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Tag: Cancer

  • Breast Cancer The Cure

    Breast Cancer The Cure

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    You have my permission to publish this article electronically or in print, free of charge, as long as the bylines are included. A courtesy copy of your publication would be appreciated.

    Breast Cancer The Cure

    There is no known cure for breast cancer. More than 1.5 million people will be diagnosed with breast cancer this year worldwide. Scientists don’t know why most women get breast cancer, yet breast cancer is the most frequent tumor found in women the world over. A woman who dies of breast cancer is robbed of an average of nearly 20 years of her life. Breast cancer knows no social boundaries. It’s a disease that can affect anyone. Some prominent women who’s lives that have been touched by breast cancer include Jill Eikenberry actress age 52; Peggy Fleming age 49 figure skater; Kate Jackson age 50 (Charlies Angels); Olivia Newton-John age 50 actress singer; Nancy Reagan age 77 former first lady; Melissa Etheridge age 43 singer; and the beautiful Suzanne Summers actress. These high rates of breast cancer are not acceptable to the women of the world and must be met with scientific research that provides results.

    Despite over a decade of research, and more than $1.7 billion spent, hundereds of women worldwide are dying from breast cancer every day. Yet doctors don’t know how breast cancer starts or how to cure it. Doctors are still approaching treatment for breast cancer in the same old fashioned ways: surgery, radiation, and chemotherapy. Barbarick treatments…And scientists keep doing the same old redundant research that’s simply not working. It doesn’t have to be that way. Gen Cells Cures is a scientific biotechnology company that is focused on a cure for breast cancer. The company is dedicated to curing breast cancer before it’s too late for you. We’re not interested in a cure in five, ten, or twenty years from now. We want your cure for breast cancer within a year or two. We don’t want you to have to under go surgery, radiation, chemotherapy or take toxic drugs.

    Why Gen Cells Cures? You can search the medical journals; you can search the internet until your blue in the face. You will find the same old news which is no new news about breast cancer research and treatments. Breast cancer research is locked up in a black whole. Gen Cells Cures is approaching the cure for breast cancer from different angles and using tomorrow’s scientific technologies today. Our expertise is in stem cell research and genomics. Malfunctioning stem cells have already been linked to the development of breast cancer. We’re not talking about using generic stem cells from an egg and sperm cell. There is no genetic match for you with the politically controversial generic stem cells that are always in the news. The isolation of cancer stem cells, coupled with our understanding of genetic mutations causing cancer, and our knowledge of genomics will result in ways to eliminate cancer cells while sparing normal breast tissues.

    Genetics and Breast Cancer

    People will tell you to accept what you can’t change…Your genetics, your genes, the genes your mother and father handed you when you were born that came with their particular genetic make-up. Most inherited cases of breast cancer have been associated with two genes: BRCA1 and BRCA2. The past five years has been a period of unparalleled discovery in the field of genetics, genomics, and stem cell research, but these discoveries are not being applied to breast cancer treatments. A job that Gen Cells Cures definitely wants to get our hands dirty in. Recently researchers have found that by blocking a gene called beta1-integrin the growth of tumor cells can be stopped. When this gene was removed the tumor cells quit growing. You don’t have to accept the genes that you were given at birth. Gen Cells Cures will be able to manipulate your genes to cure your breast cancer.

    Our Cancer Stem Cell and Genomics Program will bring together the top scientific minds in the world under one tin roof to maximize the use of diverse approaches to the understanding of cancer genomics fused with stem cell solutions. Gen Cells Cures isn’t looking for a multi-million dollar biomedical research center like the Stowers Institute in Kansas City, which is a medical center to be admired. A rented tin shack will do just fine. Of course, we would accept hand-me down michroscopes from the Stoweres (billionaires who bought their own multi-million dollar biomedical research center) if they would be gracious enough to grant them to us or we would accept a small prime the pump check to move forward with our research. The Stowerses and all the scientists from the Stowers Institute have an open invitation to visit our lab in the Caribbean. What we are looking for is a cure for breast cancer to stop the humiliation, pain and suffering this menace to society causes millions of women and thousands of men worldwide, and not a new biomedical center… Every dollar invested with us goes into pure medical research and equipment. The same offer goes out to all the millionaires and especially the billionaires of the world. People that come to mind are: Paul Allen, Bill and Melinda Gates, Jon Huntsman, William and Alice Goodman, Ann Lurie, Jamie and Karen Moyer, Harold C. Simmons, Alfred Mann, Sumner M. Redstone, Michael Milton and the Palm beach billionaires, there are simply too many to mention. The combined wealth of the three Microsoft billionaires alone is more than ten times the amount spent by the U.S. Federal Government on research to fight cancer and other deadly diseases. We know we’re in the wrong business to become billionaires ourselves. This kind of biotechnology has never produced even one billionaire. It’s the cure for breast cancer that we want.

    Simply put the cancer research organizations are funding the wrong researchers. It’s time to go outside the normal research channels. Do something different. The same story year after year after year and no cure. These unmotivated researchers just aren’t getting results. Let someone else have a shot at it. It’s time to try something new and different. A different approach. There are races for the cure, golf tournaments for the cure, there are walks for the cure, there are foundations for the cure. These foundations have been funding the same ineffective research for more than twenty years now. These foundations have been betting on the wrong horse. Joining the crusade won’t help if the research being done doesn’t take on a twenty-first century scientific approach. It’s been time to move forward scientifically for five years now. But today’s breast cancer researchers are stuck in a twentieth century mind-set. The Excuse is someday we’ll find the cure, but someday doesn’t help today’s victims of breast cancer. We need top notch scientific action today.

    The genetics are out of the bottle and stem cell research is moving forward whether the U.S. government likes it or not. Gen Cells Cures has moved off-shore to the Caribbean to avoid the political controversy over stem cell research. I am sure you won’t mind a walk on the beach with me to talk about your cure for your breast cancer. Once we have the cure we can take the cure from the bench to the patient without a long and costly wait for FDA approval. There are many advantages to not having big brother breathing down your neck. The governments of the United States and Western countries have nothing to offer except road blocks, red tape and detours. Our patients don’t have time for political smoke and mirrors. With a little luck we could have your cure before the time comes that you need that dreaded surgery and chemo.

    Our gifted world-class researchers are visionary and have been schooled in winning and have courage, creativity, can-do attitudes, burning desires, unfaltering belief and an obsession that they will be there first. By first we mean years ahead of the other biotechnology companies. Like determined, fighting NASCAR drivers our scientists are living to take the chequered flag of biotech and win the coveted race for the cure for breast cancer.

    Focused on breakthrough discoveries, Gen Cells Cures nurtures a culture that encourages high standards of excellence, original thinking, hard work and a willingness to take risks. Our world-renowned scientists believe in themselves and its belief that gets us there. The company will seek to develop a work environment that is results focused and team-orientated. We compete against time. Though we compete intensely we maintain high ethical standards and trust and respect for each other. Quality is the cornerstone of all our activities. We seek the highest quality information, decisions and people. Our success depends on superior scientific innovation. We see the scientific method as a multi-step process which includes designing the right experiment, collecting and analyzing data and rational decision making. It is not subjective or emotional but rather a logical, open and rational process.

    Our success comes from one simple fact; we are committed to being a science-based, patient-driven company, driven by that one special breast cancer patient…you.

    Gen Cells Cures lost most of our one million dollar start-up money in offshore bank scandal and currency devaluation last year. We are now actively pursuing financial support. Unfortunately, the Gen Cells Cures team is made up of great scientific minds and not great marketers, salesmen, or fund raisers. Yes, we are looking for a millionaire or billionaire without a cause to support our work, but if you are not our wealthy saviour, we welcome any help, be it financial or a donation of your time. The scientific team is on stand-by. What we’re lacking is the funding to go forward. We could use motivated salesmen to sell our research, fund raisers, skilled internet marketers or someone just to pass out flyers or mail out promotional material. We could use help from the media with publicity stories, ads and promotions to get the word out. We are particularly interested in looking for assistance from the billionaires of the world; there are approximately 600 in the world. Billionaires like Sergey Brin and Larry Page (Google billionaires), Rupert Murdoch, Ted Turner, and Oprah Winfrey and others who control the media could get our life-saving message to the world fast. We are also hoping that some of my celebrities friends will come forward and spread their wings to help support our breast cancer research: Steven Seagal, Charlie Sheen, Wesley Snipes, Danny Glover, Erik Estrada, Tom Arnold, Dolph Lundgren, Roger Clinton, Bill Clinton, Usher, Hulk Hogan, Ivana Trump, John Secada, Sylvester Stalone, Arnold Schwarzenegger, Mike Reno, Richard Branson, Cindy Crawford, Cher, Demi Moore, Michelle Pfeiffer, and other stars that I have had the good fortune of meeting in person and others celebrities that I hope to meet in the future. (Photos of Gerald and the stars can be viewed at his promotional group listed below.) I am waiting to get my photo with Suzanne Summers!

    Gen Cells Cure offers more than hope. We can do the job. If you’re going to eradicate cancer you have to have the right people doing the right research. One thing is for sure. We couldn’t do any worse than what the scientists before us have done. Which is virtually nothing! Help us alleviate the pain and suffering. Together, with your help, we can cure breast cancer.

    Article by Gerald Armstrong- scientist0707@yahoo.com

    Gerald is the owner of Gen Cells Cures

    Visit his group for information about “The Cure” for incurable diseases and aging.

    Group address [http://www.msnusers.com/cures]

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    Source by Gerald Armstrong

    Views: 1

  • Family Medicine And Family Physicians

    Family Medicine And Family Physicians

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    To become a family physician, men and women go through a four-year degree program, they study in an accredited family medical medicine residency program, and an additional three years of training before becoming board certified. A family physician is your one-stop healthcare expert. They treat everyone in the family and they exam, research, and diagnose medical conditions from head to toe. This type of care is called integrated care where a family doctor devises individualized health plans to treat mom, dad, and children of all ages. Family doctors treat a wide range of health conditions and they can be your primary care physicians at any point in your life. Unlike other specialties, family medicine involves coordinating all types of healthcare issues, from a common cold, pregnancies, to treating an acute or chronic illness.

    Family physicians must practice at the highest level of medical care throughout the world. They are required to become re-certified around every six years, through American institutions like The American Board of Family Medicine, The American Academy of Family Physicians or the Accreditation Council for Graduate Medical Education, all of which have reciprocity agreements throughout the globe for family medicine training. A few of the advantages in being seen by a primary care physician, includes the following:

    • family doctors have all of your personal and family medical history because they have been treating you for years.

    • physicians that have seen generations of family members can help in researching various genetic diseases, like cancer, if it appears more than once in a generation.

    • doctors involved in family medicine environments can perform minor surgical procedures without the added cost of seeing a specialist.

    • they improve the lives of the underserved in America and abroad.

    Research and clinical studies have proven that US and worldwide primary care physicians have been responsible for lowering the world mortality rates in diseases, such as in cardiovascular diseases, cancer, diabetes, low birth weight issues, obesity, and many other illnesses and health conditions. The statistical results associated with the care provided by family physicians, have proven that they help to increase life spans and control diseases from spreading. Their participation in healthcare has reduced healthcare expenditures, they help to lower hospital admissions, emergency room admissions, and they help to reduce surgical costs.

    A family doctor focuses on preventive care, community oriented care, global health, plus they diagnose and manage a wide range of health problems to improve the quality of care in local, rural, urban, and large city health. Even if people are generally healthy, patients benefit by keeping a relationship with their primary care physicians. The physicians support individuals to stay healthy through dietary programs, they encourage their patient's to exercise to stay physically and mentally healthy.

    One of the main reasons that family medicine works, is the relationship that patients have with their doctors. This specialized and confidential relationship is great for individuals who feel comfortable in talking about their medical health with their physicians. Physicians around the world, are available to answer their patient's questions in a way that forms a trusting bond. This bond creates a trusting relationship, whereby patients will listen and follow their healthcare provider's advice and directions, thus decreasing chances of spreading contagions .

    Family medicine is all about treating the whole person, not just their symptoms. A family physician has a profound effect on the physical, mental, environmental, emotional, and spiritual health of each of their patient's. Physicians with an intimate knowledge of their patients can help introduce the healing power of hope, love, faith, and trust, as life presents challenges that can evoke depression, fear, grief, and anger. Also, if a physician's patient requires the need to see a specialist, a family doctor will help coordinate your care. Patients can often feel frustrated and confused when they have to manage the healthcare system on their own. With a family healthcare provider on your side, the whole medical care journey is made easier and less frightening of the unknown.

    Refugees have always fled to foreign countries, including the US for a chance of better opportunities for themselves and their family. The present global news events are following refugees today, who are fleeing from their native countries for various reasons. Before being accepted for resettlement, all refugees must pass medical screening examinations, which is often performed by primary care physicians. The physicians perform a thorough examination of a variety of health problems that involve the mental and social health of the refugees. The family doctor's check for infectious diseases, chronic illnesses, the refugee's overall musculoskeletal system, and parasites, thus providing immunizations. The information that they gather is shared with that country main health agency, which in the US Is the Centers for Disease Control and Prevention.

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    Source by Ryan A Buffington

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  • Oxalic Acid – The Cure For Cancer

    Oxalic Acid – The Cure For Cancer

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    Daily, certain foods and beverages are revealed as great antioxidants. For example: carrots, spinach, broccoli, tea, nuts, berries, garlic, onions, grapes, red wine, herbs, spices, and chocolate are foods known to be great antioxidants. We hear about flavonoids and vitamins. It is estimated there are 4,000 identified flavonoids. Isolating each one and determining what effect each, or a combination of each, has on a specific disease is an endless pursuit without an answer. However, common sense and research reveals there is one common denominator in the foods known as great antioxidants. They are all high in oxalic acid.

    Are you aware that every mammal on earth has oxalic acid as a normal blood value? Ask any doctor or researcher what its purpose is and the best answer they will give you is that it aides in bowel movement. So here we are with a surprisingly high quantity of oxalic acid running through our blood with no real purpose?

    There isn’t a place on earth that a plant containing oxalic acid can’t be found. Weeds are the most tenacious of all plants and are rich in oxalic acid. This is no accidental occurrence. There is purpose.

    Research oxalic acid and you’ll discover it’s a deadly poison. So, we have a deadly poison in all the foods that are great antioxidants. Huh? Stop and simply think. Rather than isolating the smallest compounds within foods and researching each, analyze each food known to be a great antioxidant and find the common compound in each. This is exactly what has been done by an amazing 85 year old warrior of a man deep in the hills of Arkansas. This man is Colonel Joe Hart.

    When is the last time you knew of anyone being granted a patent for anything natural? That folks, never happens. It has for Colonel Joe. He has been granted three (3) Patents for the Application of oxalic acid for treatment of cancer, bacterial and viral infections, and vascular diseases. Why isn’t the medical community screaming its merits? I wonder if the fear that this would eliminate a trillion dollar yearly health industry have anything to do with it? Talk about an answer to our nation’s health care crisis.

    Colonel Joe discovered the benefits of oxalic acid during 1992. Once oxalic acid was identified as the acid which kills cancer cells without harming normal cells, he was then able to identify what foods and environmental factors inhibited the therapeutic value of oxalic acid. His approach to eliminating disease by ingesting high oxalic acid foods, has resulted in cures of all kinds of cancer and disease. Do you need to pitch a tent in your backyard and live by a campfire? No. Is this going to cost a fortune? No. Do you need to travel to Mexico? No. Is the information freely given? Yes.

    There is always a sacrifice for gain. Prepare to give up milk and cheese, citric acid (an additive found in far too many processed and canned goods), red meat, cell phones, microwaves, and alcohol. If this proves too difficult, you can always go in for traditional surgery, radiation, and chemotherapy only to find that the cancer comes back eventually or you die. You do know doctor’s never tell you you’re cured……you’re in remission. “Cure” is not in their vocabulary.

    Ask your doctor the next time you or someone close to you is diagnosed with cancer what caused it. They don’t know. The answer is low levels of oxalic acid in your blood. Having adequate levels of oxalic acid in your blood eliminates all abnormal cells effectively with no harmful side effects. Oxalic acid is God’s Poison With Purpose.

    If you seriously look into every alternative cancer cure that shows some success, you will find the foods, herbs, grasses, and teas they suggest all contain high amounts of oxalic acid. They simply don’t know why their protocols sometimes work. Connect the dots people and stop throwing your money away.

    Ask the American Cancer Society about tests they conducted over 50 years ago using oxalic acid in the treatment of cancer in experimental mice. The papers and evidence of positive results exist; however, they will tell you they know nothing about it.

    Simply go to the grocery store, eat your chocolate, vegetables, fish, dark chicken, tea and wine. Toss out the microwave and cell phone. Say “No” to fast foods and truly enjoy eating your way to excellent health.

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    Source by Jennifer Prescott

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  • Heal Your Life Or Cure it – The Difference Between Healing and Curing

    Heal Your Life Or Cure it – The Difference Between Healing and Curing

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    We often hear of prayers for successful healing and other stories of people who have had miraculous cures. Recently I learned a friend who'd had tumors in several places throughout his body had learned that the tumors were gone completely. His doctors were stunned and couldn't explain it.

    While that was very good news, it also may have demonstrated the power of healing prayers. My friend had asked our group to pray for his healing and we did. But of course, we can never be sure how much our prayers contributed to the disappearance of the tumors and how much his own wonderful attitude and philosophy of life and health was responsible for the miracle.

    While we prayed, treated, meditated, for healing, what we really wanted was a cure. There is a very big difference between curing and healing, although the lines between them often are blurred. When I pray and meditate for a loved one who has a problem, whether physical, emotional, spiritual, or otherwise, I start by asking for healing.

    To me, healing means reaching a point of wholeness and peace, no matter what the physical condition or situation may be. I believe it is possible to have a terminal illness, but to be healed though the illness eventually takes the life. On the other hand, to be cured means that the illness goes away or is "fixed."

    Sometimes a person who survives something as serious as cancer, then needs time to heal, even though he or she may have been cured, like my friend was cured of his tumors. Healing will mean taking time to think about what happened and to reach conclusions about life and death and to consider the lessons learned by the experience. While a cure may be found in a short period of time, healing can take a longer time but lead to a better quality of life.

    Healing is closure, but does not mean that the lessons learned are over or that more cannot be learned. Healing leads to personal and spiritual growth. Curing means that we get to live longer and to work on healing. I sometimes think that we spend a lifetime healing.

    While curing comes from an outside source, such as a wonder drug, healing always comes from the same source, from within. When a loved one is sick or dying, first we want a cure, so that we do not lose that one, but ultimately, we realize that death is inevitable and what we really all need in the end, is healing. From a place of wholeness we can face all of life's challenges.

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    Source by Wil Langford

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  • Importance of Evidence-Based Complementary Medicine

    Importance of Evidence-Based Complementary Medicine

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    The modern-day world has many challenges and thus good health is one of the greatest blessings in today’s era. For example, a rich man with a bad health will always be unsatisfied and unhappy! “Health is Wealth”. Improving your health is an opportunity that shouldn’t be missed. It is a fact that your health affects all the aspects of your life, be it professional, or personal. Probably that is the reason why evidence-based complementary and alternative medicine came into existence!

    With increasing number of health-related apps and journals on the internet, you can now easily move towards a healthier lifestyle. Even the experts of medicine have admitted that the advice and products of work best when supplemented with a doctor’s standard care and supervision.

    As the famous proverb suggests, “Prevention is better than cure” and evidence-based complementary and alternative medicine helps you achieve this goal. So, here are a few benefits that you might get if you follow an integrative healthcare protocol:

    • It helps you in receiving specific treatment plans as per your physical requirements. As each individual has a unique body, it is not advisable to subscribe to a generalized treatment protocol. An effective biotyping assessment studies your inherited traits such as body frame, personality type, digestive capacity, metabolic activity, nutrigenomics, as well as environmental factors. In this way, it provides you with a personalized holistic Integrative healthcare medicine advice.
    • It aims at examining and treating all the aspects of physical as well as emotional components. It is proven that daily stress negatively affects your emotions, biology and genetics. All this further results in greater risks of several chronic diseases such as cancer and heart disease!
    • It offers a wide range of Natural Cure and Remedies so that you are not completely dependent on pharmaceuticals, many of which have side-effects. The food that you eat is one of the biggest reasons behind your healthy (or unhealthy) life! Following unhealthy food habits can result in an increase in the risk of heart conditions, high blood sugar, obesity, etc. So, what could be better than utilizing food as a medicine?
    • It focuses on the prevention of diseases before it even occurs. While conventional medicines are prescribed for a lifetime for chronic disease, alternative medicine examines the root causes of the disease. It also encourages the patients to focus on preventing a disease by eating healthy foods, exercise, meditation, etc.

    So, if you also wish to treat or prevent any disease with Natural Cure and Remedies, evidence-based complementary medicine is the key! After all, it’s never too late for improving your health.

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    Source by Luke Harper

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  • Cure Your Acne By Adopting a Vegan Diet

    Cure Your Acne By Adopting a Vegan Diet

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    If you are reading this article you are getting closer to finding the causes of your acne. I am glad that you might want to try to cure your acne by adopting a vegan diet.

    I tell you that simply going vegan might not be the entire answer you are looking for. The reason that I tell you this is because the term "Vegan" is a very general term that simply means that the food is free from animal products.

    Adopting a vegan diet that only consist of non toxic, non allergenic, and good for your specific genetics will definitely help to cure your acne. The thing is, is that there are many acne causing foods and ingredients that are vegan.

    To give you an example of things that are considered vegan, but that will cause your acne to get even worse will include, Table salt. hydrogenated oil. food additives, food colorings, and anything that your body is allergic to.

    Also one of the foods that makes me break out with acne is any kind of wheat product. Wheat gluten is known to cause many health problems. Wheat gluten is kind of like glue that holds things together in many vegan products in the store.

    Many vegan foods that resemble meat actually contain lots of wheat gluten. Also a very popular food chain that brags about being vegan and vegetarian and the name has something to do with veggies and being grilled or something (I am being vague about using their exact name as I don't want to directly bash them), they use a lot of gluten.

    So while myself and others have in the past adopted a vegan diet to try and cure acne have had success on a vegan diet. It was however a very specific vegan diet.

    White sugar is vegan, also wheat gluten. MSG and its many names (you might want to research all of the names of MSG) is also vegan but is not good for you at all. So people throw the Vegan word around thinking that it is a magical characteristic of a diet that healthy.

    This is where many vegans that are unhealthy go wrong. They are eating tons of vegan foods that are clogging them and making them sick. Bread can be very constipating and it contains wheat. Most people have a food allergy to wheat even if they don't make the connection between the bread they eat and their symptoms.

    I am almost positive that if you are reading this right now you are probably very frustrated with all the conflicting information on the web. The big food corporations pay "ghost writers" to write nonsense to promote the foods they are selling even if they know what they are selling might not be good for you.

    To avoid becoming brainwashed by the media, and to avoid what they are selling, why don't you make yourself a challenge. I challenge you to prepare almost all of the food and know what each and every ingredient that goes into your body is and what it is made of.

    I challenge you to write down every last thing that goes into your body. It isn't as hard as it seems if you try to eat whole foods. Eat tons of Romaine lettuce, carrots, almonds and other raw nuts (no peanuts) extra virgin olive oil. sea ​​salt, raw hone, olives, and other fruits and vegetables for a few weeks.

    This means no fast food. You see French fries are vegan. In my opinion looking at the acne and food connection is that they are very unhealthy and probably cause me to break out in acne. The reason is that french fries are deep fried in oil and the oil is damaged by heat. Also the oil is probably made from GMO ingredients. This topic is too broad to explain why it is not good for you.

    In short your body might perceive the oil as an allergen. Also the fries are also probably covered with table salt. Table salt is not good for acne.

    Also there is a very popular fast food chain (which is probably the most well known for giving away free toys in the meals of the kids and brainwashes the youth and makes them sick at such a young age that they never know health and what it feels like their entire life) that clearly admits that their french fries contain things that can cause cancer. I am not kidding you. We need to read the warning on the fries.

    Anyway, I don't want to get sidetracked, To help you to cure your acne and to be truthful, I want to let you know that adopting a vegan diet to cure acne is a good idea to try. It's just that you need to be very selective in designing your vegan diet.

    Simply being labeled "Vegan" does not make it healthy.

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    Source by Teddy Grandy

    Views: 0

  • Journey of a Drug: Design to Market Seller

    Journey of a Drug: Design to Market Seller

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    Where do the medicines we take from chemists come from? How do the doctors know which drug is good for which disease? How the medicines really are able to cure a particular ailment they have been prescribed for? Do these questions come to your mind, whenever you buy any medicine?

    Come, let us today know about the medicine development from the beginning …

    The development of medicine is called a Clinical Research and has different Phases. Phases of the clinical research are the steps of experiments with a health intervention in an attempt to find enough evidence for a process which the scientists think would be helpful in medical treatment.

    The pharmaceutical study starts its journey from a drug design and drug molecule discovery which further progresses into animal testing and then human studies to see the drug's effectiveness.

    Drug undergoes many trials- Preclinical, Phase 0, Phase I, II, III and IV. Sometimes combined trials also are undertaken to reduce the time of development, like Phase I / II and II / III.

    Pre-Clinical Study

    When the drug molecule is identified, it undergoes many in vitro ( test tube or cell culture ) and in vivo ( animal ) experiments. These experiments are conducted to know the preliminary efficacy, toxicity, and pharmacokinetics of the various doses of the drug. Many drug molecules are designed at a time and these pre-clinical studies let the pharmaceutical companies decide which molecule has a greater potential in further studies.

    Design of the Studies:

    Trials are always conducted by following the set of steps, called the protocol, developed by the researchers to find the specific questions related to the medical product. Information from the prior studies become the base for the researchers to develop research questionnaire and objectives:

    • Participant selection
    • Number of participants
    • Duration of the study
    • Controlled or not
    • How and what dosage will be given
    • What and when the data will be collected
    • Review and analysis time

    Phase 0 Study

    It is also called micro-dosing trials, 10-15 human subjects are taken and single sub-therapeutic doses are administered to gather the pharmacokinetic ( PK ) data of the drug. This enables the company in deciding to go or no go for the further development of the drug, based on more relevant human data instead of animal data.

    Such trials exceed the speed of promising drug development by establishing whether or not the drug acts on humans as expected in pre-clinical studies.

    After the company decides to take the molecule of the drug forward in development, it will have to submit the data of its preliminary studies to the FDA called Investigational New Drug ( IND ) application filing.

    Phase I Study

    Also called First-in-man studies as these are the first stage of human testing studies. These are the studies which are designed to determine the maximum dose that can be administered without showing adverse effects.

    Contract Research Organizations ( CROs ) conduct such studies in the clinical trial clinics where medical staff provides full-time attention to 2-100 healthy subjects enrolled for the study and collects the data.

    These studies determine the safety ( pharmacovigilance ), tolerability, pharmacokinetics ( PK ) and pharmacodynamics ( PD ) of the drug. The design of Phase I studies is dose-ranging also called dose escalation studies conducted in controlled clinics called Central Pharmacological Units ( CPUs ).

    Usually, healthy subjects are hired but sometimes terminally ill patients like of cancer and HIV and also those who have already tried and failed to improve on existing medications.

    There are two divisions for Phase I study:

    Phase Ia: Single ascending dose

    Phase Ib: Multiple ascending dose

    Phase II Study

    More than 100 diseased subjects are enrolled for a longer period study, to know the benefits of the drug along with its safety which includes genetic testing. These studies are also called as "Proof of Concept or Pilot" studies.

    This is the phase when the drug's development can fail due to toxicity or less than expected results.

    Two divisions of this phase are:

    Phase IIa: Pilot study, to determine the clinical efficacy or the biological activity.

    Phase IIb: Dose-finding study, to check the biological activity with minimal side-effects.

    A combined trial determining the efficacy as well as toxicity are Phase I / II trials.

    Phase III Study

    These are pre-registration trials means the data of this study is submitted to the regulatory agency through New Drug Application (NDA) for its registration. Also called Pre-marketing or Pivotal trials.

    Such studies are multicentral, randomized, in large diseased population ( more than 500 ) with much longer duration of treatment and short follow up period, to determine the long-term safety and efficacy of the drug.

    Even if the regulatory submission is pending, the drug is received by the patients in case it's a lifesaving drug until the drug can be purchased.

    'Label expansion' that is drug can treat an additional disease, other than the disease for which the drug is already approved, may also be the reason for running the Phase III trial.

    It is said that for FDA ( United States Food and Drug Administration ) and MHRA ( United Kingdom's Medicines and Health products Regulatory Agency ) needs at least two trials of successful trials data to register the drug.

    After these trials, the drug is approved for market selling.

    Phase IV Study

    These are Post Market Safety Monitoring studies done after the drug is registered. Also called Late Phase or Confirmatory trials.

    This kind of study determines the long-term adverse effects on the much larger population for a very long duration (at least 2 years). If harmful effects are detected in this study, then the drug is disapproved and the company has to retrieve the drug from the market as it can no longer be sold.

    The entire journey of the drug from a molecule to a market selling product takes around 15-20 years.

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    Source by Nidhi Sharma

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  • The Unique Power of Ayurveda to Heal Any Health Problem

    The Unique Power of Ayurveda to Heal Any Health Problem

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    The amazing power of Ayurveda

    What comes to our mind if we think about any types of treatment? It will obviously be allopathy or homeopathy. No wonder that Ayurveda secures no position in the list of the trustworthiness in the mind of many people. This Ayurveda has some kind of power which will go deep inside or in the root to eradicate any disease. This medication, from ancient time, is somehow overlooked or ignored by the users. The Ayurvedic Medicines exist or not we rarely bother! Things will get changed once you start believing it.

    Ayurveda works if someone trusts

    The young generation has a tendency to give a stare to these age-old medicines. They consider this type of medicine belongs to the pre-historic era. Ayurvedic treatment needs patience as well as time. All those who are in a hurry; this type of medicines will not be good for them. You can rely on Ayurveda if you enough time to use it regularly, without making any kind of mistakes. These Ayurvedic Medicines have no side effect. Yes, because of the main ingredients of this medicineor herbs. Taste-wise it will not be great of course. There are so many people who all have shown their faith in Ayurveda and got the desired result. You can be one of them easily. The biggest benefit of this Ayurveda is that it is not costly. Any and every kind of health related problems can easily be resolved by the touch of Ayurveda.

    Why should you switch over to Ayurveda?

    • A non-curable disease like Cancer and all can be cured by the power of herbs.
    • Those who all are afraid of operations, this will be the greatest option for them. Ayurveda believes that surgery is the last step.
    • Chronic diseases can easily get cured by Ayurveda medicines.
    • These medicines are free from chemicals. That means no worry of side effects at all.
    • Consumption of these types of medicines will cure the problem as well as develop the overall health condition by increasing the rate of metabolism, decrease the level of stress and bring back the obstinacy back into your life.
    • These types of medicines will go to the root to eradicate the problem. That means that particular person will not suffer from the same problem again.

    Availability of these Ayurveda medicines

    Ayurvedic Medicines Manufacturers and dealers must be there in your locality also. Why don’t you visit one of those medicine shops and read out the compositions of these medicines by yourself to kick away all misconception regarding Ayurveda and its result? At that time only you will start believing in the magic of Ayurveda.

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    Source by Samaria Thomas

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  • Everything You Ever Wanted To Know About a Pain Doctor

    Everything You Ever Wanted To Know About a Pain Doctor

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    In all likeliness, you must have heard of the term ‘pain doctor’, otherwise also known as a pain specialist or even as a pain management specialist. Pain doctors help in managing pain and focus on pain medicine, which is all about preventing and treating different kinds of pain. Here are some of the things you need to know.

    What Are the Qualifications of a Pain Doctor?

    A pain doctor can be a medical doctor, also known as MD, or can be a doctor of osteopathy, specializing in pain medicine. Apart from treating pain-related disorders, they also treat symptoms that may have triggered pain. They also work with patients who have to deal with pain owing to a particular condition, such as post-operation related pain. In terms of services, many torment doctors have their clinics, where they offer comprehensive care for most pain-related conditions, or else, they may also work as consultants to healthcare providers and doctors. The role of pain doctors is an extensive one, where they offer counseling to patients, perform procedures as required, prescribe medicines and even offer emotional support. In a number of cases, where is caused due to a certain condition or diseases, the physician may refer the case to a pain management specialist, while keeping a check on the primary treatment. Apart from a medical degree, which is an obvious must, physicians are required to have a state license in the US.

    What Are the Areas of Specialization?

    torment management doctors can treat most conditions, not limited to back and neck torment, chronic torment, cancer torment, arthritis, reflex sympathetic dystrophy, pelvic torment, headaches, fibromyalgia, and orofacial torment. Many torment doctors are a part of different organizations, such as the American torment Society.

    How Are Patients Treated?

    Patients experience pain owing to a number of reasons, and therefore, the diagnosis and treatment also differs. Doctor usually suggest tests before starting off and may consider the family history of the patient, along with other relevant factors such as lifestyle and diet habits. Also, a detailed physical examination will be done to understand the pain conditions better. As for the treatments, the approach determines the next step. Some treatments are planned in a way that patients can live better, despite the pain, while others are more focused on reducing the extent of pain.

    Common Treatments:

    Pain doctors may use different kinds of treatments, such as injections in form of corticosteroids, and medications. Along with that, implantable devices such as stimulators are also used, besides physical therapy, surgery and trigger point injections. Lifestyle changes, meditation, hypnosis and relaxation are some of the other things that doctors may use to help a patient.

    If you are suffering from chronic pain, consider seeing a pain doctor or ask your primary healthcare physician to offer help. The idea is to start treatment early, which may help in dealing with the symptoms better, and yes, do follow your doctor’s instructions for movements, actions and other things, especially if certain lifestyle changes can reduce your pain considerably.

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    Source by Hampry Gomes

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  • HOLISTIC Approach To Medicine

    HOLISTIC Approach To Medicine

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    Most people seek better health, but, often, their fear of going to the doctor, or needles, or taking certain medicines, and / or, their desire to avoid what they might consider the risks / side effects, associated with some convention treatments, become a risk to their personal health, and well – being. In the United States, our system of medical treatment is often referred to, as allopathic , which focuses on treating diseases, as opposed to preventive medicine. In many / most of the rest of the world, the emphasis is on reducing illnesses, by enhancing / improving our resistance, and / or immunity, and avoiding taking chemical medicines, initially, but only, when other approaches, aren't indicated. With that in mind, this article will attempt to briefly, consider, review, examine, and discuss, the HOLISTIC alternative / approach, using the mnemonic method.

    1. Healing; homeopathy; heart / head: Holistic practitioners, often focus on healing the entire / whole person, including balancing the emotional and logical considerations, in a head / heart balance, without resorting, first, to merely treating symptoms. Most nations use homeopathic medicine, in a thorough, wellness program, as well as many other modalities.

    2. Options: The focus is on taking advantage of all, viable options and alternatives, used together, towards creating better health!

    3. Listen; learn: Wellness medicine treatment takes the time, to ask lots of questions, and listen carefully, in order to learn more, and be best positioned, to better health!

    4. Importance; ideology; ideas; investigate: Utmost importance, in an alternative regimen, is possessing an ideology, of considering the bigger – picture, and take advantage of the finest relevant ideas / alternatives. When one investigates the options, and alternatives, he places himself, in the best position, for a potentially, healthier life, etc.

    5. Systems; stronger; sustain: When one focuses on the best way to sustain our existence, and proceed, in a stronger way, he accepts alternative systems, focused on a healthier lifestyle!

    6. Timely; trends: Pay attention to the discoveries, trends, and new alternative techniques, with the focus, on the best. most relevant alternatives, might create a healthier – you! In every medically – related, instance, it's essential to pursue, well – considered, timely actions and treatments, while ruling out major illnesses, such as cancer, etc.

    7. Imagination; insist; improve: If you hope to improve your health, you will have to work, on it, while maintaining the imagination, to consider options and alternatives, and insist, on doing everything, possible, to enhance your well – being.

    8. Care; caring; coordinate: Coordinate your care, and know, when allopathic approaches are needed, and necessary, and when, holistic approaches and techniques, might be best, for you! Happy people are generally, best – positioned, to be healthier, and are often, the most caring individuals.

    Wise people don't ignore the possibilities, and are ready, willing and able, to consider, when HOLISTIC medicine and techniques, are best – suited, for you. Will you maintain the open – mind, to be the healthiest, you might possibly, become.

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    Source by Richard Brody

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