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Chagas disease: providing free paediatric medicine can enhance diagnosis and treatment
Documentation resulting in the donation of an important antiparasitic medicine for the treatment of Chagas illness to the World Health Organization (WHO) is within the ultimate stage of preparation.

A 3-year settlement, between the Mundo Sano Foundation¹ (Brazil) and WHO, is anticipated to make obtainable 108 000 tablets of the paediatric formulation of benznidazole² – a first-line medicine towards Chagas illness. Treatment³ with benznidazole within the early levels of an infection can treatment Chagas illness.

“Making benznidazole freely obtainable for the treatment of newborns till the age of 18 might be a game-changer within the battle towards Chagas illness” mentioned Dr Mwelece Ntuli Malecela, Director, WHO Department of Control of Neglected Tropical
Diseases. “This is not going to solely save future generations from growing life-threatening and deadly issues however can even increase up diagnosis and treatment.”

Each yr, an estimated 15 000 youngsters are born from contaminated moms. A freely obtainable paediatric presentation of benznidazole with correct dosage is essentially anticipated to contribute to deal with congenital infections.

“Treating newborns and youngsters was the lacking hyperlink, as we transfer decisively to advocate for the mixing of diagnosis of an infection amongst pregnant ladies and women of child-bearing age into different surveillance programmes, together with HIV and syphilis” mentioned Dr Pedro Albajar Vinas, Medical Officer with WHO’s Department of Control of Neglected Tropical Diseases. “Diagnosing and treating ladies of this age group earlier than being pregnant can increase successfully stop congenital transmission.”

The settlement

The donation by Mundo Sano Foundation at some point of the settlement includes benznidazole:
- 105,000 tablets of 100mg
- 3,000 tablets of 12.5mg
Furthermore, the Foundation might donate funds of as much as US$100 000 at some point of the settlement to help actions related to distribution of medicines and conferences. The Foundation additionally makes provision for an extension of this settlement past
the required length of three years.

The illness

Chagas illness, often known as American trypanosomiasis, is a doubtlessly life-threatening sickness brought on by the protozoan parasite Trypanosoma cruzi (T. cruzi).

Although appreciable progress has been achieved, significantly in decreasing vector transmission and screening of blood and organ provide, reaching and diagnosing individuals most affected has been a problem.

Currently, under-diagnosis of Chagas illness instances is as excessive as 90% and under-diagnosis of congenital transmission is believed to be even greater.

Globally, an estimated 6-7 million individuals are contaminated with T. cruzi.

The illness is discovered primarily in endemic areas of 21 continental Latin American international locations⁴. But motion of individuals to city areas and to different continents has expanded its transmission by means of non vectorial routes, akin to blood transfusion, congenital
transmission, organ transplants and oral meals contamination.

Considering the illness as a rising public well being drawback in lots of international locations, the World Health Assembly – WHO’s decision-making physique – determined in May 2019 to commemorate World Chagas Disease Day on 14 April.

The inaugural celebration occurs this yr.

¹Mundo Sano is a nonprofit worldwide basis working with the general public and personal sectors, academia, and different worldwide organizations to supply options to the affected communities and generate scientific information. In 2012, it led a public-private consortium in 2012 to provide benznidazole in Argentina.

²In 2017, the United States Food and Drug Administration (FDA) accepted benznidazole for the treatment of kids aged 2–12, making it the primary treatment accepted within the United States for Chagas illness.

³ Nifurtimox can be 100% efficient in curing Chagas illness if given quickly after onset of an infection, together with instances of congenital an infection. It is donated by Bayer who pledged greater than 7.5 million tablets for the interval 2012-2021.

⁴ Argentina, Belize, Bolivia (Plurinational State of), Brazil, Chile, Colombia, Costa Rica, Ecuador, El Salvador, French Guiana, Guatemala, Guyana, Honduras, Mexico, Nicaragua, Panama, Paraguay, Peru, Suriname, Uruguay, and Venezuela
(Bolivarian Republic of).

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April 3, 2020
WHO to accelerate action to reduce the harmful use of alcohol
The
harmful use of alcohol causes roughly Three million deaths yearly and the
general burden of illness and accidents attributable to alcohol consumption
stays unacceptably excessive. The tempo of improvement and implementation of
alcohol insurance policies has been uneven in WHO areas, and assets and capacities
for implementation of the WHO Global technique to reduce the harmful use of
alcohol 10 years after its endorsement don’t correspond to the magnitude of
the issues. On this foundation, the WHO Executive Board in its choice EB146
(14) known as for accelerated action to reduce the harmful use of
alcohol.

The Board thought of the report on the political declaration of the third high-level meeting of the General Assembly on the prevention and control of non-communicable diseases, notably Annex 3, entitled “Implementation of the global strategy to reduce the harmful use of alcohol,” and the report on the findings of the consultative process on implementation of the global strategy to reduce the harmful use of alcohol and the way forward.

The Board, in its choice EB146 (14), requested the WHO Director-General, inter alia, “to develop an action plan (2022-2030) to effectively implement the Global strategy to reduce the harmful use of alcohol as a public health priority, in consultation with Member States and relevant stakeholders, for consideration by the 75th World Health Assembly through the 150th session of the WHO Executive Board in 2022”, and “to develop a technical report on the harmful use of alcohol related to cross-border alcohol marketing, advertising and promotional activities, including targeting youth and adolescents, before the 150th session of the WHO Executive Board, which could contribute to the development of the action plan”, in addition to “to adequately useful resource the work on the harmful use of alcohol.

In response to choice EB146 (14), the WHO Secretariat will implement the following:
- March– April 2020: Commissioning of the scoping evaluate on the harmful use of alcohol associated to cross-border alcohol advertising and marketing, promoting and promotional actions, together with concentrating on youth and adolescents. Commissioning background papers for the report improvement.
- April-May 2020: Producing zero draft of the working doc for improvement of an action plan (2022-2030) to successfully implement the Global technique to reduce the harmful use with proposed important parts and parts.
- June 2020: Technical professional conferences organized by WHO headquarters to talk about zero draft of the working doc for improvement of the action plan and the content material of the technical report on the harmful use of alcohol associated to cross-border alcohol advertising and marketing, promoting and promotional actions.
- July-September 2020: Finalization of the working doc for subsequent session course of. Web-based session on the working doc for improvement of the action plan open to Member States, UN organizations and different worldwide organizations, and non-State actors. All related suggestions acquired will probably be revealed on WHO web site.
- October 2020 – March 2021: Regional technical consultations with Member States on the working doc for improvement of the action plan (2022-2030).
- March– April 2021: Development of the first draft of the action plan primarily based on the enter acquired on the working doc in the course of of the regional consultations.
- April -June 2021: The web-based session on the first draft of the action plan open to Member States, UN organizations and different worldwide organizations, and non-State actors. All related suggestions acquired will probably be revealed on WHO web site. Discussion of the first draft at the Third WHO Forum on alcohol, medication and addictive behaviours attended by technical focal factors from Member States, representatives of UN entities, civil society organizations, WHO collaborating centres, and academia. Consultation with financial operators in alcohol manufacturing and commerce on their contribution to decreasing the harmful use of alcohol inside their core roles. An casual session with Member States on the first draft of the action plan.
- July-August 2021: Development of the second draft of the action plan primarily based on the suggestions acquired on the first draft throughout the earlier levels of the session course of.
- August-November 2021: Briefings on the second draft of the action plan organized at the Regional Committee conferences. Release of the technical report on the harmful use of alcohol associated to cross-border alcohol advertising and marketing, promoting and promotional actions, together with concentrating on youth and adolescents, with a abstract of fundamental findings and conclusions out there in six languages. A proper assembly of Member States for consideration of the second draft of the action plan. Finalization of the draft action plan considered suggestions and inputs acquired from Member States and different stakeholders throughout the session course of in April -October 2021. Development and submission of the report by the Secretariat to 150th session of the Executive Board.
- January/February 2022: The 150th session of the WHO Executive Board will think about the report of the WHO Director-General containing the draft action plan (2022-2030) to successfully implement the Global technique to reduce the harmful use of alcohol.
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April 3, 2020
Petri Dish Detention By Mohammed Ibraheem Zakzaky

The world is gripped in the Coronavirus reality and the immense panic and disruption it brings along with it. This virulent scourge has cut a path less trodden by viruses, as it infects and spreads with little regard for all the norms of red tape that has allowed the murder and official disappearance of many, including my six brothers. By the time it begins to execute those whose death sentences it has written and signed it is always 10 steps ahead on the paperwork. That is almost eight steps ahead of professionals like Buhari.

The virus is a near perfect beta of a doomsday virus. Even the most hard-line sceptics have ended up dumbfound by just how profoundly serious Covid-19 is as a survivalist organism that is here to accomplish its apocalyptic mission. Though many medical experts have since been pressured, pressed and forced to promise a vaccine and possible cure within the next few months to a year; the truth is that the threat is clearly unprecedented.

In my case I went to sleep in a world where my priority was to deliver food and medical aid to my parents in Kaduna Prison; only to wake up and realize that there was an even larger number of factors in play. I slept knowing full well that it was an uphill battle against the entire regime of Major-General-Buhari and his army of punitive henchmen; to all of a sudden be confronted by a Diablo ex-Machina; courtesy of the novel corona virus AKA Covid-19.

Now all visits to prison by anyone and everyone were effectively and strictly forbidden. I understood and reasoned that it was the proper measure to prevent contagion of this clearly deadly disease. The last thing I would want is to be a part of what makes my already sickly parents sicker; or worse.

In spite of the fact that I had completed all arrangements to have doctors visit both my parents in Kaduna Prison, in order to provide them with relief for their existing medical conditions due to age and a plethora of wounds they sustained during the attack and subsequent ransacking of our home by the Nigerian Army. All of which have all gone untreated during the past five years.

I still thought and reasoned that a quarantine of the entire area was the best measure possible in the short term, considering the existing circumstances. As a result of this I made all the necessary apologies to cancel appointments with all the doctors and hospitals, to ensure that the quarantine in Kaduna Prison will hold and be maintained. I then did all in my power to send masks, hand sanitizers, gloves, soap and vitamins. All in an effort to stay safe and keep everyone safe.

I have now since been jolted out of the stupor of perceived safety by terrible news. There has been a violent incident inside Kaduna Prison, which has rendered my memory of the Zaria Massacre of 2015 raw. As the harrowing sounds of another rampage of gun fire was heard from Kaduna Prison, where my parents are currently being detained.

All my frantic calls to the Controller of Prisons and his deputy were not answered, as the sounds of gun fire continued to rage. All my efforts to learn what was really going on failed. I have however been able to learn a few things through the few answered calls. All of them agree on the following.

1.      There has been a surge of Covid-19 symptomatic prisoners in Kaduna Prison.

2.      Staff of the prison clinic have been avoiding three symptomatic prisoners particularly.

3.      Three of them were removed and one was returned on Tuesday.

4.      A number of Prisoners strongly objected to the re-introduction of the prisoners.

5.      The prison staff tried to calm things down by trying to reason with them.

6.      The Prison’s armed squad were then deployed, to supress an alleged prison break.

7.      After a period of automatic fire in the air and on target, calm was restored.

8.      The prisoners suspected of Covid-19 are among those reported shot and killed.

9.      Bullet canisters were still littered all over the place 3 hours later.

10. Many of the Kaduna prison staff are visibly injured, some with serious injuries.

11. A significant number of the injured staff were seen walking around in blood-soaked uniforms.

12. So called normalcy has been enforced, and returned at an unknown cost.

The fact remains that the highly crowded, unsanitary conditions of Kaduna Prison remains a highly contagious environment, that is no place for my vulnerable mother and father, both of whom are above 50 years of age. Both of whom are un-healthy, both of whom are suffering from an unprecedented number of health issues that have remained untreated and unattended.

Due to a determination by the regime of Heil! Major-General Buhari and his now contagious Governor El-Rufai and their army of undertakers. It is unclear what is really going on at the site of all the intense gunfire that was heard in Kaduna Prison. Aside from the above stated facts, I can say no more.

Opinion

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April 2, 2020
OHCHR, IOM, UNHCR and WHO joint press release: the rights and health of refugees, migrants and stateless must be protected in COVID-19 response

In the face of the COVID-19 crisis, we are all vulnerable. The virus has shown that it does not discriminate – but many refugees, those forcibly displaced, the stateless and migrants are at heightened risk.

Three-quarters of the world’s refugees and many migrants are hosted in developing regions where health systems are already overwhelmed and under-capacitated. Many live in overcrowded camps, settlements, makeshift shelters or reception centers, where they lack adequate access to health services, clean water and sanitation.

The situation for refugees and migrants held in formal and informal places of detention, in cramped and unsanitary conditions, is particularly worrying. Considering the lethal consequences a COVID-19 outbreak would have, they should be released without delay. Migrant children and their families and those detained without a sufficient legal basis should be immediately released.

This disease can be controlled only if there is an inclusive approach which protects every individual’s rights to life and health. Migrants and refugees are disproportionately vulnerable to exclusion, stigma and discrimination, particulary when undocumented. To avert a catastrophe, governments must do all they can to protect the rights and the health of everyone. Protecting the rights and the health of all people will in fact help control the spread of the virus.

It is vital that everyone, including all migrants and refugees, are ensured equal access to health services and are effectively included in national responses to COVID-19, including prevention, testing and treatment. Inclusion will help not only to protect the rights of refugees and migrants, but will also serve to protect public health and stem the global spread of COVID-19. While many nations protect and host refugee and migrant populations, they are often not equipped to respond to crises such as Covid-19. To ensure refugees and migrants have adequate access to national health services, States may need additional financial support. This is where the world’s financial institutions can play a leading role in making funds available.

While countries are closing their borders and limiting cross-border movements, there are ways to manage border restrictions in a manner which respects international human rights and refugee protection standards, including the principle of non-refoulement, through quarantine and health checks.

More than ever, as COVID-19 poses a global threat to our collective humanity, our primary focus should be on the preservation of life, regardless of status. This crisis demands a coherent, effective international approach that leaves no-one behind. At this crucial moment we all need to rally around a common objective, fighting this deadly virus. Many refugees, displaced, stateless people and migrants have skills and resources that can also be part of the solution.

We cannot allow fear or intolerance to undermine rights or compromise the effectiveness of responses to the global pandemic. We are all in this together. We can only defeat this virus when each and every one of us is protected.

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April 1, 2020
How to Use Video Effectively

Video has emerged as one of the most popular marketing tools available in recent years, with the potential results of a skillfully developed marketing video making marketers salivate. Web users regularly interact with video content on the Internet, with viral videos spreading around the world at rapid speed, pulling in views that can easily translate into big sales potential. While creating the next viral hit might feel like a challenge, there are several techniques that can help demystify the video creation process. Use the following tips to ensure a marketing video is well-targeted and effective at reaching consumers…

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March 31, 2020
WHO releases guidelines to help countries maintain essential health services during the COVID-19 pandemic

The COVID-19 pandemic is straining health systems worldwide. The rapidly increasing demand on health facilities and health care workers threatens to leave some health systems overstretched and unable to operate effectively.

Previous outbreaks have demonstrated that when health systems are overwhelmed, mortality from vaccine-preventable and other treatable conditions can also increase dramatically. During the 2014-2015 Ebola outbreak, the increased number of deaths caused
by measles, malaria, HIV/AIDS, and tuberculosis attributable to health system failures exceeded deaths from Ebola
^[1,2].

“The best defense against any outbreak is a
strong health system,” stressed WHO Director-General Tedros Adhanom Ghebreyesus.
“COVID-19 is revealing how fragile many of the world’s health systems and
services are, forcing countries to make difficult choices on how to best meet
the needs of their people.”

To help countries navigate through these challenges, the World Health Organization (WHO) has updated operational planning guidelines in balancing the demands of responding directly to COVID-19 while maintaining essential health service delivery, and mitigating
the risk of system collapse. This includes a set of targeted immediate actions that countries should consider at national, regional, and local level to reorganize and maintain access to high-quality essential health services for all.

Countries should identify essential services that will be prioritized in their efforts to maintain continuity of service delivery and make strategic shifts to ensure that increasingly limited resources provide maximum benefit for the population. They
also need to comply with the highest standard in precautions, especially in hygiene practices, and the provision of adequate supplies including personal protective equipment This requires robust planning and coordinated actions between governments
and health facilities and their managers.

Some examples of essential services include: routine vaccination; reproductive health services including care during pregnancy and childbirth; care of young infants and older adults; management of mental health conditions as well as noncommunicable diseases
and infectious diseases like HIV, malaria and TB; critical inpatient therapies; management of emergency health conditions; auxiliary services like basic diagnostic imaging, laboratory services, and blood bank services, among others.

Well-organized and prepared health systems can continue to provide equitable access to essential service delivery throughout an emergency, limiting direct mortality and avoiding increased indirect mortality.

The guidelines stress the importance of keeping up-to-date information. This requires frequent transparent communications with the public, and strong community engagements so the public can maintain trust in the system to safely meet their
essential needs and to control infection risk in health facilities. This will help ensure that people continue to seek care when appropriate, and adhere to public health advice.

1. Elston, J. W. T., Cartwright, C., Ndumbi, P., & Wright, J. (2017). The health impact of the 2014–15 Ebola outbreak. Public Health, 143, 60-70.

2. Parpia, A. S., Ndeffo-Mbah, M. L., Wenzel, N. S., & Galvani, A. P. (2016). Effects of response to 2014–2015 Ebola outbreak on deaths from malaria, HIV/AIDS, and tuberculosis, West Africa. Emerging infectious diseases, 22(3), 433.

For interviews please contact: Tarik Jasarevic

To access the full guidance please visit: https://www.who.int/emergencies/diseases/novel-coronavirus-2019/technical-guidance/maintaining-essential-health-services-and-systems

For further information and guidance on COVID-19 please visit: https://www.who.int/emergencies/diseases/novel-coronavirus-2019

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March 31, 2020
Tips for Developing an Effective Black Friday Marketing Campaign

Black Friday is traditionally said to be the day that retailers start turning a profit for the year. The term refers to the retailer?s bottom line going from red to black, and it is the day the holiday shopping season unofficially starts. Therefore, it?s important to market Black Friday?s discounts and sales effectively. Everything from the timing of the release of the ad to the time the store opens can affect the customer turnout on Black Friday.

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March 30, 2020
How to Effectively Market to the Growing Hispanic Segment

America is fast embracing multiculturalism, and the changing dynamics have produced new dilemmas for the various marketers who are required to reach the people whose language, customs, and tastes aren’t the same as the ?general market?. It will become more critical to have marketing plans that are culturally relevant as the diversity in the population increases and ethnic minorities such as the U.S. Hispanics gain more prominence. The present-day market trend makes it imperative for the marketers to analyze and adopt novel strategies in the same manner that they’ve allocated the corporate marketing resources through time, in order to use marketing to Hispanics to their advantage…

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March 27, 2020
Using SlideShare to Generate Leads

Visual content marketing is motivating marketers to rethink their overall marketing strategy. Previously, written content was enough to make the marketing strategy of many business work effectively. However, it isn?t enough anymore. Now, it takes more than that to get the message to existing and prospective clients…

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March 26, 2020
Do not take RTK test for Covid-19 without doctor’s advice: MOH

KUALA LUMPUR: The Health Ministry (MOH) has called on the people not to undergo rapid test kit (RTK) tests arbitrarily without seeking the advice of medical practitioners.

Health director-general, Datuk Dr Noor Hisham Abdullah (pix) said it has the potential to a give wrong interpretation from the result obtained.

“The test via RTK technique which is now available in the market is to detect antibodies produced by the body as a result of an infection. The antibodies will appear in the body in five to eight days after infection.

“The RTK test which detects antibodies, cannot detect virus and it is administered for quick confirmation. As such it cannot help in the detection of initial Covid-19 cases. Therefore, RTK test is not recommended for diagnosing Covid-19,” he said in a statement today.

Elaborating further, Dr Noor Hisham said MOH is using the Real-Time Reverse Transcription Polymerase Chain Reaction (rRT-PCR) technique at government health laboratories to detect the presence of Covid-19 virus found in the body of patients.

If the rRT-PCR COVID19 test is found positive, it means the individual has been infected by Covid-19 virus.

“The result of the rRT-PCR technique is very important in managing Covid-19 patients effectively,” he said.

In this regard, Dr Noor Hisham advised the people not to discriminate members of the tabligh congregation following the spread of Covid-19 from the cluster and should in fact assist MOH in tracing close contacts among them.

“We should not blame tabligh members, do not discriminate them, we should not stigmatise the tabligh congregation. What is important is for us to assist, trace and treat Covid-19 infection among tabligh members, their families and their contacts,” he said.

Apart from that. Dr Noor Hisham said KKM is cooperating with MERCY Malaysia to provide psychosocial support to the people especially frontliners and individuals emotionally affected by Covid-19.

They can obtain the service by contacting 011-63996482 / 011-63994236 / 03-29359935 from 8am to 5pm daily.

Members of the public can also contact the virtual health advisory team for a webinar session daily from 9am onwards at http://www.doctoroncall.com.my/coronavirus. – Bernama

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March 24, 2020