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  • Cure Your Acne By Adopting a Vegan Diet

    Cure Your Acne By Adopting a Vegan Diet

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    If you are reading this article you are getting closer to finding the causes of your acne. I am glad that you might want to try to cure your acne by adopting a vegan diet.

    I tell you that simply going vegan might not be the entire answer you are looking for. The reason that I tell you this is because the term "Vegan" is a very general term that simply means that the food is free from animal products.

    Adopting a vegan diet that only consist of non toxic, non allergenic, and good for your specific genetics will definitely help to cure your acne. The thing is, is that there are many acne causing foods and ingredients that are vegan.

    To give you an example of things that are considered vegan, but that will cause your acne to get even worse will include, Table salt. hydrogenated oil. food additives, food colorings, and anything that your body is allergic to.

    Also one of the foods that makes me break out with acne is any kind of wheat product. Wheat gluten is known to cause many health problems. Wheat gluten is kind of like glue that holds things together in many vegan products in the store.

    Many vegan foods that resemble meat actually contain lots of wheat gluten. Also a very popular food chain that brags about being vegan and vegetarian and the name has something to do with veggies and being grilled or something (I am being vague about using their exact name as I don't want to directly bash them), they use a lot of gluten.

    So while myself and others have in the past adopted a vegan diet to try and cure acne have had success on a vegan diet. It was however a very specific vegan diet.

    White sugar is vegan, also wheat gluten. MSG and its many names (you might want to research all of the names of MSG) is also vegan but is not good for you at all. So people throw the Vegan word around thinking that it is a magical characteristic of a diet that healthy.

    This is where many vegans that are unhealthy go wrong. They are eating tons of vegan foods that are clogging them and making them sick. Bread can be very constipating and it contains wheat. Most people have a food allergy to wheat even if they don't make the connection between the bread they eat and their symptoms.

    I am almost positive that if you are reading this right now you are probably very frustrated with all the conflicting information on the web. The big food corporations pay "ghost writers" to write nonsense to promote the foods they are selling even if they know what they are selling might not be good for you.

    To avoid becoming brainwashed by the media, and to avoid what they are selling, why don't you make yourself a challenge. I challenge you to prepare almost all of the food and know what each and every ingredient that goes into your body is and what it is made of.

    I challenge you to write down every last thing that goes into your body. It isn't as hard as it seems if you try to eat whole foods. Eat tons of Romaine lettuce, carrots, almonds and other raw nuts (no peanuts) extra virgin olive oil. sea ​​salt, raw hone, olives, and other fruits and vegetables for a few weeks.

    This means no fast food. You see French fries are vegan. In my opinion looking at the acne and food connection is that they are very unhealthy and probably cause me to break out in acne. The reason is that french fries are deep fried in oil and the oil is damaged by heat. Also the oil is probably made from GMO ingredients. This topic is too broad to explain why it is not good for you.

    In short your body might perceive the oil as an allergen. Also the fries are also probably covered with table salt. Table salt is not good for acne.

    Also there is a very popular fast food chain (which is probably the most well known for giving away free toys in the meals of the kids and brainwashes the youth and makes them sick at such a young age that they never know health and what it feels like their entire life) that clearly admits that their french fries contain things that can cause cancer. I am not kidding you. We need to read the warning on the fries.

    Anyway, I don't want to get sidetracked, To help you to cure your acne and to be truthful, I want to let you know that adopting a vegan diet to cure acne is a good idea to try. It's just that you need to be very selective in designing your vegan diet.

    Simply being labeled "Vegan" does not make it healthy.

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    Source by Teddy Grandy

    Views: 0

  • The Importance of Business Systems

    The Importance of Business Systems

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    “If you can’t describe what you are doing as a process, you don’t know what you’re doing” – W. Edwards Deming (1900-1993)

    What are business systems?

    Business systems are documented procedures setting out how your organisation operates. They are processes, usually combining actions taken by people and some form of automated application, organised in such a way so as to meet a given set of business objectives. Such systems can generally take place without the business founder / owner’s direct action, over and over again, as efficiently as possible.

    Examples of processes may include how your staff should answer the telephone, how they take and pass on messages; the procedure for raising, approving, placing and receiving orders; the process for generating, checking and sending out client invoices, as well as receiving payments and following up on outstanding bills etc.

    Regardless of the size or type of your business, it is likely that you already have set procedures in place covering many functions within your organisation, which employees follow out of habit or as directed by their supervisor / manager.

    Business systems are the manual for your business; the “know-how” of any business that many business founders / owners usually hold in their head, and have not got round to putting onto paper.

    Why implement business systems?

    There are many reasons and just as many benefits for having established and documented systems in your business, some of which include the following:

    1. They provide a framework for your operations and an effective structure to support your business.

    2. They improve consistency: production, delivery, customer service, after-sales care etc.

    3. They improve results and/or productivity, because you and your employees don’t have to re-invent the wheel every time.

    4. They provide a better work environment for your employees, as an effective system will contribute to clarifying roles and responsibilities as well as providing staff with some guidelines to refer to.

    5. They ensure compliance with legislation, safety regulations or any other legal requirement specific to your type of business operations.

    6. They give your business the ability to expand and they facilitate business growth, as they will make your business more attractive to any potential investor or buyer.

    What system works best?

    Although there are similarities across many functions, such as Accounts, Human Resources, Sales, Stores, Logistics etc., unfortunately there is no one perfect, one size fits all system that works for all companies. Any system will need to integrate the company’s business objectives, its people and the way it provides its products or services.

    It is important to have a well-designed system, customised to your type of operation, and thought out by people at all levels within the organisation.

    Such a system will be more likely to be followed by all employees, because they have been involved in its design, and they understand the value that having a system in place brings to the quality of their work and the service they provide to customers.

    One point to keep in mind is that having great people working with poorly designed systems – or no systems – is likely to lead to an under-performing business. On the other hand, great systems without good people won’t work either, hence the additional benefit of involving employees in designing a system, or simply in documenting the processes they are following.

    Equally so, employees who have been trained in your business systems should also feel empowered enough so that they don’t feel they just have to follow a given script without using their head.

    For this reason, it is important to encourage feedback not just from your customers, but also from your employees and to use such comments to review and to continuously improve and develop your business systems.

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    Source by Cecile Scaros

    Views: 0

  • How Does ENERGY HEALING Help You Feel Better, Relieve Pain, and Assist Humans and Animals to Heal?

    How Does ENERGY HEALING Help You Feel Better, Relieve Pain, and Assist Humans and Animals to Heal?

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    We all live in overlapping fields of energies. These fields includes your physical body, your auric field (which consists of 6 additional bodies), electromagnetic fields that emanate from your organs and other body parts, and the energies of everyone and everything around us, including the earth.

    Since everything is energy, including your consciousness, you might wonder how healing can ever happen without paying attention to the energy aspects of your bodies.

    What Is Energy Healing?

    Energy Healing is any healing method which helps restore and maintain the energy systems of your bodies by working directly with the energy of your bodies.

    The term “energy healing” is used today for what has also been called “hands-on healing”, “spiritual healing”, “psychic healing”, and even “energy medicine.”

    In energy healing, a wide variety of techniques can be used. Whatever techniques are used, they directly address the energetic levels of your bodies.

    While tools such as stones and crystals, acupuncture needles, pendulums, singing bowls, and others can be part of a healing session, many practitioners use only their hands and their intention to facilitate a healing.

    Clean, pure, love-filled energy (life force, prana, chi, ki) is made available to the bodies, while inappropriate energies are assisted to leave the bodies.

    To be healthy and in balance, your energy must be able to flow freely, smoothly, and harmoniously.

    What Can Disrupt the Energy of Your Bodies

    Infection, injury, toxins, stress, too much or too little of any substance are all examples of events than can disrupt your bodies’ energies.

    When you’re sick, it’s because the flow of energies has been disrupted, causing some areas to be jammed up with too much energy while others areas are depleted. The disruption can come from accidents, infections, emotional traumas, and many other stressful situations.

    Several things can happen during an energy healing session to restore the smooth flow of energies. Here are some common examples.

    • Disorganized and chaotic energy patterns become organized and harmonious.
    • Blocked energy flows are unblocked.
    • Sluggish energy flows are restored to normal speed.
    • Depleted energy areas are assisted to regain a normal, healthy level of energy.
    • Excesses of certain types of energy are reduced to normal.
    • Disconnections between the spirit and body parts are reconnected.
    • Communication breakdowns between body parts are restored.
    • Energy that doesn’t belong is helped to leave the body.
    • Repair the physical body’s etheric blueprint (template).
    • Repair, balance, and harmonize the chakras.

    Some examples of energies helped to leave are:

    • viruses, fungus, bacteria.
    • memory patterns of old injuries.
    • memory patterns of weapons from this or past lives.
    • emotions that haven’t been fully expressed.

    These are just a few examples of what energy healing can address.

    What Do Energy Healers Do?

    Energy Facilitators support the body’s natural healing abilities.

    Energy Healers facilitate the healing process, which is done by the bodies themselves. An Energy Healer is more accurately described as an Energy Facilitator. They do not actually heal the body. The body must heal itself.

    The body, when functioning optimally, knows how to heal itself and how to restore balance. It wants to be in balance and harmony and good health.

    What Are Some Benefits of Energy Healing?

    Here are some of the benefits you may experience:

    • Relief from physical/emotional pain and other symptoms.
    • Feeling increased relaxation and calm.
    • A reduction in your stress level.
    • Feeling empowered to take charge of your healing process.
    • A sense that your physical body is stronger or more able to cope with life’s challenges.
    • A sense of well-being, comfort, integration, and wholeness.
    • Feeling more at home in your body.
    • Feeling more energized and more playful.
    • Feeling more balanced and more grounded.
    • Improved appetite; greater control over unwanted habits.
    • Increased interest in life.
    • Increased immune system function.
    • Faster or more complete healing from illness, injuries, or surgery.
    • A feeling of greater alignment with your I Am Presence.
    • An opening to receive more Divine Love.
    • A sense of greater connections with the Divine or with your I Am Presence.
    • A feeling of greater alignment with your spiritual path.

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    Source by Nedda Wittels

    Views: 0

  • Discover How to Write Articles and Make Money Online Without a Website

    Discover How to Write Articles and Make Money Online Without a Website

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    Welcome to the world of stress free profits using the famous but very little understood and less used secret of article writing.

    Content writing is one of the cool ways to make money online without a website if you know the secrets. There are many ways you can make money online with this writing business. However, for you to make money online from the business, you must first understand that content writing is a business on its own and a lot of people make money online from it everyday.

    It is one of the freelance jobs available on the Internet where you can make money online as there is hungry market for the business. The internet is all about offering information to people. The hundreds of millions of websites and blogs you see all over have written content in form of articles, reviews, sales copies and profiles

    The objective of most websites and blog owners is to make money from their sites by selling products, services and pay for click programs. The good news for you as a good writer is that all the above mentioned money making means lies on article writing.

    Therefore, going by the number of articles involved, it is quite obvious that websites and blog owners cannot write these articles all alone due to lack of time. In fact, they never dare writing the articles themselves otherwise they may not have time to attend to other important issues. All they do is to outsource article writing job to freelance writers who do the writing for them for a fee. This is why writing has become a means of generating unending income online.

    Fortunately, you don’t even need to invest a dime in the business for you to make money online without a website. All you need to do is to spend few hours a day to help webmasters and blog owners write the articles they need to promote their sites.

    The volume of job to do is limitless and ongoing. This implies that there is always market for you if you are hardworking and dedicated. For instance, a client alone can keep you busy for several months. Depending on how fast you are in article writing, you can earn $2,500 monthly.

    The Approach

    1. You can be hired by people to write articles for them

    2. You can create free blog and add contents to the blog from time to time

    3. You can write articles for submission to various article directories for money.

    These are some of the ways you can make money as far as content writing business is concerned.

    However, you must be ready to follow the rules of the game and make a move to make money in this business. Consequently, do not just fold your arms, dream and relax but try to actualize your dream by working hard. Be fond of discovering opportunities in problems and do not be one of those who see problems in opportunities.

    You will be at the same spot you are for years if you fail to make a move. Hello! Wake up from your slumber now and start writing articles to make money online fast!

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    Source by Oluseyi Sogaolu

    Views: 0

  • Gender Wars: Has The Time Come For Men And Women To Heal Their Emotional Wounds?

    Gender Wars: Has The Time Come For Men And Women To Heal Their Emotional Wounds?

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    When it comes to the mainstream culture, it is not uncommon for men to be put down and to be seen as the bane of the earth. This doesn't mean that women are not also seen as the problem, but this could be seen as something that takes place underground, to speak.
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    So, while there are plenty of newspapers and TV stations that are only too happy to paint all men as being a certain way; there are also plenty of websites and videos online that are happy to paint all women as being a certain way. It could then be said that it is socially acceptable to put men down but the same can't be said when it comes to putting women down, which is why this has to be done in a more covert manner.

    Plenty of Fuel

    It seems that not a day goes by when there isn't something in the mainstream media that doesn't add to the view that men are worthless human beings. Sometimes, something small will be used to prove this, while at others, it will be something that is far bigger.

    For example, when a woman in the public eye claims that she has been harassed by a man, not a lot of thought is given as to whether or not this actually took place. There are at least two reasons for this: firstly, women are often portrayed as innocent and pure and, secondly, all men are often portrayed as primitive beings that can't control their urges.

    The Accepted Narrative

    Thus, regardless of whether or not a man is actually guilty, he is going to be used to support the view that all men are the same. Clearly, if a man is found to be guilty the appropriate action should be taken, but, without the evidence that he has done anything wrong, it shouldn't be assumed that he has done anything wrong.

    The people in the media who support this view of men don't seem to care about the damage that something like this could do to an innocent man's life. It's as though a man deserves to have his whole life ruined, irrespective of if he has done anything wrong.

    Validation

    And, if a woman believes that are men are the same, it is going to be music to her ears to hear the mainstream media talk about men in this way. A woman like this may have been in a number of abusive relationships, for instance.

    Seeing a man go from a position of power to being destroyed is then going to be extremely satisfying. She probably won't have met this man, but seeing him go down will allow her to indirectly experience revenge.

    The Other Side

    When it comes to what is taking place away from the mainstream media, there is plenty of content that basically goes into how worthless women are. One of the main themes is that women can't be trusted and that if they find another guy who has more money / status, they will soon disappear.

    And, if a man has been in a relationship where the woman walked away or if he has found it hard to experience fulfilment in this area of ​​his life, for instance, he can be only too happy to hear other men say that women are useless and good for one thing. It will be as though they are enslaved to their biology, are heartless, and are not consciousness beings, unlike men who are in control of their urges, have a heart, and are aware.

    Letting of Steam

    Due to what a man has been through he will no doubt carry a lot of anger, anger that is likely to allow him to avoid feeling powerless and helpless, for instance. The experiences what he reads about online will end up enforcing what he already believes.

    This is then likely to create even more distance between him and women and make it even harder for him to experience fulfilment in this area of ​​his life. Even so, what this will do is allow him to be right, and this is one of the ego minds greatest needs – being wrong is seen as something that will lead to death.

    A Messy Situation

    There are then women who hate all men and men who hate all women, along with men who hate themselves and pedestalize women and women who hate themselves and pedestalize men. Therefore, even though it is not possible to say that it is only men who are under attack, it is undoubtedly more socially acceptable to attack men.

    If someone believes that all men / women are the same and is happy to see a man / woman suffer, it is likely to show that they are carrying a number of emotional wounds. If they were able to get in touch what how they feel below their anger and rage, they may find that they feel rejected, powerless, helpless and worthless, amongst other things.

    A Reactive Existence

    Being in touch with these feelings is then likely to cause them to feel incredibly vulnerable; whereas being in touch with the more surface level emotions (such as anger and rage) is likely to allow them to feel strong and powerful. But, while living in this way can allow them to feel strong and powerful, it is going to cause them to be controlled by how they feel.

    Not only this, it will stop them from being able to realize that not all men / women are the same and to see them as individuals. What they believe will define how they experience life, thereby stopping them from being able to experience anything that goes against what they believe.

    A Deeper Look

    When it comes to the emotional wounds that someone can carry, what has happened in their adult life is certainly going to play a part. Yet, what is likely to play an even bigger part is what took place during their early years, and what has been passed down from their ancestors can also play a part.

    What took place during their early years that can be what is defining how they perceive men / women and the kind of men / women women they will be attracted to and attract. If someone had a father or mother who was abusive, for instance, it would have most likely caused them to experience a lot of trauma, and, it would have laid down the foundations for them to be drawn to men / women who would also abuse them.

    Two Levels

    How they were treated at this stage of their life would have become familiar, and what is familiar is what is classed as safe to the ego mind / unconscious mind. The years would then have passed but they are still going to carrying the trauma of being violated and abused.

    It is then not going to matter what their conscious mind wants to experience, as their unconscious mind will want to experience what took place all those years ago. The trouble is that if someone is not aware of how their early years are affecting their adult life, it will be normal for them to feel like a victim and to blame all men / women.

    Self-Victimization

    If going within and working through emotional wounds was easy, it would be a part of everyone's life One of the biggest challenges to doing this type of work is that the mind disconnects from the body to avoid pain, which can result in someone's inner wounds being projected onto others.

    The people who they come into contact with will then press their buttons, so to speak, but they won't be able to see that these people are mirroring back what they need to resolve within their own being. Without this understanding, they can end up seeing themselves as a victim and other people as perpetrators.

    Conclusion

    If someone wants to grow and develop and no longer wants to feed into this drama, they may need to reach out for external support. With the assistance of a therapist or a healer, for instance, they will be able to gradually work through their emotional wounds.

    But, if someone is caught up on their own stuff due to their current level of consciousness, there will be no reason for them to change. As a result of this, they will continue to live a reactive life and to play out their early drama.

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    Source by Oliver JR Cooper

    Views: 0

  • Dangerous Driving Habits

    Dangerous Driving Habits

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    Many of today’s drivers have dangerous driving habits. You do not have to travel far to see people driving with risky driving techniques. Dangerous driving habits can be observed on highways, on residential streets, and in parking lots. Dangerous driving habits are not only fraught with danger to the driver performing them, but to the public as well.

    Everyone eventually crosses paths with a reckless driver! Many of us survive these encounters, but some do not. Dangerous drivers kill people and destroy property everyday. As a result, Insurance companies cite dangerous drivers as one of the main reasons for the skyrocketing cost of automobile insurance.

    There are drivers from all age groups that have dangerous driving habits. Younger drivers can be dangerous drivers simply because they lack experience driving in various environments, such as driving at night, or driving on interstate highways. Older drivers are sometimes dangerous because their senses and reflexes are not as sharp as they once were.

    Technology has also added to dangerous driving habits. Cell phones are now more popular than ever, many drivers have cell phones. While driving in town or on the highway, it is rare not to see someone driving while talking on his or her cell phone. Another dangerous driving habit is applying makeup while driving. Applying make-up while driving is thought to be a leading cause of accidents, and is completely irresponsible. One of the most common dangerous driving habits is eating while driving. Many drivers leave the drive through lane of their favorite restaurant and immediately pull onto a road while trying to eat and drink the food they just purchased. All of those bad habits can distract a driver from paying attention to other drivers on the road and being aware of road conditions.

    There are many kinds of driving habits that are considered risky. Speeding is a very common driving habit that can lead to a disaster. Drivers that speed are engaging in reckless and impulsive behavior. It is especially dangerous to speed in residential neighborhoods where children and pets may be playing. Speeding drivers can also be dangerous in neighborhoods where homeowners in their vehicles are entering and exiting their driveways.

    Another category of dangerous driving habits is failing to use turn signals. Proper use of turn signals can help prevent most accidents. Failing to use turn signals properly can increase the rate of accidents with other vehicles and pedestrians. Turn signals are simple devices that can give advance notice to other drivers about your driving intentions. It is unfortunate that failing to use such a simple device can cause so many tragedies in terms of lives and property damage. Road rage is a one of the consequences of failing to use turn signals. Many drivers become enraged when they barely escape an accident due to another driver failing to use a turn signal to notify them before changing lanes or making a turn.

    Many dangerous driving habits are a result of over confidence. Drivers with years of experience sometimes become dangerous drivers because they are over confident with driving their particular vehicle, or a particular route between home and work. They are not prepared when something out of the ordinary occurs.

    There is an old saying, “Good habits are as hard to break as bad habits.” If you have dangerous driving habits you can change them by applying good driving skills for a few weeks, after a few weeks many of these good driving techniques will become your new habits. You should practice watching for speed limit signs, and adjust your speed if necessary. If you practice using turns signals every time you make a turn or change lanes it will quickly become a habit. Developing good, safe driving habits may one day save your life or the life of someone close to you.

    (c) 2006, Marcus Barber

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    Source by Marcus Barber

    Views: 0

  • Journey of a Drug: Design to Market Seller

    Journey of a Drug: Design to Market Seller

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    Where do the medicines we take from chemists come from? How do the doctors know which drug is good for which disease? How the medicines really are able to cure a particular ailment they have been prescribed for? Do these questions come to your mind, whenever you buy any medicine?

    Come, let us today know about the medicine development from the beginning …

    The development of medicine is called a Clinical Research and has different Phases. Phases of the clinical research are the steps of experiments with a health intervention in an attempt to find enough evidence for a process which the scientists think would be helpful in medical treatment.

    The pharmaceutical study starts its journey from a drug design and drug molecule discovery which further progresses into animal testing and then human studies to see the drug's effectiveness.

    Drug undergoes many trials- Preclinical, Phase 0, Phase I, II, III and IV. Sometimes combined trials also are undertaken to reduce the time of development, like Phase I / II and II / III.

    Pre-Clinical Study

    When the drug molecule is identified, it undergoes many in vitro ( test tube or cell culture ) and in vivo ( animal ) experiments. These experiments are conducted to know the preliminary efficacy, toxicity, and pharmacokinetics of the various doses of the drug. Many drug molecules are designed at a time and these pre-clinical studies let the pharmaceutical companies decide which molecule has a greater potential in further studies.

    Design of the Studies:

    Trials are always conducted by following the set of steps, called the protocol, developed by the researchers to find the specific questions related to the medical product. Information from the prior studies become the base for the researchers to develop research questionnaire and objectives:

    • Participant selection
    • Number of participants
    • Duration of the study
    • Controlled or not
    • How and what dosage will be given
    • What and when the data will be collected
    • Review and analysis time

    Phase 0 Study

    It is also called micro-dosing trials, 10-15 human subjects are taken and single sub-therapeutic doses are administered to gather the pharmacokinetic ( PK ) data of the drug. This enables the company in deciding to go or no go for the further development of the drug, based on more relevant human data instead of animal data.

    Such trials exceed the speed of promising drug development by establishing whether or not the drug acts on humans as expected in pre-clinical studies.

    After the company decides to take the molecule of the drug forward in development, it will have to submit the data of its preliminary studies to the FDA called Investigational New Drug ( IND ) application filing.

    Phase I Study

    Also called First-in-man studies as these are the first stage of human testing studies. These are the studies which are designed to determine the maximum dose that can be administered without showing adverse effects.

    Contract Research Organizations ( CROs ) conduct such studies in the clinical trial clinics where medical staff provides full-time attention to 2-100 healthy subjects enrolled for the study and collects the data.

    These studies determine the safety ( pharmacovigilance ), tolerability, pharmacokinetics ( PK ) and pharmacodynamics ( PD ) of the drug. The design of Phase I studies is dose-ranging also called dose escalation studies conducted in controlled clinics called Central Pharmacological Units ( CPUs ).

    Usually, healthy subjects are hired but sometimes terminally ill patients like of cancer and HIV and also those who have already tried and failed to improve on existing medications.

    There are two divisions for Phase I study:

    Phase Ia: Single ascending dose

    Phase Ib: Multiple ascending dose

    Phase II Study

    More than 100 diseased subjects are enrolled for a longer period study, to know the benefits of the drug along with its safety which includes genetic testing. These studies are also called as "Proof of Concept or Pilot" studies.

    This is the phase when the drug's development can fail due to toxicity or less than expected results.

    Two divisions of this phase are:

    Phase IIa: Pilot study, to determine the clinical efficacy or the biological activity.

    Phase IIb: Dose-finding study, to check the biological activity with minimal side-effects.

    A combined trial determining the efficacy as well as toxicity are Phase I / II trials.

    Phase III Study

    These are pre-registration trials means the data of this study is submitted to the regulatory agency through New Drug Application (NDA) for its registration. Also called Pre-marketing or Pivotal trials.

    Such studies are multicentral, randomized, in large diseased population ( more than 500 ) with much longer duration of treatment and short follow up period, to determine the long-term safety and efficacy of the drug.

    Even if the regulatory submission is pending, the drug is received by the patients in case it's a lifesaving drug until the drug can be purchased.

    'Label expansion' that is drug can treat an additional disease, other than the disease for which the drug is already approved, may also be the reason for running the Phase III trial.

    It is said that for FDA ( United States Food and Drug Administration ) and MHRA ( United Kingdom's Medicines and Health products Regulatory Agency ) needs at least two trials of successful trials data to register the drug.

    After these trials, the drug is approved for market selling.

    Phase IV Study

    These are Post Market Safety Monitoring studies done after the drug is registered. Also called Late Phase or Confirmatory trials.

    This kind of study determines the long-term adverse effects on the much larger population for a very long duration (at least 2 years). If harmful effects are detected in this study, then the drug is disapproved and the company has to retrieve the drug from the market as it can no longer be sold.

    The entire journey of the drug from a molecule to a market selling product takes around 15-20 years.

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    Source by Nidhi Sharma

    Views: 0

  • Dating: Is It A Bad Idea To Have Sex On The First Date?

    Dating: Is It A Bad Idea To Have Sex On The First Date?

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    Many, many years ago, sex was something that people would typically have if they wanted children. Nowadays, it is something that lot of people have if they want to experience pleasure.

    In the past, then, it was generally seen as having one purpose and in the present, it is generally seen as having another. Now, while there were people in the past who did have sex for other reasons, there is no denying how different it is today.

    Separated

    If it wasn’t for the contraceptive pill, it is highly unlikely that sex would be seen in the same way as it is often seen today. Naturally, this has lowered the risk of a woman getting pregnant, thereby making it possible for her to have sex without needing to worry about what will happen after.

    Along with this, a man can use a condom to stop his sperm from causing any problems. So, in the same way that someone might have a piece of chocolate to experience pleasure, they can also have sex to achieve the same outcome.

    It’s Just Sex

    Unlike most of their ancestors, this could be the only thing they know. Therefore, if they were to hear about how, in the past, people typically had sex to procreate, they may find it amusing.

    In their eyes, sex could be seen as something that is there to be enjoyed; only having it to create a child is not going make any sense. And, as sex is something that can be extremely enjoyable, why would anyone only want to have it in order to procreate?

    An Easy Decision

    If someone has this view when it comes to sex, they may have no trouble sleeping with another person on the first date. This could be seen as a way for them to find out if they are sexually compatible.

    Sex will be such an important part of their life that they won’t want to be with someone who doesn’t do it for them in the bedroom. In addition to this, they could believe that this will allow them to get to know them better.

    Nothing to Lose

    The alternative would be for them to wait a little while, only to find out that they are not sexually compatible. After having been with them for a while, it could be a lot harder for them to move on.

    One would then have wasted a fair amount of time, time that they would have saved if they got down to business straight away. It would have also taken them a lot longer to find out about things that they might have found out about in a night.

    The Only Option

    Taking this into account, someone would be old fashioned or even a prude if they chose to behave differently. It would be in their best interest to ‘liberate’ themselves and to just go for it on the first date.

    This might go against what they currently stand for, but they will soon realise that it is the right thing to do. When this happens, one will no longer be allowing an outdated inner model to run this area of their life.

    Back To Reality

    However, although this might seem like the best approach to take, it doesn’t mean that this is the case. One of the big problems with having sex more or less straight away is that it can cloud one’s judgment.

    If human beings didn’t have an emotional self and only had a mental and the physical self, it wouldn’t matter. Their emotions wouldn’t be there to effect their judgment, allowing them to think clearly afterwards.

    Numb

    If someone can have sex straight away and not be affected by it, it could simply show that they are emotionally shut down. Having sex with someone straight away is not going to affect them, but as if they are out of touch with their emotions, it is unlikely that they would be able to have a real relationship anyway.

    This could then explain why someone like this would put such a big emphasis on sex; the other part of their being, their heart, is not going to be open. A lot of their energy will be stuck in their genitals as it won’t be able to reach their chest area.

    Many Elements

    Sex is undoubtedly an important part of a relationship, yet there are a number of other things that are just as important. It will be vital for one to find out if they actually have anything in common with someone and to find out if their values match up.

    As there are many parts to their own being, they will need to be with someone who has a being that matches up with these parts. This will be what allows the relationship to last once the early sparks have settled down.

    The Easy Option

    Getting naked and having sex with someone may seem like a great way get to know who they really are, but this may be a time when they are still hiding their true self. Ultimately, it is one thing for someone to reveal their body; it is another thing altogether for them to reveal who they actually are.

    If one thinks that getting naked with someone means that they are getting intimate with them, this is not going to cross their mind. What will also make it harder for them to realise this is if they have come to equate sex with love.

    Awareness

    This is then not about whether or not having sex on a first date is ‘good’ or ‘bad’, it is about looking at the consequences of behaving in this way. Having sex on a first date could lead to a fulfilling relationship; then again, it could cause one to end up with someone who is not right for them.

    Their emotions and hormones will be all over the place, making it just about impossible for them have a balanced outlook. Their thinking will be off and their view of the other person will also be off.

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    Source by Oliver JR Cooper

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  • 5 Steps to Move From Employee to Entrepreneur

    5 Steps to Move From Employee to Entrepreneur

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    Have you been considering quitting your day job in favor of starting a business? Have you just lost your job and are currently exploring alternative ways of earning a living? Have you always dreamt of owning your own business some day?

    Before you take the leap of faith into self-employment, consider these 5 steps:

    1. Get clear on your goals/passions – It’s not enough to decide to become a business owner. There are several questions and things to consider before you move forward in becoming a business owner. You will need to think about what kind of business you wish to run. You`ll need to determine if you wish to grow it from scratch, buy an existing business or purchase an available franchise. But even before you decide that- you should think about how the business will fit in with the rest of your life. Running a business can be a huge commitment of time and money. So ask yourself what do you enjoy doing or what will bring you joy? You will spend much of your day on your business so it’s a good idea for the business to provide work you actually enjoy doing. Ask yourself what you are most passionate about? What would you love to do? What is your dream job/business?
    2. Do your research/homework – Don’t make any rash or impulsive decisions and don’t leave your day job until you are absolutely sure of what you want to do and have a plan for doing it. Take the time to do good research by researching the industry, the marketplace, your potential target clients, your competitors. Do proper business research including a SWOT (Strengths, Weaknesses, Opportunities, Threats) analysis. Get a good handle on projected revenues and realistic operating costs as well as an understanding on how long it will take to breakeven and generate more revenues than expenses. Identify your personal strengths and skills and determine if there are any skills gaps. Determine how you will close any skill gaps or lack of expertise. Which gaps can be closed through skills training? Which gaps can be closed through recruiting the right people? Which gaps can be closed through coaching or mentoring? Determine what options and opportunities are available to you right now?
    3. Learn from others’ mistakes – There is no shortage of people who have started or run a business. Speak to as many people as you can who have gone before you. Learn what you can about what works, what doesn’t, and what mistakes others have made. Don’t waste valuable time and money. Be open to hearing others` perspectives on what they would have done differently. Hindsight is always 20/20.
    4. Business Plan ahead – Do the work and develop a business plan. While it may be a lot of work, it will be time well spent and most financial institutions will require one if you are searching for financing. The process of business planning is not only to prove to the bank that your business will be a success, it’s also a roadmap for you to follow to ensure success. Running your business finances can be like running your weekly, monthly or yearly personal budget – so if you haven’t developed good budgeting and financial management skills, it might be particularly challenging and doubly important to have a solid business plan.
    5. Hire a mentor – Starting and running a business can be challenging or even lonely at times. In addition to the day to day operations of the business, you may be mentally or emotionally overwhelmed by being a business owner. Having a safe place to go to for advice, guidance, and accountability or simply as a sounding board can be just what you need to help you make the transition into entrepreurship easier and smoother. Good coaching and mentoring can really help you fast track your transition.

    While there are many advantages to being an entrepreneur, it`s important for you to also consider the downside of self-employment. Become a business owner armed with as much information, skills and tools you can to ensure a successful transition from employee to entrepreneur.

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    Source by Linda Cattelan

    Views: 0