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New WHO recommendations to prevent tuberculosis aim to save millions of lives
Geneva – New World Health Organization (WHO) guidance will help countries accelerate efforts to stop people with tuberculosis (TB) infection becoming sick with TB by giving them preventive treatment.

A quarter of the world‘s population is estimated to be infected with TB bacteria. These people are neither sick nor contagious. However, they are at greater risk of developing TB disease, especially those with weakened immunity. Offering them TB
preventive treatment will not only protect them from becoming sick but also cut down on the risk of transmission in the community.

As we mark World TB Day 2020, the disease remains the world’s top infectious killer. In 2018, 10 million people fell ill with TB worldwide and 1.5 million people lost their lives to this disease.

“COVID-19 is highlighting just how vulnerable people with lung diseases and weakened immune systems can be,“ said Dr Tedros Adhanom Ghebreyesus, WHO Director-General. “The world committed to end TB by 2030; improving prevention is key
to making this happen. Millions of people need to be able to take TB preventive treatment to stop the onset of disease, avert suffering and save lives”.

Dr Tedros highlighted the importance to continue efforts to tackle longstanding health problems, including TB during global outbreaks such as COVID-19. At the same time, programmes already in place to combat TB and other major infectious diseases
can be leveraged to make the response to COVID-19 more effective and rapid.

Although some progress has been made towards targets set at the UN high-level Meeting on TB in 2018, TB preventive treatment has been largely neglected. Global leaders committed to ensuring access to TB preventive treatment to at least 24 million contacts
of people with active TB and 6 million people living with HIV by 2022. To date only a fraction of that target has been reached, with countries putting less than 430,000 contacts and 1.8 million people on TB preventive treatment in 2018.

TB remains the top cause of death among people with HIV. TB preventive treatment works synergistically with antiretroviral therapy to prevent TB and save lives. Reinvigorated efforts by governments, health services, partners, donors and civil society
will be needed to increase access to TB preventive treatment to the levels targeted.

The new consolidated guidelines recommend a range of innovative approaches to scale up access to TB preventive treatment:
- WHO recommends a scale-up of TB preventive treatment among populations at highest risk including household contacts of TB patients, people living with HIV and other people at risk with lowered” immunity or living in crowded settings.
- WHO recommends an integration of TB preventive treatment services into ongoing case finding efforts for active TB. All household contacts of TB patients and people living with HIV are recommended to be screened
  for active TB. If active TB is ruled out, they should be initiated on TB preventive treatment.
- WHO recommends that either a tuberculin skin test or interferon-gamma release assay (IGRA) be used to test for TB infection. Both tests are helpful to find people more likely to benefit from TB preventive treatment
  but should not become a barrier to scale-up access. Testing for TB infection is not required before starting TB preventive treatment in people living with HIV, and children under 5 years who are contacts of people with active TB.
- WHO recommends new shorter options for preventive treatment in addition to the widely used 6 months of daily isoniazid. The shorter options that are now recommended range from a 1 month daily regimen of rifapentine plus isoniazid
  to 3 months weekly rifapentine plus isoniazid, 3 months daily rifampicin plus isoniazid, or 4 months of daily rifampicin alone.
“As people around the globe come together to commemorate World TB Day, WHO is calling on governments, affected communities, civil society organizations, health-care providers, donors, partners and the industry to unite forces and step up
the TB response – notably for TB preventive treatment – to ensure no one is left behind,” said Dr Tereza Kasaeva, Director of WHO’s Global TB Programme. “The new WHO guidance shows the way forward for millions to rapidly
access new tools and shorter, safer options for preventive treatment. The time for action is now.”

TB preventive treatment is an affordable intervention that can prevent families from sliding into poverty and preserve the health and economy of whole communities. WHO anticipates that as new and safer drugs come onto the markets, and as prices
fall, it will become a highly-cost effective way to save millions of lives.

NOTES FOR EDITORS:

WORK BY WHO AND PARTNERS

WHO works closely with Member States including the US Government and technical and funding partners such as UNITAID to enhance access to shorter TB preventive treatment regimens. UNITAID-supported projects such as IMPAACT4TB and Cap-TB projects
enabled by WHO with partners in Brazil, Cambodia, Cameroon, Côte d’Ivoire, Democratic Republic of Congo, Ethiopia, Ghana, India, Indonesia, Kenya, Lesotho, Malawi, Mozambique, South Africa, Uganda, United Republic of Tanzania and
Zimbabwe are leading the way. The new treatment options are also now more affordable, thanks to the significant price drop of rifapentine – a key drug – facilitated recently by UNITAID, the Global Fund to Fight AIDS, Tuberculosis and Malaria
and global biopharmaceutical company Sanofi, along with forthcoming arrangements underway with generic manufacturers.

MORE ABOUT THE GUIDELINES

The new consolidated WHO guidelines come with an operational handbook to help guide countries step-by-step as they take TB preventive treatment to scale. This includes guidance on how to prioritize and invest from demand creation for TB prevention
to supervision and monitoring of the programme.

The guidelines and operational handbook are also accompanied by an innovative mobile application – Prevent TB –to help health-care workers manage TB preventive treatment in their communities. Its online dashboard allows programme
managers to visualize and monitor data in real time. The application can be customized by countries to suit their specific settings and is currently being adopted in India and Philippines.

WORLD TB DAY

The new guidelines and tools are being released ahead of World TB Day. World TB Day is observed on March 24 each year to raise public awareness and understanding about the world’s deadliest infectious killer – TB and its devastating
health, social and economic impact on people around the world. Under the theme “It’s Time”, the spotlight this year is on urgently accelerating the TB response to save lives and end suffering.

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https://www.who.int/news-room/detail/24-03-2020-new-who-recommendations-to-prevent-tuberculosis-aim-to-save-millions-of-lives

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March 24, 2020
Covid-19 worldwide death toll nears 115,000

ANKARA: With the global death toll on Saturday approaching 115,000, health officials worldwide announced new cases in coronavirus’ continuing spread, Anadolu Agency reported.

The country with the highest loss of life due to coronavirus is Italy, where 4,032 people have so far died, after eclipsing China earlier this week.

Mainland China, where the outbreak started last December, was second, with a total of 3,255 people dead.

Iran had the third-highest death toll, with 1,433.

Australia reported that the number of cases of Covid-19 rose to 1,051, with 300 people added to the total in the last 24 hours.

Singapore’s Health Minister Gan Kim Yong said the number of cases in the country rose to 385, and it also claimed the lives of a 75-year-old Singapore woman and a 64-year-old Indonesian.

Morocco’s Health Ministry said the number of cases had risen to 86, including seven people who had recently been abroad.

Morocco on Friday declared a state of emergency over the outbreak.

Meanwhile, Paraguay’s Health Ministry announced on Twitter that a 69-nine-year old man had died from the virus after treatment in an intensive care unit.

Local media reported that the total cases number of cases in the country was 18.

President Mario Abdo Benitez announced that a quarantine declared for March 10 to April 4 has been extended to April 12. — Bernama

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https://www.thesundaily.my/local/covid-19-worldwide-death-toll-nears-115000-GA2165778

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March 21, 2020
(Video) Time for tough action against those flouting MCO

PETALING JAYA: Faced with the deadly Covid-19 virus, the government implemented the movement control order (MCO) as a lesser measure to contain the pandemic.

The MCO was favoured to a full lockdown as the latter might cause deep inconvenience to the people.

While the move, as a preliminary measure to counter the spread of the disease, was welcomed by the majority, it is not the case with a segment of obstinate Malaysians who are not adhering to the MCO and are going about their daily lives as usual, totally unperturbed by the pandemic.

Members of the police force are at their wits end.

Since the MCO came into force on Wednesday, it has been a gruelling task for personnel nationwide who are “chasing” those who continue to treat the order lightly. These selfish and stubborn individuals are taking to the outdoors without any concern for their own safety, that of their families and others who come in contact with them.

Should they become infected with the feared virus from their careless behaviour, these irresponsible individuals are a threat to the health of other Malaysians including those who abide by the MCO.

Law-abiding Malaysians viewed with utter disgust several videos which went viral since yesterday, showing a number of people who are turning the MCO into an outdoor leisure-seeking break.

One video taken in Johor Baru showed more than 50 adults and children passing their time at a playground in a residential area, playing basketball or idling away.

A police car arrives at the scene with its sirens blaring and beacons switched on but the crowd does not budge.

When a personnel makes an announcement with a hailer urging the people to return indoors in accordance with the MCO, it falls on deaf ears.

It was not until an exasperated policeman steps out of the patrol car and walks towards the people does the crowd decide to disperse.

Another video showed a group of men who were playing checkers in the open at an unnamed location in Selangor being advised to head indoors by police.

In Alor Star, police cars arrived at a house to advise its dwellers to call off a large kenduri they were holding.

Dozens of other videos of people enjoying meals, gathering, loitering and setting up food stalls, all outdoors, are making the rounds.

With the reckless behaviour of such Malaysians, perhaps it is time they face the full brunt of the law.

Laws of the Penal Code and Prevention and Control of Infectious Diseases Act 1988 should be invoked and police be given consent by the higher-ups to arrest and prosecute those who fail to adhere to the MCO.

This will not simply serve as a lesson to those who flout the law but also a deterrent to the rest.

This should be done at the soonest to further counter the pandemic and in honour of the sacrifices our frontliners who put their lives on the line – the hundreds of medical personnel caring for over 900 infected patients battling the disease and the thousands of police personnel upholding the MCO.

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https://www.thesundaily.my/local/video-time-for-tough-action-against-those-flouting-mco-MD2151817

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March 19, 2020
WHO teams with partners to mitigate the potential impact of the COVID-19 pandemic in malaria-affected areas
The rapid spread of COVID-19 is testing the resilience of robust health systems around the world. WHO and its partners are taking measures to mitigate the potential impact of sustained transmission of the coronavirus in malaria-endemic settings –
particularly in sub-Saharan Africa, which shoulders more than 90% of the global malaria burden.

To date, a small proportion of the global COVID-19 cases have been identified in malaria-affected countries. However, as of 17 March, 25 countries in the African Region had reported cases of COVID-19, and local transmission of the disease had been detected
in 6 countries (Algeria, Cameroon, Kenya, Rwanda, Senegal, South Africa).

“At this point, we still don’t know what the COVID-19 pandemic will look like in sub-Saharan Africa,” said Dr Pedro Alonso, Director of the WHO Global Malaria Programme. “But we do know that when public health emergencies have
hit parts of Africa with weak health systems and high malaria transmission, the impact on malaria disease and death has been very severe.”

The 2014-2016 Ebola outbreak in Guinea, Liberia and Sierra Leone, for example, undermined malaria control efforts and led to a massive increase in malaria-related illness and death in the 3 countries.

Joint action

To support malaria-affected countries, WHO has identified the need for a set of inter-related actions among global partners:
- generating, using and disseminating accurate information;
- mitigating against health system disruptions; and
- ensuring the continuity of routine malaria-specific interventions while also providing, where needed, additional emergency measures, such as mass drug administration, in health systems significantly impacted by COVID-19.
The Organization convened partners on 17 March to discuss areas of collaboration, coordination and next steps.

WHO has begun monitoring the evolving geographic location of COVID-19 cases to understand the extent to which the coronavirus and malaria affect the same target groups. This information will reveal who is likely to be at greatest risk, where and when,
and thus inform the need for malaria-specific interventions to save lives.

In parallel, WHO is working across the 3 levels of the organization to ensure that any advice intended to curb coronavirus transmission and to guide COVID-19 disease management is appropriate in malaria-affected settings.

In recent days, there have been reports of disruptions, as a result of COVID-19, in the production and global supply chains of essential malaria commodities, such as the long-lasting insecticidal nets, diagnostic testing and antimalarial medicines. Coordinated
efforts are required to ensure the availability of key malaria control tools – particularly in countries with a high burden of the disease – and that efforts to limit transmission of COVID-19 do not compromise access to malaria prevention,
diagnosis and treatment services.

Malaria-affected countries may also experience disruptions in health systems in the coming months. A marked increase in febrile patients seeking treatment for COVID-19 at health facilities, for example, would present a significant challenge for a health
workforce that may itself be depleted by the disease.

Policy guidance

WHO is developing guidance for national malaria control programmes and implementing partners to prepare them for the challenges they may face as result of COVID-19.  Among other areas, the guidance will address the mitigation of stockouts of
malaria medicines and commodities; the use of preventive malaria therapy for health workers; the deployment of emergency measures in some settings; and the generation of information relating to the geographic distribution and populations affected
by COVID-19 in malaria-endemic settings.

Restrictions around grouping people together – for training, social and behavior change communication activities, fixed-site distribution and clinical care – as well as the restrictions around movement of people in the country, will require
significant adaptations in order to deliver quality interventions and care.

All people living in malaria-affected areas are advised to follow same precautions as the general population, including: frequent hand-washing, respiratory hygiene, social distancing, seeking prompt medical care if symptoms arise (cough, fever,
difficulty breathing), and other WHO-recommended actions.

WHO stands ready to work with countries and other stakeholders to mitigate the negative impact of the coronavirus on malaria responses worldwide and, where possible, contribute towards a successful COVID-19 response.

About COVID-19

COVID-19 is the infectious disease caused by the most recently discovered coronavirus. This new virus and disease were unknown before the outbreak began in Wuhan, China, in December 2019. Essential information on the COVID-19 pandemic can be found in
a dedicated WHO site.

About malaria

Malaria is a preventable and treatable disease caused by parasites that are transmitted to people through the bites of infected female Anopheles mosquitoes. In 2018, there were an estimated 228 million cases of malaria worldwide and
405 000 malaria-related deaths. For more on malaria, visit: www.who.int/malaria

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https://www.who.int/news-room/detail/18-03-2020-who-teams-with-partners-to-mitigate-the-potential-impact-of-the-covid-19-pandemic-in-malaria-affected-areas

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March 19, 2020
Facebook Turns 10, Celebrates with Look Back and Paper for iPhone

Facebook, which has scripted a mammoth change in the way people interact, share and communicate with each other over the last decade, celebrated its tenth anniversary on February 4th. Nearly 1.23 billion users of the social networking site were in for a special surprise, thanks to Look Back, a feature that created a sentimental feel, as users were allowed to watch a movie of their lives, which included a collection of their most-liked status updates and photos…

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http://www.associationofmarketing.org/articles/view.php?article_id=14402

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March 18, 2020
3-D printers saving the lives of coronavirus victims

Medical valves manufactured with portable 3-D printers are saving the lives of coronavirus victims at a hospital located in what is considered Italy’s Ground Zero for the deadly viral infection.

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https://techxplore.com/news/2020-03-d-printers-coronavirus-victims.html

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March 17, 2020
Water and Climate Change
World Water Day 2020 is about water and climate change – and how the two are inextricably linked. This year’s campaign shows how our use of water will help reduce floods, droughts, scarcity and pollution, and will help fight climate change itself. By adapting to the water effects of climate change, we will protect health and save lives. And, by using water more efficiently, we will reduce greenhouse gases. Our key messages are clear:
- We cannot afford to wait. Climate policy makers must put water at the heart of action plans.
- Climate change effects water supplies and human health.
- Health systems need to prepare for more water-related disease associated with climate change.
- Water can help fight climate change and protect health. There are sustainable, affordable and scalable water and sanitation solutions.
- Everyone has a role to play. In our daily lives, there are surprisingly easy steps we can all take to address climate change, and protect health.
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https://www.who.int/news-room/detail/17-03-2020-water-and-climate-change

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March 17, 2020
Could we forgive a machine? Study explores forgiveness in the context of robotics and AI

As more robots make their way into society, it is important to consider the ethical and moral implications of having them complete tasks that can have a significant impact on people’s lives. If robots and machines are to become widely used in situations where they could seriously affect human lives, for instance by driving cars or giving elderly people the medication they need on a daily basis, developers should first consider the associated implications.

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March 12, 2020
The unmet need for social context in family planning

New evidence on the relationship between sexual health and social context finds a strong association between gender equality, education and family planning

Twenty-five years ago, two global events – the International Conference on Population and Development and the Fourth World Conference on Women in Beijing – formally recognized that women’s health and reproductive choices cannot be separated from the social context of their lives.

Now, researchers have created a dataset which brings together national surveys from 74 countries, representing 3 million women. For the first time, it allows them to describe trends in demand/use of modern contraceptives alongside social and economic indicators.

The data is published in The Lancet Global Health and is authored by the London School of Hygiene & Tropical Medicine and the World Health Organization.

It shows that, over time, women are more likely to have their demand for modern contraception met in countries where gender equality and their educational opportunities improve.

Gender equality and education increases access to modern contraception

Trends in sexual activity and demand for use and use of modern contraceptive methods in 74 countries: a retrospective analysis of nationally representative surveys finds that met need for modern contraception is strongly correlated with positive shifts in social structures.
For every 0.1-point increase in a country’s gender development index, it found a 6.7% rise in women who were sexually active and did not want to conceive. Of those women, an additional 13.5% used modern methods to prevent a pregnancy.

Expectations of every girl’s right to education also made a difference. Each extra year in schooling is linked to an increase of 2.3% in demand, and a 4.7% increase in use of modern contraceptive methods.

“This study shows how every woman must negotiate her reproductive autonomy within the social framework in which she lives, responding to barriers and opportunities as they emerge,” says Dr Lale Say, one of the authors of the study and Unit Head at WHO and HRP.

“Gender equality is both a precondition and a driving force for securing women’s reproductive health and rights – as well as the sustainable development targets, which are our best chance for delivering health and well-being for all.”

Global trends reveal new challenges in family planning

Overall, the data reinforce global trends: more time spent sexually-active and single, postponement of parenthood, and the near-universal desire for smaller families.

The study also highlights where action is needed at country-level to avoid family planning services falling behind demand.

Out of the 74 countries analyzed, 42 showed an increase in demand for contraception. Only 37 countries show an increase in use of a modern method to prevent pregnancy.

Although unmet need for contraception declined in 34 countries, it increased in 14 countries. Significantly more progress is needed, and faster, to ensure each girl and woman is able to access the sexual and reproductive health services she needs.

Barriers and solutions to reproductive health and rights

Gender equality can affect contraceptive use in many ways. From the personal and political degree to which women are free to choose their sexual activity, to accessing family planning services it can also shape any power imbalances within personal relationships. This study supports recent efforts by WHO to adopt a broader, integrated concept of sexual and reproductive health – and to translate it into a framework for policy and practice.

The authors argue that family planning targets in the 2030 Agenda for Sustainable Development will not be met without a profound shift: from focus on ‘access to contraception’, to broader aspects of sexual health and social context.

Since reproductive health and women’s empowerment are intertwined, trends in contraceptive use can also reveal progress towards another global target: progress towards gender equality.

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https://www.who.int/news-room/detail/10-03-2020-the-unmet-need-for-social-context-in-family-planning

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March 11, 2020
Cervical cancer elimination initiative updates

February: Garnering international support on the path to eliminate cervical cancer

On
5 February, the WHO Executive Board recommended to the 73rd World
Health Assembly the adoption of the draft Global Strategy to accelerate
the elimination of
cervical cancer as a public health problem, and urged its
implementation. The proposed resolution urges Member States to implement
the strategy, calling for the support of international organizations
and other relevant stakeholders, and includes a request
for the Director General to support Member states in this endeavor.
The WHA will consider the resolution when it convenes in May 2020. The
session included 23 interventions from EB Member States, most of them
in full support of the Strategy and resolution;
18 from other Member States, 6 observers and 6 non-state actors. Dr
Nono Simelela, ADG and Special Adviser to WHO Director-General Dr
Tedros, responded at the end of the session, thanking delegates for the
broad support, and addressing some of the comments
by sharing some of the ongoing work such as the efforts with the
immunization partners to address HPV vaccine supply challenges and
transparency in pricing.

Read the full story

Read the full draft resolution

Download the
Draft Strategy

Dr Nono Simelela presented the draft Global Strategy towards Eliminating Cervical Cancer as a Public Health Problem during a webinar with partners. This presentation was given as part of
the Us vs. HPV Prevention Week webinar series hosted by the Global
Initiative Against HPV and Cervical
Cancer. While highlighting WHO’s life-course approach to cervical
cancer control, Dr Simelela also explained the proposed elimination
threshold and targets as laid out in the strategy. She also discussed
addressing salient challenges such as redressing inequities
and taking special considerations for women living with HIV.

Read the full story

Listen to the full webinar “Gathering momentum for the global elimination of cervical cancer”

Watch the video: Cervical Cancer Elimination – developed by Basic Health International (BHI), Union for International Cancer Control (UICC) and the Global Initiative Against HPV and Cervical Cancer (GIAHC)

Read the story:To eliminate cervical cancer in the next 100 years, implementing an effective strategy is critical

Dr
Simelela was invited to Rwanda to support the kick off for a national
cervical screening program set to put Rwanda on the path towards the
Global Strategy goals
for elimination of cervical cancer.

Amongst
others, Rwanda’s First Lady Jeannette Kagame received her for a
discussion on how WHO can support efforts against cervical cancer in her
own country and
throughout Africa. Dr Simelela held discussions on cervical cancer
screening and treatment services, including building radiotherapy
capacity, with the dedicated staff of Ruhengeri Hospital, Butaro
Hospital, the Muhoza health center and hospital and the Rwanda
Military Hospital. While cervical cancer and breast cancer are the most
prevalent cancers among the women in the country, Rwanda has
impressively reached a 97% HPV vaccination rate since introducing a
vaccination programme in 2011, with a target to reach 70%
screening coverage in five years. We look forward to a continuing and
fruitful partnership with Rwanda and all the countries who have pledged
their commitment to eliminate this preventable cancer. Together we can
answer WHO’s call and improve the lives of
girls and women around the world.

Follow us for more updates!

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For
news and real-time updates from around the world,
follow Dr Princess Nono Simelela on Twitter
@DrNonoSimelela
ADG, Special Adviser to the Director-General on Strategic Programmatic Priorities

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https://www.who.int/news-room/detail/04-03-2020-cervical-cancer-elimination-initiative-updates-december-2019

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March 11, 2020