Tag: Combinations

  • Medical Product Alert N° 1/2020 (English version)

    Medical Product Alert N° 1/2020 (English version)

     

    Falsified antimalarials in West and Central Africa displaying an outdated WHO Essential Drugs Programme logo

    This Medical Product Alert relates to a series of confirmed falsified antimalarials circulating in West and Central Africa. Medicines subject of this alert display a similar logo to the outdated
    WHO Essential Drugs Programme logo.
     

    Since 2013, different falsified medicines, all displaying the outdated WHO Essential Drugs Programme logo, have been reported to the WHO Global Surveillance and Monitoring System by various stakeholders. The continued and widespread availability of these falsified medicines highlights a strong need for additional vigilance. WHO previously published two alerts on this issue (No.132 in Oct 2014, and No.131 in March 2014)

    This WHO medical product alert N°1/2020 refers to falsified Quinine Sulphate 300mg presented in six different combinations of batch numbers, expiry and manufacturing dates (see Table 1). The fraudulent use of the outdated WHO Essential Drugs Programme logo may create a false sense of product quality.

    Table 1: List of identified falsified Quinine Sulphate 300mg, subject of WHO Alert N°1/2020

    Medical Product Alert N° 1/2020 (English version) 1

    Recently received results of analysed samples show they do not contain any of the expected active ingredients.

    Quinine sulphate is referenced on the WHO Model List of Essential Medicines, to manage and treat severe malaria. At this stage, no adverse reactions attributed to these falsified products have been reported to WHO.    

    All the above falsified products claim to be manufactured by REMEDICA LTD – Cyprus and to contain 300mg of quinine sulphate. Remedica Ltd has confirmed that:

    • they did not manufacture the above falsified products; and
    • the variable data (batch number and dates) on the above products has never been used by Remedica.

     These falsified medicines display the following common characteristics (please see photographs):

    • grey or white plastic containers which contain 1000 loose circular tablets each;
    • display the outdated WHO Essential Drugs Programme logo;
    • English and French labelling with mistakes and inconsistencies; and
    • discovered at patient level in both regulated and unregulated outlets.

    Product details, photographs and advice to the public are available on the following pages.

    Outdated WHO Essential Drugs Programme logo 

    Medical Product Alert N° 1/2020 (English version) 2

    Photographs of confirmed falsified Quinine Sulphate 300mg tablets subject of
    Medical Product Alert N°1/2020

    1.       Falsified
    Quinine Sulphate Tablets B.P 300mg
    identified
    in Chad (Batch 44680)

    Medical Product Alert N° 1/2020 (English version) 3

     

    Medical Product Alert N° 1/2020 (English version) 4

    Medical Product Alert N° 1/2020 (English version) 5Medical Product Alert N° 1/2020 (English version) 6Medical Product Alert N° 1/2020 (English version) 7

    Medical Product Alert N° 1/2020 (English version) 8

     

    WHO requests increased vigilance within the supply chains of countries likely to be affected by these falsified products. Increased vigilance should include hospitals, clinics, health centres, wholesalers, distributors, pharmacies and any other suppliers of medical products.

    If you are in possession of the above products, please do not use. If you have used these falsified products, or if you suffer an adverse event having used these products, please seek immediate advice from a qualified healthcare professional, and ensure they report the incident to your local Ministry of Health/National Medicines Regulatory Authorities/National Pharmacovigilance Centre.

    All medical products must be obtained from authentic and reliable sources. Their authenticity and condition should be carefully checked. Seek advice from a healthcare professional in case of doubt.

    National health authorities are asked to immediately notify WHO if these falsified products are discovered in their country. If you have any information concerning the manufacture, distribution, or supply of these products, please contact rapidalert@who.int . 

    WHO Global Surveillance and Monitoring System

    for Substandard and Falsified Medical Products

    For further information, please visit our website: www.who.int/medicines/regulation/ssffc/en/

     

    Medical Product Alert N° 1/2020 (English version)
    Read More
    https://www.who.int/news-room/detail/09-03-2020-medical-product-alert-n-1-2020-english-version

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  • Ancient Medicinal Wisdom: Vedic Healing With Coriander

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    In Ayurveda, the rasa or taste of coriander is initially sharp or astringent. Digestion mellows this to sweetness.

    What is Ayurveda?

    This is the ancient medical system of India. Ayurveda postulates that there are three basic types of energy or doshas: Vata dosha or wind energy, Pitta dosha or fire energy, and Kapha dosha or water energy. Every individual, (indeed, all matter), is made up of different degrees and combinations of these doshas. This is called the prakriti or constitution of the individual.

    Ayurvedic belief is that coriander, seeds as well as the plant, is beneficial to all body types or doshas as it does not arouse pitta like most other spices.

    Coriander leaves, seeds and powder are used extensively in Indian kitchens because of their appetising aroma. Ancient Ayurvedic practice had recognized the benefits of coriander: the use of these seeds and powder is rooted in this.

    Multiple benefits of Coriander:

    • These seeds contain dietary fibre and this aids in good bowel movements. It also helps in removing intestinal gas and prevents nausea. Coriander seeds can be dry roasted, powdered and added to most dishes; it’s not all about flavor, they are a good digestive aid. Ayurveda tells us so!
    • It will stimulate appetite by helping to produce digestive enzymes and aid in the breakdown of food.
    • It is also good for liver function. This is probably why it is a good appetite stimulant.
    • Coriander powder and seeds do not arouse pitta. In modern scientific terms, coriander is alkaline. Thus, it is good for urinary tract infections. It is also a mild diuretic.
    • These are an age-old cure for menstrual cramps: just boil 1-2 teaspoons of coriander seeds in half a litre of water, add a teaspoon of organic sugar and drink warm. The relief is palpable.
    • Ayurveda has always known it; now modern research shows coriander seeds to inhibit bacterial growth thus making them a good anti-bacterial agent. This inhibitive property makes coriander a good fighter of stomach infections.
    • Anti-bacterial coriander is also a good anti-fungal. Coriander seeds are quite useful in fighting skin problems like eczema, itchy skin, and rashes.
    • It contain linoleic acid which is why they provide pain relief as well as act as an anti-inflammatory. This property also makes them useful in curing mouth ulcers and sores.
    • Ayurvedic cures for chronic conditions like arthritis make liberal use of coriander seeds/powder. A ‘tea’ is made by boiling ground coriander seeds in water and drinking the warm decoction.

    Here are some Ayurvedic recipes for different ailments which make generous use of coriander seeds:

    • That parched feeling that a fever causes can be relieved by boiling 1 teaspoon of coriander powder in 1 cup of water. Drink after cooling, and your thirst will vanish.
    • For fatigue or a burning sensation in the body, soak a teaspoon of coriander seeds in a glass of water. Let it stand overnight. Strain and drink first thing in the morning.
    • Boil 1 tsp of coriander seeds in half a litre of water. Let it stand for 10 minutes. Strain and drink. This relieves any burning sensation while urinating.
    • Do not pop a pill at the first signs of malaise.The harmful effects of unnecessarily medicating yourself can be controlled by these simple home remedies which carry the goodness of Mother Nature. Ayurveda views human beings as an integral part of larger creation and treats human ailments non-aggressively.
    • When medicines should be used with circumspection, what can one say about the harmful chemicals that we ingest every day unknowingly? Food production in the modern day is fraught with dangerous practices. The indiscriminate use of chemical methods of farming is poisoning almost everything we eat. The organic movement aims to reverse this. If you want to enjoy the maximum benefit of any food product, GO ORGANIC. Coriander is no different.
    • Terragreens Organic is a store of the freshest and most natural ingredients, untouched by chemicals. Enjoy the full benefit of this miracle of Mother Nature. Buy your coriander seeds or powder from the best!

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    Source by Karthik Guduru

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  • Old World Style Kitchen Designs

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    With the emergence of new styles and modern amenities, today’s kitchens have undergone complete transformation. Along with the appliances, the set ups of the tiles, boards and kitchen counters also have been reformed. Even so, there are certain individuals who prefer to give their kitchens an authentic and traditional look and hence, the Old World style kitchens have been successful in sustaining their standing.

    Old World kitchens were designed in a unique manner. They typically were heavily decorated with distinctive door styles, layered finishes, and stacked with moldings to provide a visual feast. The most frequently used wood for the Old World furniture was either Oak or Cherry. The Old World style kitchen accessories included copper posts, baskets, chopping blocks, crocks, and antique serving pieces. The floors were made either of tiles or wood finishing. The wood and tile finishing differed in darkness level, distressing, sandthrough, paint, and edging. The walls of the kitchen were painted with faux finishes, stucco, or textured finishes. The hardware was filled with hammered distressed iron pieces, and heavy bulky pieces. The kitchen designs usually consist of hearth like cooking centers, loose furniture pieces and tables used as islands, but had ample of open storage areas.

    The Old World style kitchens incorporated moldings from the ceiling in large stacked molding combinations, crown posts, large arches, or beamed ceilings. The countertops of such kitchens were preferably in any of the three options of stone, rustic tile and wood.

    The Old World style kitchens were more suitable for big and large households and were not affordable styles for small homes. The original beauty of these kitchens can be still seen in some houses, which were built in the 1800s. They are often termed as dark ages kitchens because of the antique and ancient feel they provide to the entire house.

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    Source by Damian Sofsian

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  • Marital Discord in Astrology

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    People normally say that a marriage has been settled in haven and is performed at the earth. It is seen that a married person is leading a very peaceful, prosper and comfortable life, but many are such who are weeping over married life and consequent upon this tension. All these are because of mismatch and adverse compatibility.

    Marital discord is a universal problem all over the world. The reasons can be many including the economical, lack of physical and psychological compatibility, extra-marital relationships, aggressive attitudes, selfish nature, over ambitions etc.

    Astrology can accurately reveal the ins and outs of human life, and therefore, can advice beneficially. Definitely, it has immense value, for astrology can give true guidance and advice regarding one’s marriage.

     

    Basic Factors Responsible for Marital Discord

     

    ·       Strength of ascendant

     

    ·       Moon—revels the desires of human mind

     

    ·       Venus—revels sexual appetite, love, desire, and happiness

     

    ·       Mars—assists in strengthening the sexual instincts in the ease of marriage or to help to establish sexual relationship.

     

    ·       Jupiter—significator of husbands for women

     

    ·       Sun/Saturn/Rahu— fiery, separative in nature

     

    ·       2nd house—denotes family

     

    ·       5th house — love affairs and marriage following intercourse

     

    ·       7th house— stands for love and matrimony,

     

    Wife/husband/law suits, partnerships.

     

     Different Combination for Marital Discord

    ·       Weakness of 2nd /7th houses because of planets present in the house or the lords of house are

     

    1.   Malefic in nature

     

    2.   Inauspicious placement of lords

     

    3.   Combust

     

    4.   Debilitated

     

    5.   Are in infancy or old -age state

     

    6.   Afflicted by functional malefic nodes [Rahu/Ketu]

     

    7.   Sandwiched between malefic planets

     

    ·       2nd /7th houses or their lords afflicted by the separative planet like Sun/Saturn/Rahu.

     

    ·       6/8 placement of 1st/7th lords—separation/divorce/break of agreement.

     

    ·       If lords of 1st/ 7th/2nd and Venus are occupying unfavourable houses/combust/debilitated/in enemy sign misfortune will happen after marriage.

     

    ·       Venus and Mercury in 7th house make a person of loose morals and drag to have extra marital relations.

     

    ·       Mars when debilitated and forming relationship with 1st/7th houses or their lords, make the person aggressive and ill tempered.

     

    ·       Node or Rahu/Ketu joining closely Mars makes native/spouse stray and that becomes the reasons for the discord.

     

    ·       The ascendant/Moon of husband/wife in inimical signs sows the seeds of inharmonious relations.

     

    ·       Afflicted or weak Jupiter shows selfish nature of married partner.

     

    ·       6/8 placement of Venus and Moon denotes disputes in love and marriage.

     

    ·       Aspect of at least two retrograde planets on 1st/7th houses/lords.

     

    ·       Saturn and Rahu/Mars and Rahu/Sun and Mars combinations afflicts 1st/7th denotes disputes and discords.

     

    ·       8th/12th lords occupy 3rd house, and 7th house with nods/malefic planets, divorce or separation takes place. 

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    Source by Geeta Jha

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  • Creativity and Entrepreneurship

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    We will commence our assignment with a discussion of sources of new ideas. We will then examine methods of generating ideas, creative problem solving, the product planning and development process, and then e-commerce. We will then generate several new ideas using brain writing, the checklist method, and free association. We will apply the product development stage to our new ideas and end our discussion with two alternatives to e-commerce.

    Sources of new ideas include consumers, existing products and services, distribution channels and even the Federal Government (Hisrich, 2008). The files of the patent office are full of new ideas and new product ideas can form as a result of government regulations. Research and development is the largest source of new ideas and can occur in a formal lab or in a garage or basement.

    Many methods can be use to generate new ideas. In focus groups, a moderator leads a group of people through open, in-depth discussions. These groups generally consist of eight to fourteen participants. They are stimulated by comments from other group members in creatively conceptualizing and developing a new product idea to fill a market need. Focus groups are also an excellent way to screen ideas and concepts. Problem inventory analysis is another great method of generating new ideas. It uses individuals in a manner that is similar to that of focus groups. Consumers are provided with a list of problems in a general product category and are then asked to identify and discuss products in this category that have the particular problem. This method should be used primarily to identify product ideas for further evaluation.

    Creative problem solving takes the generation of new ideas to a higher level. Brainstorming allows people to be stimulated to greater creativity by meeting with others and participating in organized group experiences. Rules include the following:

    a) Criticism not allowed

    b) Freewheeling is encouraged

    c) Quantity of ideas is desired

    d) Encourage combinations and improvements of ideas

    Brainstorming should be fun and not contain any domination or inhibition of discussion. It is highly effective in groups of six to twelve individuals and can generate ideas about a problem within a limited time frame through the spontaneous contributions of participants. Reverse brainstorming offers a different perspective as it is similar to brainstorming, except criticism is allowed. It is based on finding fault by asking in how many ways an idea can fail. The focus is on the negative aspects of a product, service, or idea. One must be careful to maintain group's morale though. Reverse brainstorming can be used prior to other forms of creative techniques to stimulate innovative thinking and involves the identification of everything wrong with an idea. It is usually worthwhile since is easier for people to be critical about an idea instead of coming up with a new one.

    Brainwriting is a form of written brainstorming and gives participants more time to think than brainstorming. It is silent and each group member writes down three ideas within five minutes. A form is passed around to all participants while a leader monitors time intervals and can even modify them. The Gordon method is another method of creative problem solving and begins with group members not knowing the exact nature of a problem. This ensures that a solution is not clouded by preconceived ideas and behavioral problems. A general concept associated with the problem is mentioned and the group then expresses a number of ideas. A concept is then developed and related concepts are developed. Finally, the actual problem is revealed.

    The checklist method involves the development of a new idea through a list of related issues or suggestions. The following questions demonstrate how the checklist method is used:

    ii.Put to other uses? New ways to use as-is?

    iii.Adapt? What else like this? What could I copy

    iv.Modify? New twist? Change meaning, color, form, shape?

    v.Magnify? What to add?

    vi.Minify? What substitute? Smaller?

    vii.Substitute? What else instead? Other material?

    viii.Rearrange? Other pattern?

    ix.Reverse?

    x.Combine? Blend?

    Free association is another form of creative problem solving and is one of the simplest and yet most most effective methods. It is helpful in developing an entirely new slant to a problem. First, a word or phrase related to a problem is written down. Then other ones are written down and so on. Each new word attempts to add something new to the ongoing thought processes. This creates a chain of ideas ending with a new product idea.

    The product planning and development process is crucial to an entrepreneur's success. One must first establish evaluation criteria by assessing the market opportunity and size. One must evaluate current competing producers, prices, and marketing efforts. New idea should have synergy with existing management capabilities and marketing strategies. The proposed product or service idea should be able to be supported by and contribute to a company's financial well-being. One should evaluate the compatibility of a new product's production requirements with existing plant, machinery, and personnel. Entrepreneurs should be concerned with formally evaluating an idea throughout its evolution. The idea stage involves identifying new product or service ideas while eliminating impractical product or service ideas.

    One must determine the need for the new idea as well as its value to the company to ensure both prior to proceeding with the ideas. The need determination should focus on the type of need, its timing, the users involved with trying the product or service, the importance of controllable marketing variables, the overall market structure, and the characteristics of the market. In the concept stage, a new product should be developed further and refined through interaction with consumers. The refined idea is then tested to determine consumer acceptance. Features, price, and promotion should be evaluated for the concept being studied and any major competing products. The product development stage involves determining consumer reactions to the physical product. An entrepreneur can provide samples in this stage. The final stage of the development process consists of the test marketing stage, which provides actual sales results that indicate the acceptance level of consumers.

    E-commerce is a relatively new concept in the business world and should be used creatively. An entrepreneur must address additional specific issues due to continually-evolving technology. For instance, one must decide if he will run the internet operations of the business or outsource the task to another firm. A website is often created and must be aesthetically-pleasing and fully functional. Ninety percent of small businesses use websites and ease of use is important with websites. The website is a communication vehicle in which search capability and speed are equally important. A website should have a shopping cart, secure server connection, credit card payment processing, and a customer feedback feature. It should be customized for specific target market groups and should be compatible with various browsers.

    The tracking of customer information is vitally important when dealing with e-commerce. This is often accomplished via electronic databases. Doing so supports personal marketing and captures customer attention with customized one-to-one marketing. It is critically important to protect the privacy of individuals when keeping databases.

    When conducting e-commerce as an entrepreneurial company, one's products should be able to be delivered economically and conveniently. Products must be interesting to a large number of people and a company must be prepared to ship products out of its geographic location. Online operations must bring significant reductions in cost as compared to having a store.

    We now turn our attention to the generation of clothing ideas for Libya. We utilized brainwriting with a time limit of five minutes to come up with a new idea. We drafted an adjustable robe for women that can be rolled up and then attached with velcro to shorten it when desired to offer additional clothing and styling capabilities. We then used the checklist method and came up with the following:

    xi.Modify? New twist? Change meaning, color, form, shape?

    a) Can offer robe in multiple colors such as white, red, and blue

    xii.Substitute? What else instead? Other material?

    a) Can make robes out of breathable polyester / nylon material as used in athletic wear

    b) Allows for wicking away of sweat and moisture to keep clothing dry and light in weight

    We then used free association to come up with a list of related words:

    -xiii.cooling, light weight, windproof, light colors, reflective material xiv. End result is metallic-colored fabric that will reflect sunlight like aluminum foil

    We then applied product development stages to the new ideas to formulate a final product concept. We first established our evaluation criteria by assessing market opportunity and size. The population of Libya is 6,173,579, so this will serve as our potential market (Wikipedia, 2009). We then turned to the idea stage to identify new product ideas. These ideas included the following thought process:

    a) Can offer robe in multiple colors such as white, red, and blue

    b) Can make robes out of breathable polyester / nylon material as used in athletic wear

    c) Roll-up velcro to shorten robe for greater cooling and comfort

    d) metallic-colored fabric that will reflect sunlight like aluminum foil

    xv.Eliminate impractical product / service ideas in this stage

    a) Metallic-colored fabric will be eliminated

    b) Reflecting sun can create an oven effect on wearer

    c) Can actually make customer hotter and not cooler

    xvi.Determine the need for the new idea as well as its value to the company to ensure both prior to proceeding with ideas

    a) Multiple robe colors will appeal to different people

    b) Wicking-material robe will appeal to men more

    c) Roll-up robe will appeal to women more

    d) Can result in greater sales and market share

    e) Is beneficial to company to sell more robes while meeting individual needs of customers via mass customization

    We then moved on to the concept stage to further develop and refine our new product ideas through interaction with consumers. We plan on participating in trade shows to present our new ideas. We will display prototypes and obtain feedback from potential customers. Our refined ideas will then be tested to determine consumer acceptance. We will take consumer ideas into consideration and tweak prototypes accordingly. We will then consider the pricing and products of our competition and price our products accordingly to maintain a competitive edge. In the product development stage, we will determine consumers' reactions to the physical product by allowing customers to try our robes on at trade shows. We will then participate in the test marketing stage by proving actual sales results once our products enter the market.

    Alternatives for the use of e-commerce in conducting one of the product development stages for the actual commercialization of our final product idea can involve the creation of a company website that is easy to use. We will incorporate powerful search capabilities while ensuring that our site performs with acceptable speed. We will include a shopping cart, secure server connection, credit card payment, and customer feedback feature in our website. In addition, our website will be customized for specific target market groups and be compatible with various browsers. We will also track customer information by creating an electronic database that supports personal marketing. This will allow us to capture customers' attention with customized one-to-one marketing while protecting the privacy of individuals via strong database encryption. Incorporating online operations will bring significant reductions in cost as compared to having a store. This will allow us to pass savings on to customers via lower prices and greater value.

    Bibliography

    Hisrich, Robert D., Peters, Michael P., and Shepherd, Dean A. (2008). Entrepreneurship
    (7th ed.). Boston: McGraw-Hill Irwin.

    Wikipedia (2009). Libya. Retrieved July 23,2009 from http://en.wikipedia.org/wiki/Libya .

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    Source by Bobby Mobini

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  • Astrological Combinations For Riches

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    There are various combinations for the riches in the horoscopes. Let us see which are the combinations for the big riches.

    A person born in a poor family having the following combination in the horoscope is sure to be a very rich person:-

    1. Jupiter is in the Quadrant in Cancer, Saggitarius or Pisces signs.

    2. Moon is in the 2nd, 8th, 10th or 11th house, in the sign of Taurus, Cancer, Saggitarius or Pisces signs.

    3. Mercury is in 2nd or 10th houses in the sign of Gemini or Virgo.

    4. Mars is in the 4th, 10th or 11th house in the sign of Capricorn.

    5. Venus is in the 2nd, 9th, 10th or 11th house in the sign of Taurus, Libra or Pisces.

    6. Saturn is in the 4th, 5th or 11th house in the sign of Acquarius or Libra.

    Saggitarius or Pisces

    If the Ascendent is Aries or cancer:- And the Sun is in the Ascendent, 3rd, 10th or 11th house and Saturn is in the 4th or 7th house in Libra,and Mercury and Venus are in 2nd house in Taurus then, the native is bound to be a very rich person.

    If the lord of Quadrent is in the Trine and Lord of Trine is in the Quadrent, or both are either in the

    Quadrant or in the Trine, the native is a very rich person.

    If a native has Cancer as his Ascendent and has Saturn in the 4th house (Libra), Mars in the 7th house

    (Capricorn), Sun in the 10th house (Aries), he is also very rich.

    Astrologically, in a horoscope the lord of 11th house is the main planet to give income.

    A person will become very rich, through share market or speculation, if saturn is positioned in the 11th house in signs Libra or Acquarius.

    If Saturn (in sign Libra), or Mercury (in sign Virgo) or Moon (in sign Taurus) is positioned in the 11th house, the native earns huge wealth through the manufacture of machineries.

    Besides, in a horoscope, the 2nd house is the house of wealth.

    If the 2nd house is positioned by Venus in Taurus or Pisces, the native, becomes very rich through the

    business of white commodities like Silver, Cotton, Cotton Mills, Sugar.

    In a horoscope, 5th house is the house of speculation. If the 5th house is positioned by the Sun (in the signs Aries or Leo) or Jupiter (in the sign Cancer or Saggitarius), the native will get the huge money from race course and/or lotteries.

    In a horocope the 10th house is the house of Karma,

    If Saturn is situated in the 10th house in the sign of Libra or Acquarius,the native becomes rich through the business of oils.

    In a horoscope, the 8th house is the 11th (house of gains) from the 10th house (house of Karma), which if positioned by planets Moon (in sign Taurus), Mercury (in sign Virgo), Jupiter (in sign Cancer) or Venus (in sign Pisces), the native earns through speculation.

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    Source by Shashi Sharma

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