced by sap from rubber trees. They are resistant to dust mites and mildew by nature. However, synthetic latex can outgas chemicals that may affect the human health. These pillows are of materials formulated from petroleum products.

    Because of the strong smell it emits, there were some users who complained of dizziness, nausea, headache, migraine and difficulty breathing. The smell however was reported to have subsided after a month or so. There weren’t much complaint filed as monitored by FDA.

    There are pillows out in the market that are made of natural latex and claim to be so 100%. They are processed naturally, washed off of proteins that might attract dust mites and free of chemicals. However, the glue used for layering could provoke allergies among sensitive users. It is safe to warn individuals allergic to latex to avoid using latex pillows.

    Memory foam pillows are made of NASA invented polyurethane from petroleum products. This synthetic material generates toxic waste by-products. The fact that it isn’t biodegradable should ring alarms. These pillows outgas volatile organic compounds that are toxic to human health. Although the smell dissipates, the toxic chemicals may penetrate your immune system. That is why hypersensitive people easily get sick from breathing organophosphate chemicals that are not easily detectable. Aside from reported dizziness, migraine, headache and asthma attack, there were also incidence of heart attack and other autoimmune disorders.

    Despite a few negative feedbacks, there are a number of people who are very happy with their latex and memory pillows. A lot has found their perfect match with them and has claimed to have provided the perfect solution for their sleep disorders.

    Although there were no clinical studies published nor publicized complaints, it is always better to be safe than sorry. There’s no harm in trying. Purchase these pillows with warranty or with money back guarantee so you would be able to judge for yourself.

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    Source by Greg J Dawson

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  • Numerology’s Secret Strength – Your Habit Challenge

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    Where do you turn in times of crisis? How do you find the inner strength to face problems which are beyond your normal strength? Numerology can tell you where your hidden strength lies, ready to come forth in the face of problems beyond your normal resources. This hidden strength is known as your Habit Challenge. This ability is also known as the Submerged Characteristic or Habit number. Normally it lays dormant, hidden in everyday life until you truly need it; Then it blossoms becoming a useful tool to be called on.

    Finding your Habit Challenge

    This is one of the simplest calculations in Numerology. You simple count the number of letters in your use name and then reduce the value with fadic addition. Your use name is what your friends call you, or how you introduce yourself. Note that since this can change through out your lifetime, your Habit Challenge will change as well. As an example, actress Angelina Jolie has a Habit Challenge value of (4) as shown below.

    Angelina Jolie (Habit Challenge) = (8 + 5) = (13) = (4)

    Habit Challenge (1) – Originality

    People with this value respond to crisis by turning to their originality. They are best served by looking to themselves to find the answers they need, usually to the complete surprise of those around them.

    Habit Challenge (2) – Collaborator

    People with this value respond to crisis by teaming up with others. They are best served by being a good follower and trusting their partners to direct them in reaching their goal. If a need for diplomacy occurs, they are truly in their element and will bring good results.

    Habit Challenge (3) – Creativity

    People with this value respond to crisis by turning to their imagination. If there is an artistic solution to their problems, then they will solve them. These souls will also find an ability to put aside their fears and not take their problems seriously, letting them work with little pressure.

    Habit Challenge (4) – Analysis

    People with this value respond to crisis by turning to pure logic and their analytical skills. They will be able to turn off their emotions and work towards a practical and orthodox solution to their problems. They will never break down or lose their head until the crisis has passed.

    Habit Challenge (5) – Flexible

    People with this value respond to crisis by being flexible. They will accept change and take risk as necessary to reach their goals. If there is a New or unusual solution to the crisis, they will find it. These people will exhibit great versatility and quick thinking throughout the crisis.

    Habit Challenge (6) – Responsible

    People with this value respond to crisis by showing sympathy for others and taking on responsibility for the problem they face. These souls will work to shield their friends and family from the affects of the crisis and offer to sacrifice themselves to resolve the problem.

    Habit Challenge (7) – Meditation

    People with this value respond to crisis by using meditation or other techniques to seek knowledge from within themselves to resolve their problems. These souls will reject advice which they have not asked for, and instead look to their intuition for ways to solve their problems. They will always act with perfect timing while the crisis last.

    Habit Challenge (8) – Ruthless

    People with this value respond to crisis by being ruthless and efficient in their actions toward solving their problems. These souls are willing to set ambitious goals and work tirelessly until they are met. They will exhibit determination and infinite patience until the crisis has passed.

    Habit Challenge (9) – Idealist

    People with this value respond to crisis by being an idealist. They will be broad minded in their dealings with others, and generous with their time and resources while the crisis last. These souls will react dramatically with great flare towards those who oppose them until their problems are resolved.

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    Source by Keith Abbott

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  • Student Loan Debt Clock Is Ticking Away At 1.57 Trillion Dollars On Election Day 2016

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    The academic bubble is ready to burst, all the while academics in their infinite wisdom tell us they know best how to run our society and civilization – don’t you find that odd? It seems they haven’t gotten their own house in order, and yet, want our entire country to run like a giant college campus – interesting indeed. These same academics want to tell us how to vote, re-distribute wealth, and how to think – well, I think their day of reckoning is right around the corner – and I fear what’s to come will not be pretty. No, I don’t want to be the one to say; “I told you so.” Surely, there are others with more social media followers who see the reality of the situation to spread that in-your-face slap when the time comes. Okay so, let’s talk shall we?

    40% of the student loans are in technical default (90-days in the rears with no further agreement to catch up on payments). That is 583 Billion Dollars in defaulted loans that we may never see payment of. Trust me when I tell you that the College Loan Bubble has burst and is extreme crisis. Why is this allowed to continue? Well, if it stops it will collapse academia, become a huge problem for our Federal Government, add over 1/2 Trillion to our $20 Trillion National Debt, and cause the angst of millennials who the Democrats have all but promised “Free College For All” during the 2016 Presidential Election.

    Still, by the time the election is over the Student Loan debt will be 1.57 Trillion Dollars, even though the official figures claim it only 1.2 Trillion which was actually the figure before the start of the 2015 Academic Year.

    If you don’t see the enormity of the problem, let’s talk about the auto industry right now. It turns out that the number of “Subprime” auto loan defaults are at another all-time high of 4.5% – Subprime meaning loans made to those without proof of ability to pay or marginal credit ratings, perhaps coming from low-socioeconomic borrowers. Last time this happened the auto industry crashed and needed a big bailout, and we are reaching those same numbers now – and realize this is only 4.5% not 40-50% like the student loan problem.

    Scared Yet? Well, it is Halloween 2016 today, and I am, and no, there won’t be any good witches flying in on their brooms to win the next election to use hocus pocus to make this problem go away – indeed, both presidential candidates are likely to see the auto loan problem get worse, as well as the student loan debt problem – not to mention our stock market breaking all-time highs with PE Ratios and major stock market indices records.

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    Source by Lance Winslow

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