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  • Breast Cancer The Cure

    Breast Cancer The Cure

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    You have my permission to publish this article electronically or in print, free of charge, as long as the bylines are included. A courtesy copy of your publication would be appreciated.

    Breast Cancer The Cure

    There is no known cure for breast cancer. More than 1.5 million people will be diagnosed with breast cancer this year worldwide. Scientists don’t know why most women get breast cancer, yet breast cancer is the most frequent tumor found in women the world over. A woman who dies of breast cancer is robbed of an average of nearly 20 years of her life. Breast cancer knows no social boundaries. It’s a disease that can affect anyone. Some prominent women who’s lives that have been touched by breast cancer include Jill Eikenberry actress age 52; Peggy Fleming age 49 figure skater; Kate Jackson age 50 (Charlies Angels); Olivia Newton-John age 50 actress singer; Nancy Reagan age 77 former first lady; Melissa Etheridge age 43 singer; and the beautiful Suzanne Summers actress. These high rates of breast cancer are not acceptable to the women of the world and must be met with scientific research that provides results.

    Despite over a decade of research, and more than $1.7 billion spent, hundereds of women worldwide are dying from breast cancer every day. Yet doctors don’t know how breast cancer starts or how to cure it. Doctors are still approaching treatment for breast cancer in the same old fashioned ways: surgery, radiation, and chemotherapy. Barbarick treatments…And scientists keep doing the same old redundant research that’s simply not working. It doesn’t have to be that way. Gen Cells Cures is a scientific biotechnology company that is focused on a cure for breast cancer. The company is dedicated to curing breast cancer before it’s too late for you. We’re not interested in a cure in five, ten, or twenty years from now. We want your cure for breast cancer within a year or two. We don’t want you to have to under go surgery, radiation, chemotherapy or take toxic drugs.

    Why Gen Cells Cures? You can search the medical journals; you can search the internet until your blue in the face. You will find the same old news which is no new news about breast cancer research and treatments. Breast cancer research is locked up in a black whole. Gen Cells Cures is approaching the cure for breast cancer from different angles and using tomorrow’s scientific technologies today. Our expertise is in stem cell research and genomics. Malfunctioning stem cells have already been linked to the development of breast cancer. We’re not talking about using generic stem cells from an egg and sperm cell. There is no genetic match for you with the politically controversial generic stem cells that are always in the news. The isolation of cancer stem cells, coupled with our understanding of genetic mutations causing cancer, and our knowledge of genomics will result in ways to eliminate cancer cells while sparing normal breast tissues.

    Genetics and Breast Cancer

    People will tell you to accept what you can’t change…Your genetics, your genes, the genes your mother and father handed you when you were born that came with their particular genetic make-up. Most inherited cases of breast cancer have been associated with two genes: BRCA1 and BRCA2. The past five years has been a period of unparalleled discovery in the field of genetics, genomics, and stem cell research, but these discoveries are not being applied to breast cancer treatments. A job that Gen Cells Cures definitely wants to get our hands dirty in. Recently researchers have found that by blocking a gene called beta1-integrin the growth of tumor cells can be stopped. When this gene was removed the tumor cells quit growing. You don’t have to accept the genes that you were given at birth. Gen Cells Cures will be able to manipulate your genes to cure your breast cancer.

    Our Cancer Stem Cell and Genomics Program will bring together the top scientific minds in the world under one tin roof to maximize the use of diverse approaches to the understanding of cancer genomics fused with stem cell solutions. Gen Cells Cures isn’t looking for a multi-million dollar biomedical research center like the Stowers Institute in Kansas City, which is a medical center to be admired. A rented tin shack will do just fine. Of course, we would accept hand-me down michroscopes from the Stoweres (billionaires who bought their own multi-million dollar biomedical research center) if they would be gracious enough to grant them to us or we would accept a small prime the pump check to move forward with our research. The Stowerses and all the scientists from the Stowers Institute have an open invitation to visit our lab in the Caribbean. What we are looking for is a cure for breast cancer to stop the humiliation, pain and suffering this menace to society causes millions of women and thousands of men worldwide, and not a new biomedical center… Every dollar invested with us goes into pure medical research and equipment. The same offer goes out to all the millionaires and especially the billionaires of the world. People that come to mind are: Paul Allen, Bill and Melinda Gates, Jon Huntsman, William and Alice Goodman, Ann Lurie, Jamie and Karen Moyer, Harold C. Simmons, Alfred Mann, Sumner M. Redstone, Michael Milton and the Palm beach billionaires, there are simply too many to mention. The combined wealth of the three Microsoft billionaires alone is more than ten times the amount spent by the U.S. Federal Government on research to fight cancer and other deadly diseases. We know we’re in the wrong business to become billionaires ourselves. This kind of biotechnology has never produced even one billionaire. It’s the cure for breast cancer that we want.

    Simply put the cancer research organizations are funding the wrong researchers. It’s time to go outside the normal research channels. Do something different. The same story year after year after year and no cure. These unmotivated researchers just aren’t getting results. Let someone else have a shot at it. It’s time to try something new and different. A different approach. There are races for the cure, golf tournaments for the cure, there are walks for the cure, there are foundations for the cure. These foundations have been funding the same ineffective research for more than twenty years now. These foundations have been betting on the wrong horse. Joining the crusade won’t help if the research being done doesn’t take on a twenty-first century scientific approach. It’s been time to move forward scientifically for five years now. But today’s breast cancer researchers are stuck in a twentieth century mind-set. The Excuse is someday we’ll find the cure, but someday doesn’t help today’s victims of breast cancer. We need top notch scientific action today.

    The genetics are out of the bottle and stem cell research is moving forward whether the U.S. government likes it or not. Gen Cells Cures has moved off-shore to the Caribbean to avoid the political controversy over stem cell research. I am sure you won’t mind a walk on the beach with me to talk about your cure for your breast cancer. Once we have the cure we can take the cure from the bench to the patient without a long and costly wait for FDA approval. There are many advantages to not having big brother breathing down your neck. The governments of the United States and Western countries have nothing to offer except road blocks, red tape and detours. Our patients don’t have time for political smoke and mirrors. With a little luck we could have your cure before the time comes that you need that dreaded surgery and chemo.

    Our gifted world-class researchers are visionary and have been schooled in winning and have courage, creativity, can-do attitudes, burning desires, unfaltering belief and an obsession that they will be there first. By first we mean years ahead of the other biotechnology companies. Like determined, fighting NASCAR drivers our scientists are living to take the chequered flag of biotech and win the coveted race for the cure for breast cancer.

    Focused on breakthrough discoveries, Gen Cells Cures nurtures a culture that encourages high standards of excellence, original thinking, hard work and a willingness to take risks. Our world-renowned scientists believe in themselves and its belief that gets us there. The company will seek to develop a work environment that is results focused and team-orientated. We compete against time. Though we compete intensely we maintain high ethical standards and trust and respect for each other. Quality is the cornerstone of all our activities. We seek the highest quality information, decisions and people. Our success depends on superior scientific innovation. We see the scientific method as a multi-step process which includes designing the right experiment, collecting and analyzing data and rational decision making. It is not subjective or emotional but rather a logical, open and rational process.

    Our success comes from one simple fact; we are committed to being a science-based, patient-driven company, driven by that one special breast cancer patient…you.

    Gen Cells Cures lost most of our one million dollar start-up money in offshore bank scandal and currency devaluation last year. We are now actively pursuing financial support. Unfortunately, the Gen Cells Cures team is made up of great scientific minds and not great marketers, salesmen, or fund raisers. Yes, we are looking for a millionaire or billionaire without a cause to support our work, but if you are not our wealthy saviour, we welcome any help, be it financial or a donation of your time. The scientific team is on stand-by. What we’re lacking is the funding to go forward. We could use motivated salesmen to sell our research, fund raisers, skilled internet marketers or someone just to pass out flyers or mail out promotional material. We could use help from the media with publicity stories, ads and promotions to get the word out. We are particularly interested in looking for assistance from the billionaires of the world; there are approximately 600 in the world. Billionaires like Sergey Brin and Larry Page (Google billionaires), Rupert Murdoch, Ted Turner, and Oprah Winfrey and others who control the media could get our life-saving message to the world fast. We are also hoping that some of my celebrities friends will come forward and spread their wings to help support our breast cancer research: Steven Seagal, Charlie Sheen, Wesley Snipes, Danny Glover, Erik Estrada, Tom Arnold, Dolph Lundgren, Roger Clinton, Bill Clinton, Usher, Hulk Hogan, Ivana Trump, John Secada, Sylvester Stalone, Arnold Schwarzenegger, Mike Reno, Richard Branson, Cindy Crawford, Cher, Demi Moore, Michelle Pfeiffer, and other stars that I have had the good fortune of meeting in person and others celebrities that I hope to meet in the future. (Photos of Gerald and the stars can be viewed at his promotional group listed below.) I am waiting to get my photo with Suzanne Summers!

    Gen Cells Cure offers more than hope. We can do the job. If you’re going to eradicate cancer you have to have the right people doing the right research. One thing is for sure. We couldn’t do any worse than what the scientists before us have done. Which is virtually nothing! Help us alleviate the pain and suffering. Together, with your help, we can cure breast cancer.

    Article by Gerald Armstrong- scientist0707@yahoo.com

    Gerald is the owner of Gen Cells Cures

    Visit his group for information about “The Cure” for incurable diseases and aging.

    Group address [http://www.msnusers.com/cures]

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    Source by Gerald Armstrong

    Views: 1

  • The Real Reason Why Small Businesses Can’t Get Approved for a Loan

    The Real Reason Why Small Businesses Can’t Get Approved for a Loan

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    Oh no, not again. Yes, that’s right, I’m not going to go there… at least not for today. There’s no shortage of excuses and reasons why small businesses can’t get approved for business loans. It never fails to amaze me the coverage this topic gets especially when the national economy goes into recession or when major political races are at stake. Yes, I agree that small business growth and success is the economic back bone of the US and also, that more than 60% of the US workforce are employed by small businesses. But where I get off the group think is when it comes to the lack of financing for a small business with a business loan. In this article, let’s explore the REAL REASON that small business don’t qualify for loans and the truth may even surprise you.

    It’s Deeper Than Statistics

    I love numbers and even better, I love reading financial statements and the notes. The love for numbers did not become a passion for me in the world of small business lending until I came to understand that the financial statements tell the story of a business. Similar to the story behind the financial statements, there’s a story behind the statistics stating that small business owners can’t get approved for loans especially if they’re of a certain ethnic group, gender, and / or industry. I’m not completely washing away the reality that there’s a shred of discrimination in our world… hey, we live in a broken society with broken people. However, a large part of this thinking (small business owners can’t get a loan because of skin color, gender, etc) is just simply untrue. I’ve been on both sides of the fence so to speak in the world of small business lending. I’ve worked for a big bank, and I’ve worked for a not for profit community development financial institution and it’s always the same. The number one reason why small business can’t (and don’t) get approved for loans is due to the considerably large operating risk that exists in these businesses.

    Operating Risk: It All Starts with You

    What does operating risk mean? Well, here’s a question to bring some clarity. What speaks more to sustainability: a business that’s been operating for at least one year or a business that’s still in the owner(s) mind? I’d go with the first option. Operating risk means that you have and continue to execute on your business plan(s) and that the business is cash flow positive (i.e. returning a sustainable profit margin to cover costs and make you money). Here’s the sad truth: not many small businesses get to this point. Most if any, within two years are still trying to figure things out. OK, granted, there are levels to this particularly when you observe the diversity of businesses. However, I’m speaking to the ones that endeavor to obtain a business loan.

    In closing, I offer a couple of ways to minimize your operating risk and increase your chances of getting approved for a loan. (1) Grow tough skin and learn to survive. The game of business is one of survival. Most days, things will not go your way and you just have to stay the course, be adaptable, and stay true to the business mission. (2) Never forget the 3 P’s – Production, Processes, and Personnel. Become efficient in the production of what you offer for sale, create and put in place processes to enhance production efficiency and ultimately the customer experience, and finally, hire, train, and invest in people who share your vision for the business.

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    Source by Pierre Pinkerton

    Views: 1

  • Can I Heal Myself?

    Can I Heal Myself?

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    At the heart of most energy healing modalities is the concept of healing ourselves. Is this what we were built to do, but what our encoding or life experiences would have us forget? Why is it that we can embrace the idea of going to another source for healing; be it with the use of pharmaceuticals or seeing a healthcare provider like a Medical Doctor, Chiropractor, or someone in alternative medicine such as an energy healers, massage therapist, herbalist, nutritionist and so on, yet grasping the idea that the ability to heal has always been within, seems to be a hard concept for our human logical mind to embrace.

    We have all been taught (trained) to call the doctor, our mother, our pastor, our therapist or our rabbi when we are sick in mind, body or spirit. But we seem to forget to call on our inner knowing or what I call our inner healer.

    Recently I had a very bad virus, the kind that lingers for days. While I was awake one night in a full blown war with my body, I began to think about self-healing. What came to me in my feverish/delusional state was that I have been looking at this whole self-healing thing from the wrong perspective. Kind of like from the outside in, instead of the inside out. My thoughts were; if our goal on earth is to remember who we truly are and to experience the lessons that go along with that remembering, what some refer to as an AWAKENING, then the path to do so reside outside of our human body. Enlightenment is the transcendence of our human bodies and the remembrance of our true nature which is light and love. So why is self-healing so important? The question becomes can we embrace the idea that we have everything within our being, not our body to heal and transcend.

    When we say look within, go within or refer to your inner knowing it is not a physical reference. It is a reflection within our knowing of our inherent perfection and magnificence. “Heal Others, Heal Yourself” is the opening of the portal that allows us to see that our body’s inflictions, our negative emotions and our so called disconnection from Source is not the way the truth and the light. When we accept that our physical bodies and our emotional bodies are merely an illusion of this world, something to look past, to transcend from, we begin to see that the healing begins with our connection to Source and our inherent Divinity. When we connect and discover this we begin to transcend the need for our physical bodies to be whole and perfect. Whole and perfect is who we are without the density of our physical and emotional body. This body is only a vehicle to navigate this dimension, to teach the lessons it has for us in this embodiment. “Heal Yourself” is remembering that we are not our body.

    These statements can sometimes lead to a misunderstanding. As if I was telling you to not see a physician, a medium, a pastor, a therapist, etc. for support. This is not at all what I am trying to convey. The lesson here is for us to begin to listen to our inner knowing. I believe that the Reconnective Healing Frequencies connects us to a place where we can allow ourselves to be lead to what is needed. To look within first and ask what is needed. (our inner knowing always knows) Try not to look outside ourselves by asking others what we need. When we know with inner conviction that we need to speak to our physician, medium, pastor, therapist, healer and then we follow that knowing, we now are fully engaged in the process. It is our knowing that will lead us there, now we will have ears and hearts to actually listen to what and how these supporters are guiding us to heal ourselves.

    In Reconnective Healing some will experience a spontaneous physical healing, but ALL will experience a return to balance, by remembering or reconnecting to the “IT” factor which we will name Energy, Light and Information from the Source of pure love.

    I just wrote a lot of fancy words, but most of all what I want you to know, what I want you to hear is attached below! Print this, cut it out, laminate it and put it in your back pocket, just in case life will have you forget who you truly are:

    Who Am I

    The Healer Within

    1. You are made of light… nothing more nothing less
    1. Within that light is energy and information. This energy light and information is who you are in your infinite connection to pure love.
    1. You are not your physical body or emotional body. They are just an illusion of this time and space. The body is something to look past or transcend from, using the lessons the body may bring.
    1. Enlightenment is the transcendence of our human bodies and the remembrance of our true nature which is light and love.
    1. You are love, not made of love, not experiencing love, not sharing love, not looking for love, YOU ARE LOVE.
    1. You are the voice within, the knowing which has no beginning, no end.
    1. You are a divine being, connected to your Source, the IT factor or what I call God.
    1. God is omnipotent, omniscient, omnipresent, and omnibenevolent.
    1. The vastness of this Universe and Universes beyond cannot begin to corral the essence which you share with your Source. You are an infinite being connected to all.
    1. ‘Heal Yourself” is remembering that we are not our body. Healing yourself or self-healing is the allowance of your inner knowing to embrace and embody your divine and intrinsic perfection and magnificence.

    The frequencies of Reconnective Healing and Personal Reconnections reconnect you to the remembrance or knowing of these facts or as Ms. Jillian Fleer, Head of Insight and Development at The Reconnection says, the “Veracity” of who you are.

    Are you ready to embrace the VERACITY of who you are? Read Dr. Eric Pearl’s book “The Reconnection, Heal Others, Heal Yourself”, go online and visit The Reconnection web-site or you may want to call me or message me to further this conversation.

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    Source by Virginia Adams

    Views: 1

  • How To Tell If Someone Is An Entrepreneur

    How To Tell If Someone Is An Entrepreneur

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    One thing defines an entrepreneur – constructive action.

    Typically, they’re the salesman – doing *everything* to get people to buy their stuff. We all have the image in our heads; the “wheeler-dealer”, picking any opportunity to try and exploit (and other people) for profit.

    Indeed, the term “entrepreneur” seems to have drifted around the present lexicon – from “something you did” (typically to improve people’s lives) into a blend of “money mad hustler” and “someone who doesn’t ‘follow the rules’”.

    The reality is the modern meaning could not be further from the truth.

    Entrepreneurship isn’t a vocation or job. It’s not a label which you apply to yourself in order to make yourself more endearing to a particular party, or clientele… it’s a way of doing things.

    Many “entrepreneurial” types actually have jobs. They’ll never admit they are “entrepreneurs”, although they exhibit all the traits of one. The question is what these traits are, and whether you – or someone you know – has them.

    What Is An “Entrepeneur”?

    Entrepreneur is a word derived from French – loosely describing a “problem solver”.

    Whilst its connotation has changed over the years, the premise persists – an “entrepreneur” is someone who creates a “widget” and has the ability to encourage other people to buy it.

    What this “widget” is can be a commercial product, service or idea.

    It’s actually interesting… some of the greatest “entrepreneurs” of history actually had nothing to do with money. They were completely focused on the development of a particular “result” and committed themselves whole-heartedly to its realization.

    Whether this meant conquering the Persian empire (Alexander), developing the light bulb (Edison) or creating stable PC systems (Gary Kildall), conquering the Aztec empire (Cortez), the term “entrepreneur” really denotes someone who wants to build something.

    The BIG difference between “original” entrepreneurs and the swathes of new-age idiots (who typically aggrandize a hedonistic lifestyle + seem to have an infatuation for “crypto”) is that the former were typically committed to a single profession, and manage to “leverage” that through the development of increasingly ambitious “projects”.

    These projects could be anything… but they all had a core “reason” to exist. This reason was what drove the originator to pursue the endeavour, and continue even when it was questionable whether it was even “possible” or not. Obviously, the reason we remember them is that they not only discovered it was “possible”, but entirely feasible… hence their success.

    How To Tell If Someone Is One

    The typical sign is they will do strange things…

    • interest in esoteric ideas
    • pursuit of interests not directly correlated to the accumulation of wealth
    • strong displays of passion for particular subjects
    • immersive nature with different ideas (trying to recreate historical events etc)

    The point is that REAL entrepreneurs are not typically concerned about money at all.

    Their primary concern is the creation of a “thing”. What that thing is, is determined by either their character or interests… but in every instance of someone who’s achieved a large amount of success, they were completely and utterly focused on doing “their” thing no matter what.

    This is actually important.

    The modern world seems to have every 18 year old male wanting to be an “entrepreneur” – like it’s a badge of honour or something. If you’re not “growing”, you’re “dying”… right?

    The truth is that our society has become so focused on convenience that the majority of these money-grabbing idiots have absolutely no business even considering themselves “entrepreneurs”.

    They have no experience, no skills and are only latching onto the latest “fad” in order to escape the mediocrity which has come to pervade the West’s consumerist culture.

    Entrepreneurship typically follows YEARS of interest in a particular subject. It typically follows HUGE investments of time & energy into the cultivation of a skill set, experience and “involvement” in a particular space.

    Most importantly – entrepreneurship is about doing something “your way”.

    Stay Clear Of Modern Idiots

    The BIGGEST problem I continually see from the hoards of idiots is they are ALL following a “book” or some other “rules” on “how” to be an entrepreneur.

    I see it all the time… guys reading all the biographies, neural studies, latest books from the big wealthy fat cat – all trying to discover the “secret” to massive success.

    What’s ironic is that all of this stuff just works on the “outside” of the issue – the same people who read all the “stuff” end up with the SAME questions… “what do I sell?”- “how do I know if I’m going to make money on a product?” – “what’s the secret to getting rich?”.

    • If you have to ask “what do I sell”, you’re not an entrepreneur.
    • If you have to listen to what a “successful” person has to say on a subject, you’re not an entrepreneur.
    • If you have to consider all the “rules” put forward by others, you’re not an entrepreneur.

    The point is that the modern world is chock-full of wannabe losers. Even the “successful” ones aren’t actually truly successful – they may have made a bunch of money, but what did they actually achieve? The answer is relatively little (or even nothing).

    The truth is that if you want to “be” an entrepreneur, you have to get to work.

    EVERYBODY has their own work. Some are models. Some are footballers. Some are computer programmers. Some are painters.

    The “trick” is to do ANYTHING in order to get moving forward in an industry; clean the floors if necessary.

    Once you start to gain some progress, the “entrepreneurial” stuff comes from leveraging any progress made within it – either to create & market a product, or to help a market better appreciate the potential of another device/product.

    Traits Of “Real” Entrepreneurs

    • Quiet (or at least reserved)
    • Fully capable of embracing failure (indeed, using it as a spur to change/adapt)
    • Working constantly on different elements within their “industry” (again, everyone has a place)
    • Unafraid of social constructs (just because someone said it doesn’t make it true)
    • Laser focused on what “they” want to do (you want to bring sustainable farming to Africa? This is the type of thing a “real” entrepreneur will actually do)
    • Unafraid to give freely (most “entrepreneur” types are not attached to money at all… typically not having much until they find mercantile success)

    If you haven’t worked it out, the core is purpose.

    The modern world has very little emphasis on purpose; rather it focuses on productivity.

    Nothing wrong with this, but it devoids most people of their passion. It’s good for GDP and McDonald’s – but bad for the creativity lying latent within a large number of people.

    If you want to adopt “entrepreneurial” traits, the key is to become attuned to a particular “purpose” – through which you’re able to invest your entire life.

    If you’re just looking at Ferrari’s and thinking that you “kind of want to become rich” – entrepreneurship is not going to do that. It’s a very difficult road, with only the most persistent and enduring surviving.

    You need to get to work, and only then will you discover hidden opportunities into which you’re able to apply your expertise, experience or network to build something of real value to the world. This real value is then absorbed by the market, who’ll either pay handsomly for it – or reject it. This is pretty-much what determines whether someone could be considered an “entrepreneur” or not.

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    Source by Richard Peck

    Views: 0

  • 3 Ways Web Design Works to Help Your Business Grow

    3 Ways Web Design Works to Help Your Business Grow

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    As you know, web design and development affects your business and audience. It is the first thing they see concerning your business, so it ought to make a good impression. Below are three important aspects of web design:

    1. Makes the first impression

    Like I said, your website is the first thing a potential client sees before knowing your services and how your business works. Those first few seconds are essential in your business because they determines if a potential client would become a client or not. And, it also determines your bounce rate. Would the client leave the site almost immediately? Or would they stay and check your services out?

    An unappealing website or – God forbid – an outdated one would make your audience immediately bounce. This is because first impression matters. What they see first – your branding and website – matters a lot on your business. So you should always keep yourself and your business up to date on the latest technological trends and developments.

    2. Helps your SEO

    A great web design is beyond how great it looks or how easy it is to navigate. Although these two are important on their own, a great web design should also be SEO-friendly.

    A great way to stay on top of your game among your competition is SEO. Let SEO be integrated into your website design from scratch on a long-term basis, and watch as your website improves its rankings in search engines like Google or Bing.

    If you don’t know how to integrate SEO into your website, do not leave it for a latter period. Instead, get a professional web developer who knows what he/she is doing.

    3. Builds up the character for your company

    How your website looks and feels to your audience is how they perceive the customer service to be. For example, when you enter a company for the first time, several things happens. You get recognised as a potential client, and immediately get attended to by the receptionist. The receptionist further directs you to either the waiting room or the person in charge directly.

    If you get transferred to the waiting room, you would be given certain refreshments – like coffee or tea – depending on your preference. And when you finally meet the person who would handle your request, the manner at which he/she treats you, their character, is what makes you stay or leave.

    The same thing goes for websites. Your website tells a potential client how the character of the company is. So you have to ask yourself, is your website user-friendly? Natural? Welcoming? Easy to navigate through? And most importantly, is it SEO-friendly, so that more clients can find your business?

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    Source by Karina Popa

    Views: 0

  • Problems Encountered by Nigerian Entrepreneur and Possible Solutions

    Problems Encountered by Nigerian Entrepreneur and Possible Solutions

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    The success enjoyed by most industrialized countries can be attributed to the role played by technological innovation and entrepreneurship, both of which continue to drive their economies today. These two factors are seen as key components for the industrialization and development of African countries. The Nigerian government has recognized this fact and has taken measures aimed at promoting and cultivating the entrepreneurial culture in our country. Through the Nigerian Investing Commission (NIC), our government has in the past introduced a policy that required university students regardless of their area of study to take courses in entrepreneurship. While our government is putting extra effort in promoting entrepreneurship in Nigeria, there are still a number of problems that a Nigerian Entrepreneur faces. Below are some of the problems encountered and possible solutions.

    * Diversifying the Economy

    Though our country’s economy has over the last couple of decades relied heavily on its oil production, we must find ways to diversify our economy and avoid the over reliance on oil. Like other developing countries, Nigeria is facing an increase in its unemployment rate that is now at 6 % and is on the increase, with many graduates finding it hard to get jobs while most of those who get jobs are underemployed. This coupled with the global financial crisis in which massive numbers of employees are being laid off; entrepreneurship is seen as an essential key if we want our country to achieve its ambition of being an industrialized nation by the year 2020.

    * Unfriendly Business Climate

    Being an entrepreneur in Nigeria requires great determination as practicing and potential business owners are faced with countless challenges. Nigerian’s business climate should be made welcoming to those in the Micro, Small and Medium Enterprises (MSMEs). The role played by these MSMEs should not be underestimated since majority of the thriving businesses fall in this category and for us to achieve our goals, adequate attention and support must be directed towards these institutions. To be able to help and protect entrepreneurs, we must first have a clear idea of the challenges facing our entrepreneurs in their pursuit of making Nigeria a prosperous country.

    * Lack of Credit Facilities

    Potential Nigeria entrepreneurs go through many hardships when trying to access credit for their businesses. Though there is a wide range of financial institutions that offer business loans, they usually charge high interest rates deterring aspiring entrepreneurs. For instance, major banks have pegged their lending rates to as much a 28% deterring potential entrepreneurs who are mostly low income earners. Other obstacles faced by our entrepreneurs include severe collateral conditions set by banks and other lending institutions. Though our government through the Central Bank and the Banker’s Committee came up with guidelines requiring banks to set aside 10% of their profits for funding MSMEs, majority of these banks have been reluctant to do so. This has led to the emergence of micro-finance institutions which though helpful are not sufficient for meeting the financial requirements.

    * Multiple Taxation

    One other sensitive challenge that is encountered by majority of Nigerian entrepreneurs is multiple taxation. Although we have a responsibility of funding the government through paying taxes, most of the taxes charged on entrepreneurs are not lawful and have the effect of increasing the cost of doing business. Although Nigeria’s Companies Income Tax Act (CITA) has approved only 39 taxes and levies, there are over 500 various levies and taxes that are imposed by state and local government agents. These taxes are questionable and in the case where they are genuine, they are mostly duplicated and this has the effect of increasing the cost of doing business.

    * Poor State of the Country’s Infrastructure

    The state of our infrastructure can be deemed to be a nightmare to both entrepreneurs and the rest of the country’s population. With the existing infrastructure deteriorating and in some places it is non-existent; the cost of doing business has tremendously gone up. The state of the country’s road network makes it hard for entrepreneurs in the agricultural sector to transport harvested produce from farms to processing factories. According to a report released by the World Bank, Nigeria’s pace of socioeconomic development and growth is way below what we can achieve. This is mostly because of the erratic supply of electricity which has negatively affected many businesses. The outcome of power problems has prompted entrepreneurs to generate power through expensive ways that have in turn increased their production costs and made their products uncompetitive due to high prices. Our government should put policies in place to perk up Nigeria’s infrastructure so as to promote successful entrepreneurship.

    * Failure to Adapt to the Changing Business Environment

    Majority of those who venture into MSMEs (Micro, Small and Medium Enterprises) do so because of their need to make money and in almost all cases, such entrepreneurs lack relevant and adequate information about the businesses they engage in. In the event where problems arise, most of these business owners lack sufficient problem solving skills and in the end they find it hard to survive. With the telecommunications sector having grown by about 206.5 % between 2002 and 2004 and is continually expanding, Nigeria has become one of the fastest growing ICT market not only in Africa but also worldwide. This presents a challenge to entrepreneurs who have not embraced technology, and who are now finding it hard to remain relevant in the competitive business environment. For existing and potential MSMEs to survive and be relevant, we must adapt to the changing business environment and embrace technology.

    * Addressing the Challenges

    Solving the problems encountered requires a combined effort by both the entrepreneur and all concerned stakeholders. As Small and medium business owners, we need to increase our knowledge and skills of the market by acquiring relevant and up to date education particularly in your area of business. Our entrepreneurs need to collect information about their target market by seeking help from consultants and professionals who have experience in the particular market.

    One strategy that can be used by our small and medium entrepreneurs to remain relevant and competitive in today’s market is to come up with fresh and creative ideas of doing business. Due to the increase in technology, business is fast changing, thus our MSMEs need to constantly re-invent the way they do business.

    There is a great need of creating a strong link between MSMEs and supporting institutions if Nigeria is to fully benefit from such businesses. Though some financial institutions are still reluctant to provide financial assistance to MSMEs, there are some that give out loans at reasonable rates provided the business sounds viable. The key challenge is for our entrepreneurs to prepare sound business proposals. For our country to achieve its goals and stop relying on oil alone, we need to focus much attention needs on the private sector and our government must create a conducive atmosphere for such businesses to thrive and drive the country towards economic prosperity.

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    Source by Peter O Osalor

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  • Digital Medicine Platform for Treatment of Cognitive Disorder

    Digital Medicine Platform for Treatment of Cognitive Disorder

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    Akili, a pioneer in therapeutic prescription digital medicine has closed successfully it’s $55 million financing Series C trial of medicine. This funding follows a successful trial, including study, developing and testing a novel digital medicine named AKL- T01. This flagship product of Akili aimed to treat a type of cognitive disorder- attention deficit/hyperactivity disorder (ADHD). Once approved and launched commercially, it would be the first digital and standalone therapeutic medicine for ADHD. Company’s other product in the pipeline and research, AKL-T02 will treat autism spectral disorder (ASD) or what simply known as autism.

    Autism refers to another type of cognitive disorder, particularly in children, making them difficult to interact socially. The repetitive behavior and underdeveloped speech and verbal communication render them vulnerable in society. The reason behind autism could be genetic as well as environmental influence.

    The above news has brought in a new ray of hope for an autism patient where there is no specific traditional medicine is available for its cure. This new development has the potential for treating this disorder, probably with more efficiency.

    This funding will also help to advance products in the pipeline for treating multi sclerosis (MS) and depression. After approval by the U.S. Food and Drug Administration (FDA), it will be launched commercially for the patients. According to Akili AKL-T01 would be a standalone treatment for ADHD.

    The company’s founder and CEO Eddie Martucci is quite happy with the response of investors and welcomed the financing. He said this financing indicates faith of people in his company’s potential in digital medicines and growth. According to him, the company will continue to grow and supply novel solutions in the redefined healthcare sector.

    Akini Interactive is a company who believes in transforming healthcare through its digital therapeutics medicine solving Neuro-cognitive disorders. It believes in targeting specific cognitive area or nerve which has been suppressed by the dysfunction. The treatment includes, interestingly, not any pill, but customized action video games for patients to play.

    Video games are designed by neuroscientists and entertainer engineered with algorithms to treat a cognitive disorder like depression. According to the company, highly-interactive and highly engaging games provide a therapeutic experience to patients which actually benefit them. Through high-end therapeutics interactive video games, the specific regions of the brain could become functional which has been suppressed by the disorder, improving the condition of the patient. There would second by second tracking of patient’s cognitive response and data available for any improvement in the patient’s condition.

    AKL- T01 if approved by the FDA and then it would certainly indicate towards the acceptance of new healthcare solutions for patients. It has the capability to transform the whole healthcare process and system in coming years. This funding will boost the confidence of other investors, which are planning to invest or come together for such digital medicine research and development in the future and those patients who are searching for new areas to treat disorders like autism could be more than happy to read such positive news.

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    Source by Shalini Madhav

    Views: 0

  • Entrepreneurship Development

    Entrepreneurship Development

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    Who is an entrepreneur?

    An entrepreneur is someone who manages and organizes any form of business. Who has the capability to take initiatives, motivate others, work in a team, and become a leader. He is a man who starts his own venture not seeking for a job but providing many people a hope of life.

    Why Entrepreneurship?

    Entrepreneurship plays an important role in case of economic development of a country. A lot of problems of our country would be solved if people will start considering entrepreneurship as the first option for their career.

    Employment:

    One of the greatest problems of our country is “Unemployment”. Let’s see how entrepreneurship tackles with this problem.

    Current employment opportunities can only cater 5 – 10 % of population. Entrepreneurs generate employment both directly and indirectly, directly by self employment as an entrepreneur and indirectly by starting many industrial units where they offer jobs to millions of people. Thus entrepreneurship is the best way to fight with the evil of unemployment.

    National Income

    National Income consists of the goods and services produced in the country. The goods and services produced are consumed within the country and can also be exported to other countries. The domestic demand increases with increase in population and increase in standard of living. The export demand also increases to meet the needs of growing imports due to various reasons. An increasing number of entrepreneurs are required to meet this increasing demand for goods and services. The manufacturing rate of any developed country lies between 60% – 70%. But unfortunately in our country this rate is below 40 %. If you want to become a great entrepreneur or want to do something for your motherland, become a manufacturer not just go for a service industry.

    Dispersal of economic power:

    Industrial development normally may lead to concentration of economic powers in a few hands. This concentration of power in a few hands has its own evils in the form of monopolies. Developing a large number of entrepreneurs helps in dispersing the economic power amongst the population. It may help in weakening the harmful effects of monopoly.

    Better standard of living:

    Entrepreneurs play a vital role in achieving a higher rate of economic growth. They are able to produce goods at lower cost and supply quality goods at lower price to the community according to their requirements. When the price of of the commodities decreases the consumers get the power to buy more goods for their satisfaction. There is a great demand of such entrepreneurs who can make this thought possible.

    Creating solutions for society :

    An entrepreneur is a person who creates solutions not only for the problems of his business but for the whole society. Entrepreneurs play a key role for innovations and creative ideas that solve different problems in the world with the efficient use of technology. What is needed? or desired should be created with appropriate use of technology. This gives a clear thought of “Creating solutions with technology!”

    The benefits and needs of entrepreneurship is endless. The greatest demand of today’s world is simply “Be an Entrepreneur!” that will solve economic problems of your family, your society, your people and your country. Let’s create wealth,not just seek for a salary.

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    Source by Mohammed Faizan Ansari

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  • Journey of a Drug: Design to Market Seller

    Journey of a Drug: Design to Market Seller

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    Where do the medicines we take from chemists come from? How do the doctors know which drug is good for which disease? How the medicines really are able to cure a particular ailment they have been prescribed for? Do these questions come to your mind, whenever you buy any medicine?

    Come, let us today know about the medicine development from the beginning …

    The development of medicine is called a Clinical Research and has different Phases. Phases of the clinical research are the steps of experiments with a health intervention in an attempt to find enough evidence for a process which the scientists think would be helpful in medical treatment.

    The pharmaceutical study starts its journey from a drug design and drug molecule discovery which further progresses into animal testing and then human studies to see the drug's effectiveness.

    Drug undergoes many trials- Preclinical, Phase 0, Phase I, II, III and IV. Sometimes combined trials also are undertaken to reduce the time of development, like Phase I / II and II / III.

    Pre-Clinical Study

    When the drug molecule is identified, it undergoes many in vitro ( test tube or cell culture ) and in vivo ( animal ) experiments. These experiments are conducted to know the preliminary efficacy, toxicity, and pharmacokinetics of the various doses of the drug. Many drug molecules are designed at a time and these pre-clinical studies let the pharmaceutical companies decide which molecule has a greater potential in further studies.

    Design of the Studies:

    Trials are always conducted by following the set of steps, called the protocol, developed by the researchers to find the specific questions related to the medical product. Information from the prior studies become the base for the researchers to develop research questionnaire and objectives:

    • Participant selection
    • Number of participants
    • Duration of the study
    • Controlled or not
    • How and what dosage will be given
    • What and when the data will be collected
    • Review and analysis time

    Phase 0 Study

    It is also called micro-dosing trials, 10-15 human subjects are taken and single sub-therapeutic doses are administered to gather the pharmacokinetic ( PK ) data of the drug. This enables the company in deciding to go or no go for the further development of the drug, based on more relevant human data instead of animal data.

    Such trials exceed the speed of promising drug development by establishing whether or not the drug acts on humans as expected in pre-clinical studies.

    After the company decides to take the molecule of the drug forward in development, it will have to submit the data of its preliminary studies to the FDA called Investigational New Drug ( IND ) application filing.

    Phase I Study

    Also called First-in-man studies as these are the first stage of human testing studies. These are the studies which are designed to determine the maximum dose that can be administered without showing adverse effects.

    Contract Research Organizations ( CROs ) conduct such studies in the clinical trial clinics where medical staff provides full-time attention to 2-100 healthy subjects enrolled for the study and collects the data.

    These studies determine the safety ( pharmacovigilance ), tolerability, pharmacokinetics ( PK ) and pharmacodynamics ( PD ) of the drug. The design of Phase I studies is dose-ranging also called dose escalation studies conducted in controlled clinics called Central Pharmacological Units ( CPUs ).

    Usually, healthy subjects are hired but sometimes terminally ill patients like of cancer and HIV and also those who have already tried and failed to improve on existing medications.

    There are two divisions for Phase I study:

    Phase Ia: Single ascending dose

    Phase Ib: Multiple ascending dose

    Phase II Study

    More than 100 diseased subjects are enrolled for a longer period study, to know the benefits of the drug along with its safety which includes genetic testing. These studies are also called as "Proof of Concept or Pilot" studies.

    This is the phase when the drug's development can fail due to toxicity or less than expected results.

    Two divisions of this phase are:

    Phase IIa: Pilot study, to determine the clinical efficacy or the biological activity.

    Phase IIb: Dose-finding study, to check the biological activity with minimal side-effects.

    A combined trial determining the efficacy as well as toxicity are Phase I / II trials.

    Phase III Study

    These are pre-registration trials means the data of this study is submitted to the regulatory agency through New Drug Application (NDA) for its registration. Also called Pre-marketing or Pivotal trials.

    Such studies are multicentral, randomized, in large diseased population ( more than 500 ) with much longer duration of treatment and short follow up period, to determine the long-term safety and efficacy of the drug.

    Even if the regulatory submission is pending, the drug is received by the patients in case it's a lifesaving drug until the drug can be purchased.

    'Label expansion' that is drug can treat an additional disease, other than the disease for which the drug is already approved, may also be the reason for running the Phase III trial.

    It is said that for FDA ( United States Food and Drug Administration ) and MHRA ( United Kingdom's Medicines and Health products Regulatory Agency ) needs at least two trials of successful trials data to register the drug.

    After these trials, the drug is approved for market selling.

    Phase IV Study

    These are Post Market Safety Monitoring studies done after the drug is registered. Also called Late Phase or Confirmatory trials.

    This kind of study determines the long-term adverse effects on the much larger population for a very long duration (at least 2 years). If harmful effects are detected in this study, then the drug is disapproved and the company has to retrieve the drug from the market as it can no longer be sold.

    The entire journey of the drug from a molecule to a market selling product takes around 15-20 years.

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    Source by Nidhi Sharma

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