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Tag: Clinical

  • WHO to accelerate research and innovation for new coronavirus

    WHO to accelerate research and innovation for new coronavirus

    WHO is convening a global research and innovation forum to mobilize international action in response to the new coronavirus (2019-nCoV). 
    “Harnessing the power of science is critical for bringing this outbreak under control,” said WHO Director-General Dr Tedros Adhanom Ghebreyesus. “There are questions we need answers to, and tools we need developed as quickly as possible. WHO is playing an important coordinating role by bringing the scientific community together to identify research priorities and accelerate progress.”
    The forum, to be held 11-12 February in Geneva, is organized in collaboration with the Global Research Collaboration for Infectious Disease Preparedness.
    The forum will bring together key players including leading scientists as well as public health agencies, ministries of health and research funders pursuing 2019-nCoV critical animal health and public health research and the development of vaccines, therapeutics and diagnostics, among other innovations. 
    Participants will discuss several areas of research, including identifying the source of the virus as well as sharing of biological samples and genetic sequences.
     
    Experts will build on existing SARS and MERS coronavirus research and identify knowledge gaps and research priorities in order to accelerate scientific information and medical products most needed to minimize the impact of the 2019-nCoV outbreak.  
    The meeting is expected to produce a global research agenda for the new coronavirus, setting priorities and frameworks that can guide which projects are undertaken first. “Understanding the disease, its reservoirs, transmission and clinical severity and then developing effective counter-measures is critical for the control of the outbreak, to reduce deaths and minimize the economic impact,” said Dr. Soumya Swaminathan, WHO Chief Scientist.
    This will also fast-track the development and evaluation of effective diagnostic tests, vaccines and medicines, while establishing mechanisms for affordable access to vulnerable populations and facilitating community engagement.
    “The WHO R&D Blueprint is a global strategy and preparedness platform that drives coordinated development of drugs and vaccines before epidemics, and allows the rapid activation of R&D activities during epidemics. It speeds up the availability of the diagnostics, vaccines and treatments and technologies that ultimately save lives,” added Dr Michael Ryan, Executive Director, WHO Health Emergencies Programme.  
    Setting clear global research priorities for the novel coronavirus should lead to more efficient investments, high-quality research and synergies among global researchers.

    WHO to accelerate research and innovation for new coronavirus
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    https://www.who.int/news-room/detail/06-02-2020-who-to-accelerate-research-and-innovation-for-new-coronavirus

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  • It’s time to consider propranolol as an anti-cancer drug, researchers say

    It’s time to consider propranolol as an anti-cancer drug, researchers say

    Propranolol, a beta-blocker commonly prescribed to treat irregular heart rates and other conditions, has significant anti-cancer properties, say researchers in a new clinical study published in ecancermedicalscience.

    The Repurposing Drugs in Oncology (ReDO) project, an international collaboration between the Anticancer Fund, Belgium, and US based GlobalCures, says that existing and widely-used non-cancer drugs may represent a relatively untapped source of novel therapies for cancer.

    Historically, pharmaceutical companies devote little time to “repurposing” existing drugs. The ReDO project hopes to change that, raising awareness by publishing a series of articles in ecancer to share evidence for using these therapies in cancer medicine.

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  • E-cigarette vapor does not cause oxidative stress in viable lung epithelial cells

    E-cigarette vapor does not cause oxidative stress in viable lung epithelial cells

    E-cigarette vapour is much less harmful to lung cells than cigarette smoke. Lab tests show that, unlike tobacco smoke, which causes oxidative stress and cell death, e-cigarette vapour does not. Oxidative stress and cell death are driving factors in the development of many smoking-related diseases such as COPD and lung cancer.

    Vapour from e-cigarettes has been found to contain significantly lower levels of the toxicants found in cigarette smoke (Chemical Research in Toxicology DOI: 10.1021/acs.chemrestox.6b00188), but suitable lab tests and clinical studies are necessary to understand whether this translates into reductions in biological responses and disease.

    Researchers at British American Tobacco have developed a standardized way of measuring and comparing the potential of conventional cigarette smoke and e-cigarette vapour to cause oxidative stress in an in vitro model of lung epithelium.

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  • Overweight and obese type 2 patients show improvements with structured nutrition therapy

    Overweight and obese type 2 patients show improvements with structured nutrition therapy

    Researchers at Joslin Diabetes Center have announced the results of a study that may change how nutrition therapy is delivered to overweight and obese patients with type 2 diabetes. The “Nutrition Pathway Study” compared three models of nutrition therapy and found that a highly structured nutrition plan provides the most significant impact on A1C, body weight and lipid profiles. The study results were presented at the American Diabetes Association’s 76th Scientific Sessions in New Orleans, Louisiana.

    Participants in the structured nutrition therapy arm of the study reduced A1C by an average of 0.67 percent and reduced body weight by an average of 3.5 Kg over 16 weeks. According to Osama Hamdy, M.D., Ph.D., Medical Director of the Obesity Clinical Program at Joslin Diabetes Center and lead investigator on the study, these results were achieved without increasing exercise, changing medications or undertaking behavioral changes.

    “This drop in A1C due to nutrition therapy alone is much better than what we have been able to achieve with many of the current medications for type 2 diabetes ,” said Dr. Hamdy. “This is very encouraging since participants in the study have lived with type 2 diabetes for more than 10 years and were not able to control their blood glucose or weight with multiple medications.”

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  • Changes needed to increase access to colorectal cancer screening

    Changes needed to increase access to colorectal cancer screening

    Colorectal cancer is the second highest cause of cancer death in the United States, expected to claim the lives of an estimated 49,190 people in 2016. The Affordable Care Act (ACA) aimed to increase access to CRC screening by not holding patients responsible for all costs of the procedure, yet current Medicare insurance beneficiaries lacking supplemental insurance may not be able to afford colon cancer screening and treatment. This policy disproportionally puts low-income Americans at risk and adds unnecessary strains on overall health care costs, according to a commentary in the May issue of the journal Gastroenterology.

    “Study after study shows that screening saves lives,” said Chyke A. Doubeni, MD, MPH, chair and the Presidential Associate Professor of Family Medicine and Community Health at the Perelman School of Medicine at the University of Pennsylvania, and lead author of the commentary. “Yet many of those in the group most affected by this deadly disease are unable to afford the screening they critically need. We must renew efforts to ensure equitable access to and use of disease prevention, detection, and treatment services for colorectal cancer.”

    For CRC screening, a full colonoscopy is necessary, where the doctor inspects the rectum and entire colon through a flexible lighted tube, and can remove any abnormal growth. The entire colon has to be cleansed before the colonoscopy, for which the patient is usually sedated

    There are currently an estimated 55.5 million Medicare beneficiaries in the U.S. A 2010 Kaiser Family Foundation survey found that 14 percent lacked supplemental coverage. Until recently, colon cancer screening has been viewed as a one-time activity, while in practice, screening is a series of clinical activities to identify and test patients and perform diagnostic confirmation when necessary. This series of tests and steps include a diagnostic workup, which can include a biopsy to obtain a tissue sample or polypectomy, in which polyps are removed to prevent them from becoming cancerous.

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  • Despite efforts, childhood obesity remains on the rise

    Despite efforts, childhood obesity remains on the rise

    The alarming increase in U.S. childhood obesity rates that began nearly 30 years ago continues unabated, with the biggest increases in severe obesity, according to a study led by a Duke Clinical Research Institute scientist.

    “Despite some other recent reports, we found no indication of a decline in obesity prevalence in the United States in any group of children aged 2 through 19,” said lead author Asheley Skinner, Ph.D., associate professor at Duke. “This is particularly true with severe obesity, which remains high, especially among adolescents.”

    Skinner, along with colleagues at the University of North Carolina at Chapel Hill and Wake Forest University, analyzed data from the National Health and Nutritional Examination Survey, a large, ongoing compilation of health information that has spanned decades.

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  • Can Foam And Latex Pillows Be Dangerous To Your Health?

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    Memory foam pillows and latex pillows are the latest craze in pillow town. You couldn’t blame people who rush out to buy a set for themselves and the whole family. They’re extremely comfortable and without doubt provide excellent support that traditional pillows lack of. Other than they are a dream to sleep on, they are very economical as they last for years. Opposed to most pillows in the market, they don’t go flat over time. And you are guaranteed of pillows that are good as new every day for the years to come. That’s because of the technology applied in these pillows. The materials have the characteristic of being able to return to their normal shape and smooth out themselves from indentations left by your head. It’s as if they were never slept on!

    However, there are a lot of speculations about the danger these pillows pose to human health. Although they are labeled to be hypoallergenic, a number of people have been claiming to have gotten sick since they have acquired of these pillows.

    Latex pillows are made of rubber foam produced by sap from rubber trees. They are resistant to dust mites and mildew by nature. However, synthetic latex can outgas chemicals that may affect the human health. These pillows are of materials formulated from petroleum products.

    Because of the strong smell it emits, there were some users who complained of dizziness, nausea, headache, migraine and difficulty breathing. The smell however was reported to have subsided after a month or so. There weren’t much complaint filed as monitored by FDA.

    There are pillows out in the market that are made of natural latex and claim to be so 100%. They are processed naturally, washed off of proteins that might attract dust mites and free of chemicals. However, the glue used for layering could provoke allergies among sensitive users. It is safe to warn individuals allergic to latex to avoid using latex pillows.

    Memory foam pillows are made of NASA invented polyurethane from petroleum products. This synthetic material generates toxic waste by-products. The fact that it isn’t biodegradable should ring alarms. These pillows outgas volatile organic compounds that are toxic to human health. Although the smell dissipates, the toxic chemicals may penetrate your immune system. That is why hypersensitive people easily get sick from breathing organophosphate chemicals that are not easily detectable. Aside from reported dizziness, migraine, headache and asthma attack, there were also incidence of heart attack and other autoimmune disorders.

    Despite a few negative feedbacks, there are a number of people who are very happy with their latex and memory pillows. A lot has found their perfect match with them and has claimed to have provided the perfect solution for their sleep disorders.

    Although there were no clinical studies published nor publicized complaints, it is always better to be safe than sorry. There’s no harm in trying. Purchase these pillows with warranty or with money back guarantee so you would be able to judge for yourself.

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    Source by Greg J Dawson

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  • Caribbean Medical School: Fastest Way to Be a Doctor?

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    Caribbean medical schools have long been the butt of jokes but their graduates are the ones having the last laugh. There are thousands of licensed physicians from Caribbean schools practicing all across the country. Over 25% of all doctors in the US are from international schools. Do you know where your primary care physician went to medical school? This is the field where Caribbean graduates are expected to dominate with a large percentage of graduates training in Internal and Family Medicine. They are expected to fill a nationwide shortage that is currently occupied by Physicians Assistants and Nurse Practitioners.

    Picture this. A 17 year old high school graduate enrolls in a pre-medical program at a Caribbean university. Schools will automatically accept students to their medical programs as long as they maintain a certain GPA in the pre-program. This means there is no need to take the MCAT so you can save yourself the headaches from preparing for that. The program is completed in 2 years and the student enrolls in the first year of the medical degree program at 19 years old.

    Numerous Caribbean schools offer an accelerated curriculum that divide the year into trimesters. Students attend school year round and are able to complete their M.D. in less than 36 months. Not to mention you only spend 18 months studying on the island. The clinical years are spent training alongside American medical student at hospitals in the US. St. George’s medical school has hospital affiliations that match any US school. Our fictional student graduates with his Doctorate in Medicine at the ripe age of 22 (going on 23).

    Our new graduate is eligible to practice in any state in the country as long as he attended one of the “Big 4” Caribbean medical schools (St. George’s University, Saba University, Ross University and American University of the Caribbean). Internal Medicine residencies last 3 years so we have a residency trained physician ready for board exams, licenses and employment at a mere 25 years old. Not quite Doogie Howser but it’s impressive to say the least.

    This accelerated path also benefits those seeking a new career or chasing their dream of being a doctor. Time is of the essence and wasting summers off in the traditional semester system is not time well spent. Caribbean medical schools are littered with nurses, pharmacists, dentists, chiropractors and many other health care practitioners. Many schools offer several different entrance times during the year giving flexibility for students who want to begin their medical education immediately.

    There is risk involved in attending a medical school overseas but there have been thousands who have blazed the trail before you and set the precedent. Caribbean medical schools produce capable physicians and fill an integral need in the health care system of the US.

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    Source by Greg Andrew Park

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  • Debt Cure$ – Book Review

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    By: Kevin Trudeau (2008)

    ISBN 978-0-9798258-1-1

    Book Price: $25.95

    Exposing the greatest rip off

    Kevin Trudeau is one of the leading consumer advocates in America today. His mission is to expose the greed that has taken over corporate America. Kevin is a bestselling author who has sold over 15 Million books. He is blowing the lid off the banking and credit card industry, and exposing the greatest rip off in USA’s history!

    Eliminate debt

    Kevin Trudeau presents 26 chapters helping readers to eliminate debt. He discusses, negotiation (Ch. 5), reducing interest rates (Ch. 6), turning from bankruptcy (Ch. 15), stopping debt collectors from harassing you (Ch. 20), achieving wealth (Ch. 21), rebuilding credit (Ch. 22), free money (Ch. 24), more free money (Ch. 24.5), & more!

    Reducing debt’s hold

    Kevin Trudeau is clinical, precise and personable in this revealing book. He presents, “The practices of the industry are designed to make sure you are late on your monthly payments, to make sure you go over the limit on your credit cards, and to make sure that the enormous fees and incredibly high interest rates continue to go up and up.”

    Mr. Trudeau points to cultural keys for debt in society, declaring, “People turn to their credit cards when they are in crisis mode, to simply help them get by… We are a convenience-oriented society, and credit cards are convenient.”

    Kevin releases simple, practical steps for reeling in debt. He explains, “The absolute worse thing for you to do about your debt is to do nothing… You need to know your current situation in order to move forward… a balance sheet is a financial snapshot that shows your current financial health… what you made and what you spent… “

    Encouraging words release motivation for readers. Trudeau states, “When you take control of your financial health, every area of your life improves. You can sleep better… you feel less stressed… not so tense… “

    Concise data reveals powerful solutions. Kevin expresses, “Even as little as $15 every two weeks applied to your mortgage can cut one and a half years off!” And “The banks and the lenders do not want us to know that we can reduce our payments, reduce our interest, and reduce the life of the loan.” All of this information is available here.

    Breaking free from the financial industry

    Kevin Trudeau successfully provides a powerful tool for helping readers break free from the financial industry.

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    Source by Dr. Steven J. Lynne

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  • A Cardiologist Could Save Your Life

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    Everyone has to see a doctor at some point in their lives. Unfortunately there is not one doctor that can diagnose or treat every problem. If you are having any issues or concerns with chest pains, high blood pressure, shortness of breath or issues with your blood vessels your doctor will most likely refer you to a specialist that deals specifically with these types of issues. This specialist is known as a cardiologist and they deal with preventing, diagnosing and treating diseases of the heart and blood vessels.

    When you are referred to a cardiologist you can be sure that you are seeing a doctor who is highly trained in a very specific area. These doctors have an extensive educational background which includes four years of medical school and three years of training in general internal medicine. Following that they will spend another three years or more in specialized training. In order for these doctors to become certified they must have completed a minimum of ten years clinical and educational training and then pass a two-day exam that is administered by the American Board of Internal Medicine.

    There are a variety of reasons that your doctor might refer you to a cardiologist. If there is any suspicion that you might have a significant heart or related condition you are a good candidate for a referral. Some patients that have heart murmurs or any signs of change in their ECG will also be good candidates for a referral. These doctors will be involved in the treatment of any heart attack, heart rhythm disturbances or heart failure. They are also very involved in helping patients who are affected by heart disease return to a normal life and they counsel patients about the risks as well as the prevention of heart disease.

    Every patient has a different experience with a cardiologist. All patients will be required to undergo an initial consultation where the doctor will review their medical history and perform a physical examination. This examination may be a little more in-depth than what patients are used to and may include such things as having their blood pressure, weight, heart, lungs and blood vessels checked. Depending on the patient’s symptoms and the doctor’s findings on the examination a diagnosis may be made at that point. In some cases additional testing such as an ECG, x-ray or blood test may be required in order to make a definitive diagnosis. Pending the results and diagnosis the doctor may recommend medication or some lifestyle changes.

    For some people the thought of going to a doctor is scary at any age. The thought of being referred to a specialist may be even more frightening for some people. It is important to remember that your doctor would not make a referral to a specialist unless they truly thought it was necessary. It is always better to be cautious and if there are any concerns about issues pertaining to the heart you definitely want to be in the hands of an experienced cardiologist.

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    Source by Aloysius Aucoin

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