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Making available free paediatric medicine can accelerate elimination of congenital Chagas disease
The donation of an essential antiparasitic medicine can potentially accelerate the elimination of Chagas disease infection in children. A pediatric presentation of benznidazole with accurate dosage and will soon be made available freely to address
a long-standing gap in the treatment of congenital infections of Chagas disease.

The donation, by the Mundo Sano Foundation¹ and INSud Pharma² group to the World Health Organization (WHO), is expected to become effective soon.

“Making benznidazole freely available for the treatment of newborns and children until the age of 19 will be a game-changer in the fight against Chagas disease” said Dr Mwelecele Ntuli Malecela, Director, WHO Department of Control
of Neglected Tropical Diseases. “This can save future generations from developing life-threatening and fatal complications and also boost up diagnosis and treatment contributing to congenital Chagas disease elimination.”

The three-year agreement will make available 108 000 tablets of benznidazole³ – one of the two antiparasitic medicines against Chagas disease. Treatment⁴ with benznidazole in the early stages of infection can cure Chagas
disease, prevent or curb disease progression and prevent congenital transmission in pregnant women.

“We have now added the systematic detection and treatment of all newborns and children under 19 which was not part of our recent switch from control to elimination of congenital Chagas disease” said Dr Pedro Albajar
Vinas, Medical Officer, WHO Department of Control of Neglected Tropical Diseases. “In addition, screening of pregnant women at risk of infection who have not had past antiparasitic treatment provides an excellent opportunity for prevention of posterior transmission throughout pregnancy and birth.”

Each year, an estimated 15 000 children are born from infected mothers.

The agreement

The donation by Mundo Sano Foundation for the duration of the agreement comprises benznidazole:
- 105,000 tablets of 100mg
- 3,000 tablets of 12.5mg
Furthermore, the Foundation may donate funds to support activities associated with distribution of medicines and is ready to consider extending this agreement beyond the specified duration of three years.

The disease

Chagas disease, also known as American trypanosomiasis, is a potentially life-threatening illness caused by the protozoan parasite Trypanosoma cruzi (T. cruzi).

Although considerable progress has been achieved, particularly in reducing vector transmission and screening of blood and organ supply, reaching, diagnosing and providing healthcare for people most affected has been a challenge.

Currently, under-diagnosis of Chagas disease cases is as high as 90% and under-diagnosis of congenital and paediatric cases is believed not to be lower.

Globally, an estimated 6-7 million people are infected with T. cruzi.

The disease is found mainly in endemic areas of 21 continental Latin American countries⁵. But movement of people to urban areas and to other continents has expanded its transmission through non vectorial routes, such as blood transfusion,
congenital transmission, organ transplants and oral transmission through food contamination.

Considering that neglected tropical disease as a growing public health problem in many countries, the World Health Assembly – WHO’s decision-making body – decided in May 2019 to commemorate World Chagas Disease Day on 14 April.

The inaugural celebration happens this year.

¹Mundo Sano is a nonprofit international foundation working with the public and private sectors, academia, and other international organizations to provide solutions to the affected communities and generate scientific knowledge.
In 2012, it led a public-private consortium in 2012 to produce benznidazole in Argentina.

²Insud Pharma (formerly known as Chemo Group) specializes in research, development, manufacture, sale and marketing of active pharmaceutical ingredients and medicinal products for human and veterinary use.

³In 2017, the United States Food and Drug Administration (FDA) approved benznidazole for the treatment of children aged 2–12, making it the first treatment approved in the United States for Chagas disease.

⁴Nifurtimox is also 100% effective in curing Chagas disease if given soon after onset of infection, including cases of congenital infection. It is donated by Bayer who pledged more than 7.5 million tablets for the period 2012-2021.

⁵Argentina, Belize, Bolivia (Plurinational State of), Brazil, Chile, Colombia, Costa Rica, Ecuador, El Salvador, French Guiana, Guatemala, Guyana, Honduras, Mexico, Nicaragua, Panama, Paraguay, Peru, Suriname, Uruguay, and Venezuela
(Bolivarian Republic of).

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April 8, 2020
National Ethics Committees and COVID-19

On
Monday April 6, WHO will host a digital assembly to facilitate communication,
collaboration and alternate between National Ethics Committees from across the
world to assist international locations reply to the moral challenges offered by
COVID-19. This assembly will likely be chaired by Hugh Whittall from the Nuffield
Council on Bioethics.

Related sources

A selection of work addressing the COVID-19 pandemic

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April 5, 2020
Nigeria’s Coronavirus Cases Rise To 131

The variety of confirmed instances of Coronavirus in Nigeria rose to 131 on Monday with two recorded deaths.

Nigerian Centre for Disease Control made the announcement

The NCDC tweeted, “Twenty new instances of #COVID19 have been reported in Nigeria; 13 in Lagos, 4 in FCT, two in Kaduna and one in Oyo State.

“As of 09:00pm on March 30, there are 131 confirmed instances of #COVID19 reported in Nigeria with two deaths.

“For a breakdown of cases by states in real-time, Lagos currently has 81 cases, FCT- 25, Ogun- three, Enugu- two, Ekiti- one, Oyo- eight, Edo- two, Bauchi- two, Osun – two, Rivers – one, Benue – one, and Kaduna also has three.”

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April 5, 2020
President Buhari Succumbs To Public Pressure, Signs COVID-19 Regulations 2020

After intense strain from the Nigerian public particularly from senior authorized practitioners and different outstanding residents, President Muhammadu Buhari on Monday introduced the signing into legislation of the COVID-19 Regulations.

Sections 2, Three and four of the Quarantine Act (CAP Q2 LFN 2004) conferred such powers on President Buhari.

It was the authorized framework wanted to implement the lockdown order in Lagos, Ogun and the FCT issued by Buhari on Sunday throughout a nationwide broadcast.
The announcement was made on Monday evening by Special Adviser to President Buhari on Media and Publicity, Femi Adesina.

President Buhari had addressed Nigerians on the outbreak and continued unfold of Coronavirus 35 days after the nation’s first case was recorded.

A flurry of criticisms over his silence and perceived lack of concern on the harm attributable to the pandemic had pushed him to talk.

Recall that earlier on Monday, Senior Advocate of Nigeria, Femi Falana, had mentioned that the lockdown order couldn’t be enforced besides it was backed by a legislation.

He mentioned, “No doubt, the President is empowered to undertake any measure deemed match to fight the damaging illness however such measure must be spelt out in a Regulation made pursuant to part 305 of the structure or beneath the Quarantine Act.

“Otherwise the presidential order on restriction of movement in the affected areas cannot be enforced by the police.”

Another lawyer, Inibehe Effiong, whereas reiterating Falana’s place, in truth vowed to problem the illegality of Buhari’s motion in court docket.

He mentioned, “After a deep reflection on President Muhammadu Buhari’s resolution to lock down all actions in Lagos, Ogun and Abuja by presidential fiat for 14 days, I’ve resolved to problem this unconstitutional motion in court docket.

“No accountable, democratic and civilised nation will throw its structure and legal guidelines into the dustbin in an effort to sort out a pandemic like COVID-19 the way in which President Buhari has carried out. Freedom of motion is a elementary proper assured by Section 41 of the structure.

“While it’s conceded that this proper just isn’t absolute, Section 45 of the structure is evident to the impact that freedom of motion can solely be taken away within the method allowed by a legislation that’s moderately justifiable in a democratic society. Buhari has not relied on any legislation.

“If Buhari is convinced that extraordinary measures are needed to contain Coronavirus, the proper action would have been for him to issue an instrument published in the official gazette of the government and make a proclamation of a state of emergency in Lagos, Ogun and Abuja.”

Also including his voice to the difficulty earlier on Monday, Nobel Laureate, Prof Wole Soyinka, mentioned that President Buhari had no constitutional backing to declare a complete lockdown of Lagos, Ogun and Abuja.

He mentioned, “The worst development I can conceive is to have a situation where rational measures for the containment of the Corona pandemic are rejected on account of their questionable genesis.
“So, earlier than this turns into a behavior, a query: does President Buhari have the powers to shut down state borders? We need clear solutions. We should not in a struggle emergency.
“We need to exercise collective vigilance, and not compromise the future by submitting to interventions that are not backed by law and constitution.”

However, earlier defending Buhari’s declaration of a lockdown in all three cities, Nigeria’s Attorney-General of the Federation, Abubakar Malami, mentioned that the President didn’t want any particular authorized framework to have the order enforced because the Quarantine Act already coated that.

Malami mentioned, “The appropriate place stays that the President acted rightfully beneath the powers conferred on him by the Quarantine Act 1990 CAP 384 LFN.

“Section 3 of the Act enables the President to declare any part of Nigeria as an infected area. Section 4 of the Act further empowers the President to make regulations to prevent the introduction, spread and transmission of any dangerous infectious disease.”

But with Buhari’s newest transfer on Monday, Malami now stands alone on the matter.

Enforcement of the order is now anticipated to begin in Lagos and FCT whereas it would take impact in Ogun from April 3.

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April 5, 2020
COVID-19: Delta Government Raises Concerns Over Neighbouring States Yet To Close Borders

Governor of Delta State, Ifeanyi Okowa

Governor of Delta State, Ifeanyi Okowa

As the unfold of the dreaded Coronavirus illness continues, the Delta State Government has raised issues over neighbouring states but to shut their borders.
Addressing journalists over the problem on Monday, Commissioner for Information in Delta, Charles Aniagwu, stated, “Our neighbouring states are yet to close their borders and this poses a serious danger to us in Delta.

“If Anambra and Edo are but to shut their borders and Delta has performed that, it poses hazard to us.

“The Federal Government should order the shutting down of the nation to avoid more infections as far as the COVID-19 is concerned.

“We are interesting for cooperation particularly from most of the people. Let’s all comply strictly to the security measures outlined to this point.”

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April 5, 2020
Breakdown of Funds Donated to Federal and State Governments in the Fight Against the Coronavirus.

As the Nigerian Government intensifies efforts in its battle towards Coronavirus, monetary donations have continued to pour in from each sector to help the battle.

High-profile Nigerians and politicians have additionally donated mouth-watering sums to authorities at the federal and state ranges to fight the virus.

Others like ex-President Olusegun Obasanjo supplied properties to be used as isolation centres and well being supplies for therapy of contaminated circumstances.

In complete, 22 donors have supported the battle to eradicate the virus from the nation.

So far, each the federal and state governments have obtained the sum of N40,771,000,000 as donation to the venture.

In a breakdown of the funds, the federal authorities led the marketing campaign with a donation of N10bn grant to Lagos State and N5bn to the Nigerian Centre for Disease Control, the company main the battle towards the virus.

While Tony Elumelu of United Bank for Africa donated N5bn to the authorities, Keystone Bank, Segun Agbaje of Guaranty Trust Bank, and Jim Ovia of Zenith Bank donated N1bn every.

Noteworthy of the donation is the Nigerian National Petroleum Corporation that donated N11bn to the authorities.

The donation raised previous considerations on the non-remittance of full income by the NNPC to the Nigerian Government.

The desk beneath exhibits a full breakdown of funds donated to federal and state governments in the battle towards the virus.

Breakdown of Funds Donated to Federal and State Governments in the Fight Against the Coronavirus. by Sahara Reporters on Scribd

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April 5, 2020
There probably isn’t as much fake news in the media as we think

An evaluation of the media consumption habits of individuals in the US reveals that fake news makes up a tiny fraction of what they watch or learn daily

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April 4, 2020
WHO and UNICEF to partner on pandemic response through COVID-19 Solidarity Response Fund
WHO and UNICEF as we speak introduced an settlement to work collectively on COVID-19 response, through the historic COVID-19 Solidarity Response Fund powered by the United Nations Foundation and Swiss Philanthropy Foundation.

The COVID-19 Solidarity Response Fund has been arrange to facilitate an unprecedented world response by supporting the WHO Strategic Preparedness and Response Plan. As a part of the settlement, an preliminary portion of the cash from
the Fund – which presently stands at greater than $127 million – will circulate to UNICEF for its work with susceptible kids and communities everywhere in the world.

“COVID-19 is an unprecedented pandemic requiring extraordinary global solidarity to urgently respond,” stated Dr Tedros Adhanom Ghebreyesus, WHO Director-General. “I’m happy that UNICEF joined the Solidarity
Response Fund. With their in depth expertise each in fundraising and in implementing programmes, this partnership will assist us to work collectively carefully to save lives.”

The cash collected through the fund can be used, amongst others, to practice and equip communities and health-care staff to forestall, detect and deal with COVID-19. It will assist international locations broaden their health-care capability and mitigate its social impression, particularly
on girls, kids and susceptible social teams. And it should speed up analysis and improvement of therapies and preventive vaccines.

As a key partner on this joined-up effort, UNICEF will lead emergency efforts to guarantee households and communities in probably the most susceptible international locations are totally engaged within the response and have entry to water, sanitation and hygiene and different an infection prevention
and management measures. UNICEF may even guarantee kids, caretakers, and frontline responders corresponding to social staff, academics and healthcare staff are supported through evidence-based steering through its huge group outreach and nation
packages.

“This is an extraordinary emergency that demands an extraordinary response, and we need all-hands on deck—individuals, corporations, foundations, governments and other organizations around the world,” stated UNICEF Executive Director Henrietta
Fore. “UNICEF is happy to be a part of the Solidarity Response Fund. It will bolster our efforts to strengthen well being and sanitation techniques and assist shield probably the most susceptible households from knock-on impacts of COVID-19 on already overstretched well being
techniques.”

Funds raised can be spent in alignment with the worldwide response plan, and the place wants are biggest. At the path of WHO management, it’s anticipated that sources will go immediately towards:
- WHO, for its work to monitor the unfold of the virus, assess gaps and wants, equip frontline well being staff with private protecting gear, guarantee lab and testing instruments can be found in international locations around the globe, and maintain communities
  and frontline responders knowledgeable with the most recent technical steering.
- UNICEF, to guarantee kids and households around the globe are outfitted with all of the evidence-based data and newest WHO steering in addition to domestically related data to shield themselves from the unfold of COVID-19; to assist
  susceptible international locations by offering entry to water, sanitation and hygiene, and primary an infection prevention and management measures; and to present entry to look after susceptible households and kids.
- CEPI, the Coalition for Epidemic Preparedness Innovations, a key partner main the financing for analysis and improvement for novel vaccines to fight COVID-19, working carefully with WHO.
The COVID-19 Solidarity Response Fund was arrange at WHO’s request by the UN Foundation and Swiss Philanthropy Foundation and launched three weeks in the past. It is the one manner for people and organizations to contribute immediately to WHO’s
world efforts to deal with the pandemic. To date the fund has $127 million raised or dedicated from greater than 219,000 people from everywhere in the world plus greater than 90 world corporations and organizations. The partnership can be an amazing
demonstration of solidarity throughout UN organizations in coordinating, partnering and supporting one another in coping with the instant and longer-term impression of the pandemic.

“There has never been a more urgent need for global cooperation,” stated Elizabeth Cousens, President & CEO of the UN Foundation. “The COVID-19 pandemic reveals us that all of us can play a component to cease the unfold. The unimaginable
generosity proven to the COVID-19 Solidarity Response Fund from around the globe will assist WHO, UNICEF, CEPI and companions speed up their lifesaving work, particularly to assist probably the most susceptible communities and velocity the event of a
vaccine.”

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Notes to editors

About UNICEF

UNICEF works in a few of the world’s hardest locations, to attain the world’s most deprived kids. Across greater than 190 international locations and territories, we work for each little one, in every single place, to construct a greater world for everybody.

About WHO

WHO is the United Nations’ specialised company for well being. It is an inter-governmental group and works in collaboration with its Member States often through the Ministries of Health. The World Health
Organization is accountable for offering management on world well being issues, shaping the well being analysis agenda, setting norms and requirements, articulating evidence-based coverage choices, offering technical assist to international locations and monitoring
and assessing well being tendencies. Learn extra at www.who.int.

About the United Nations Foundation

The UN Foundation brings collectively concepts, folks, and sources to assist the United Nations drive world progress and deal with pressing issues. Our hallmark is to collaborate for lasting change and innovate to handle humanity’s biggest challenges.
Learn extra at www.unfoundation.org.

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April 4, 2020
Digital technology for COVID-19 response
WHO has acquired overwhelming pro-bono help from technology firms to struggle the COVID-19 pandemic. On 2 April, 30 of the world’s main digital technology specialists gathered in a digital roundtable to assist advance WHO’s collaborative response to COVID-19.

This pandemic has triggered an unprecedented demand for digital well being technology options and has revealed profitable options corresponding to for inhabitants screening, monitoring the an infection, prioritizing the use and allocation of sources, and designing focused responses.

“We want your dedication, so we will flip these concepts into actuality and work with public well being companies and frontline well being employees to place this pandemic to relaxation,” stated WHO Director-General, Dr. Tedros Adhanom Ghebreyesus, in his welcoming comment. “We can solely sort out this world menace – and get our financial system again on observe – by working collectively.”

The assembly was co-facilitated by Steve Davis and Precious Malebona Matsoso, co-chairs of WHO Digital Health Technical Advisory Group.

The targets of the assembly have been as follows:
1. Introduce WHO’s Digital Health & Innovation efforts for COVID-19 and search help from technology firms within the design and execution of these initiatives.
2. Build on WHO’s COVID-19 efforts by way of new collaboration and data sharing, to ship focused options by way of a coordinated effort to help international locations dealing with phases of this epidemic in numerous methods and totally different instances.
3. Share and discover identified gaps and areas that lack focus. Topics embody user-focused options, combating misinformation, provide chain administration, functions supporting well being employees, neighborhood engagement platforms, help data administration capacities, analysis and improvement help, restoration planning work.
4. Secure volunteer and pro-bono sources from world tech firms to design and execute response initiatives with WHO.
Bernardo Mariano Junior, director of WHO’s Department of Digital Health and Innovation, known as for unity in response efforts, “The world must be properly ready and united within the spirit of shared accountability, to digitally detect, shield, reply, and put together the restoration for COVID 19. No single entity or single nation initiative will likely be enough. We want everybody.”

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April 4, 2020
BREAKING: Nigerian Army Arrests Personnel In Viral Video Threatening To Rape, Infect Women With HIV In Warri After SaharaReporters’ Story

The Nigerian Army has arrested two of its troopers, who threatened to rape and infect ladies in Warri, Delta State, with HIV in retaliation for the alleged killing of their colleague.

The slain soldier was alleged to have been killed by a mob after he shot lifeless a person named Joseph Pessu in Warri on Thursday.

Pessu’s killing led to protest by indignant residents of Ugbuwangue, a suburb of Warri, who blocked main roads and burnt tyres to precise their ache.

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Protest Erupts In Delta Over Killing Of Man By Army Personnel

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In the 26-second lengthy video, the 2 arrested troopers sweared on the individuals of Warri and promised them a tormenting expertise for daring to take the lifetime of their colleague.

Speaking in disjointed Pidgin, one of many troopers stated, “Warri individuals, una don purchase job o. Una kill soldier ba? Your moms, I’ll ensure that I f..ok your moms pores and skin to pores and skin with out condom.

“I’ll ensure that she carry HIV, your daughters will carry HIV, your wives will carry HIV.

“You get mind to kill soldier ba? Dan ubanku.”

VIDEO: Nigerian Soldiers Threaten To Rape Women In Warri, Infect Them With HIV In Retaliation For Killing Colleague @HQNigerianArmy #CoronavirusLockdown #LockDownNigeria #COVID19 #Coronavirus pic.twitter.com/7gsozO3lXb

— Sahara Reporters (@SaharaReporters) April 3, 2020

But reacting to the difficulty in a press release on Friday, the Nigerian Army stated the lads had been arrested at 9 Brigade, Ikeja Military Cantonment, Lagos, including that additional investigations had been ongoing.

The assertion reads, “Soldiers in a viral video utilizing uncouth and uncivilised language purportedly threatening to molest ladies in Warri, Delta State, had been arrested at 9 Brigade, Ikeja Military Cantonment, Lagos State, right now 3 April, 2020 and additional investigation is ongoing.

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Panic In Warri As Nigerian Army Personnel Threaten To Rape, Infect Women With HIV After Death Of Colleague

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“The common public must be assured that the investigations might be swift and truthful in accordance with relevant navy legal guidelines.

“The final result of the investigations will decide essentially the most acceptable disciplinary measures that may be taken within the circumstances.

“The Nigerian Army wishes to reiterate that it would not tolerate any form of irresponsibility and indiscipline on the part of any of its personnel.”

The Nigerian Army place rubbishes an earlier denial by the Delta State Government, who described the video first printed by SaharaReporters as “fake”.

Commissioner for Information within the state, Charles Aniagwu, had stated that the video was concocted and created by disgruntled components bent on pitching the individuals towards the state authorities.

But with the newest improvement, it’s clear info prevailed over sentiment.

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April 4, 2020