Tag: AFFECTS

  • Nose Injuries – When There Is No Doctor

    Nose Injuries – When There Is No Doctor

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    Injuries to the nose are not uncommon; yet, when they happen, people tend to panic. Instead of letting the situations "lead you by the nose", follow these simple first-aid measures, and stay in control:

    Your nose is not merely an organ of smell. It's a filter, a temperature controller, a passageway and sometimes even an alarm system. It is closely connected with your eyes, mouth, ears and head, both cosmetically and physically. So, when it is injured, to treat it you've got to look beyond your nose.

    "In order to treat any injury to the nose, you must first understand the nature and extent of the injury," say ENT surgeons. "Basically, there are three kinds of injuries: those that involve the nose and the head; those that affect the nose and the face; those that pertain only to the nose. Only after the kind of injury has been ascertained can proper treatment or first aid follow. "

    The first two kinds of injuries are usually the result of a violent, perilous impact, like a fall from a great height, or a road accident. When the nose and the head are injured – and such cases are obvious even to a layman – the damage is serious and can occasionally be fatal. In all probability the victim will be unconscious and to render first aid would be impossible. Your only course of action is to rush the victim to a hospital and leave him in the hands of the doctors.

    If the head is not hurt, that is, if the injury is only to the front of the face, then check the extent of the damage. Any injury to the eye directly, or even to the area around the eye, will need a doctor's attention. You can try to control the bleeding of the nose, if there is any, but the person should be taken quickly to the hospital. Probably he will need the attention of the ENT surgeon and the ophthalmologist.

    Injury to the nose and to the area around it, that is, the sides and below, could mean damage to the sinuses and upper jaw. Ask the victim to make as if he is biting on something. Difficulty and pain in moving his mouth indicate probable fracture of the upper jaw. In this case, too, though you could try to control the bleeding from the nose, the victim needs medical attention. An ENT surgeon and a dental surgeon may have to work together to repair the damage. Therefore, such a case should be quickly taken to the hospital.

    The third type of injury is more commonplace. In this kind of injury, first aid can be given, but again, it will depend upon the cause and nature of the injury. Injuries to the nose can be broadly grouped as: external wounds; fractures; obstruction by foreign objects; bleeding from the nostrils.

    EXTERNAL INJURIES

    External injuries like abrasions, bruises, cuts and punctures can be treated as you do wounds. Clean the affected area, apply an antiseptic and bandage. Slight abrasions or cuts will heal with adequate care. Deep and extensive wounds should be shown to a doctor.

    Fractures of the nose are easily detectable from the distorted shape of the nose, the constant pain and swelling. Fractures have to be splinted and set right, which can only be done by an ENT specialist.

    Those with children will b familiar with the third type of nasal injury – that is, blockage of the passage due to insertion of foreign objects into the nose. "" Often, the child may not be aware that he has done something he shouldn't have, says ENT surgeon. "" So the object remains in the nose for days and is discovered only when infection sets in. then, either the parents notice that the child's nose is swelling, or the child complains of pain in the nose. "

    However, even if you know that the child has pushed something up his nose, don't try to extricate it yourself. You could push it in even further. Sometimes, lightly blowing the nose helps to dislodge the object. But if the object is edged, it may scrape or bruise the nose and bleeding may result. So it's safest to take the child to a doctor, preferably an ENT specialist, as he is better equipped to deal with the problem.

    NOSE BLEEDS

    Nosebleeds or epistaxis can occur due to a number of reasons: Sudden climatic changes; a rise in blood pressure; a traumatic injury; high fever.

    The air we breathe in has to be homogenised to the body temperature of 34 ° C before it reaches the lungs. The nose acts as a temperature controller. If the air is cold, the nose warms it; if the air is too warm, the nose cools it. In order to help it carry out its function, the nose is heavily lined with blood vessels. The supply of blood depends upon the difference in the body and atmospheric temperatures. When the temperature outside changes suddenly, as when we move from a warm climate to a cold place, or vice versa, the demands on the blood vessels can be extensive and, consequently, they are likely to rupture, resulting in a nosebleed.

    A rise in blood pressure forces the blood vessels to enlarge and sometimes even burst. Since the capillaries in the nose are fine, they rupture more easily. Thus a nosebleed could be a symptom of hypertension. Also, during plane flights, if cabin depressurisation takes place, the difference in air pressure outside the body and within affects the blood vessels and some passengers could experience bleeding from the nose.

    Any trauma inflicted on the nose – say, when you fall while running and hit your nose on the ground, or when a child is hit on the nose by a ball while playing – ruptures the blood vessels inside the nose. Often, in these cases, the bleeding may seem heavy, but if there is no fracture, it may not be grave. However, once you've stopped the bleeding, you should get the patient checked by the doctor.

    Sometimes the trauma can be light, as when a person digs in too hard to clean the nostrils. In that case, the bleeding stops spontaneously after a few minutes.

    A high fever may sometimes be accompanied by a nosebleed. Again, this is because of the nose having to adapt to the difference in temperatures of the body and the air outside. ENT surgeon says, "This is occasionally seen in typhoid cases where the temperature rises very high."

    When bleeding from the nose occurs, you should first prop up the patient. Don't let him lie flat. If you do that, the blood will rush back and enter the throat making him choke or cough, thus increasing the pressure on his blood vessels and forcing out more blood. "Sometimes the blood that is thus forced back goes into the stomach and the patient then vomits it out through the mouth," says ENT surgeon. "At such times, everyone panics because the patient has vomited blood. They don't realize he's merely throwing out what he has swallowed."

    Ideally the patient should be made to sit up; head bent over a bowl so that the blood can drip down from the nose. Pinch closed the nostrils, letting the patient breathe through his mouth. Often, this stops the bleeding. Or you could put an ice pack on the nose. To make the pack, put some crushed ice in a clean kerchief or cloth and pack it closely over the nose. Use crushed ice, not chunks, because it can be molded around the nose, and even pressure applied. If ice is not at hand, give the patient a freshly-cut onion, or crushed garlic pods, or ammonium bicarbonate, to smell. The strong odor will repulse his sense of smell, forcing the nostrils to contract, and this stops the bleeding.

    NOT SERIOUS

    Nosebleeds are generally not serious. "In a normal person, the bleeding stops on its own after about five minutes," says ENT surgeon. "That it lasts for a long time and that the flow is heavy are only impressions. What happens is that, in the absence of muscles in the nose, the tightly-packed blood vessels cannot contract. So the bleeding continues till clotting sets in. and that normally occurs in about five minutes. But if the bleeding does continue longer, don't panic. Pinch the nostrils or use an ice pack to stanch the flow, which will happen after a while provided there is no serious damage. even if the bleeding stops you should get the injury examined by an ENT specialist to preclude complications later. "

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    Source by Andy G

    Views: 1

  • 3 Ways Web Design Works to Help Your Business Grow

    3 Ways Web Design Works to Help Your Business Grow

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    As you know, web design and development affects your business and audience. It is the first thing they see concerning your business, so it ought to make a good impression. Below are three important aspects of web design:

    1. Makes the first impression

    Like I said, your website is the first thing a potential client sees before knowing your services and how your business works. Those first few seconds are essential in your business because they determines if a potential client would become a client or not. And, it also determines your bounce rate. Would the client leave the site almost immediately? Or would they stay and check your services out?

    An unappealing website or – God forbid – an outdated one would make your audience immediately bounce. This is because first impression matters. What they see first – your branding and website – matters a lot on your business. So you should always keep yourself and your business up to date on the latest technological trends and developments.

    2. Helps your SEO

    A great web design is beyond how great it looks or how easy it is to navigate. Although these two are important on their own, a great web design should also be SEO-friendly.

    A great way to stay on top of your game among your competition is SEO. Let SEO be integrated into your website design from scratch on a long-term basis, and watch as your website improves its rankings in search engines like Google or Bing.

    If you don’t know how to integrate SEO into your website, do not leave it for a latter period. Instead, get a professional web developer who knows what he/she is doing.

    3. Builds up the character for your company

    How your website looks and feels to your audience is how they perceive the customer service to be. For example, when you enter a company for the first time, several things happens. You get recognised as a potential client, and immediately get attended to by the receptionist. The receptionist further directs you to either the waiting room or the person in charge directly.

    If you get transferred to the waiting room, you would be given certain refreshments – like coffee or tea – depending on your preference. And when you finally meet the person who would handle your request, the manner at which he/she treats you, their character, is what makes you stay or leave.

    The same thing goes for websites. Your website tells a potential client how the character of the company is. So you have to ask yourself, is your website user-friendly? Natural? Welcoming? Easy to navigate through? And most importantly, is it SEO-friendly, so that more clients can find your business?

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    Source by Karina Popa

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  • Efficient Home Remedies to Cure Eczema

    Efficient Home Remedies to Cure Eczema

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    Are you one of the people who have fallen victim to Eczema? Do you happen to know any person who is suffering from this condition? Eczema is a type of skin disorder that causes the affected person to start getting skin redness, itchiness, flakiness and in some instances some people even start bleeding. This is a condition which mainly affects children but there are also some adults who fall victims as well. Eczema is a very irritating condition which tends to make people very uncomfortable. This is why it is important for one to try and ensure that they handle it as soon as possible.

    There are different cures that have been designed to deal with eczema and they come in the form of topical medicines and topical creams. The only problem with these treatments is that they all cost money and some people may not be in a position to afford them. The great news is that there are different types of efficient home remedies to cure Eczema out there. Here are some few examples of the Eczema cure options that exist.

    1. Water Treatment

    If you are one of those people who may not be comfortable using the topical creams or other forms of medication, you might find water quite useful. Place cold water in a compress then apply it onto the affected skin twice a day. This will help in soothing the itchiness on the infected areas. The water can also be used to make an anti-eczema solution when mixed with almond leaves.

    2. Take baths with mild cleansers

    You need to maintain high levels of hygiene when fighting Eczema. These can be attained by taking a proper bath up to twice a day to ensure that your skin stays free of any impurities and dirt. This can be done by using mild soaps or cleansers which can be used to clear toxins and dirt from the skin surface.

    3. Coconut Oil

    This is one of the efficient home remedies to cure Eczema. This is because it has the ability to maintain the suppleness and softness of the skin. You just need to apply it on the affected area of ​​the skin and it will ensure that your skin stays nourished. Avoid the commercial lotions because most of them end up harming your skin.

    4. Papaya Seeds

    Papaya is a good Eczema cure because it helps in reducing the skin itchiness. It is prepared by mashing the seeds then applying them over the area of ​​the skin that has eczema.

    5. Spearmint

    The spearmint can help in soothing the swelling and itchiness that is caused by Eczema. You need to make a juice from spearmint leaves then apply it on an infected area.

    6. Mudpack

    Mudpack is one of the good Eczema treatments that you can use at home. This is because of the soothing effect that it has on the face. It is also considered to be a form of facial spa. You just need to apply it directly over the affected area and you will feel the relief instantly.

    7. The Sun as a Vitamin D source

    Exposure to the sun can also help in killing the bacteria that cause Eczema. The sun is also a rich source of vitamin D.

    The good thing about using home remedies to cure Eczema is the fact that they are readily available and the fact that the ingredients are mostly natural, there are no side effects.

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    Source by Veronica Ayuste

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  • Everything You Need to Know About Holistic Doctors

    Everything You Need to Know About Holistic Doctors

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    Holistic medical doctors combine the modern scientific treatment with complementary or alternative medicine like massage, acupuncture and chiropractic. The holistic doctor looks at everything and then gives a pharmaceutical drug option as well as an alternative treatment that could include homeopathic remedy. Homeopathic treatment isn’t something many doctors and institutions embrace, but it is under the umbrella of holistic medicine.

    A holistic doctor will most often encourage some diagnostic testing like hormone levels and adrenal function. This is done so as to try and find if there are any underlying causes that have led to an imbalance. The whole person is considered in the whole healing process so as to have health at its optimal by having balance.

    The practitioners in this area are of the belief that a human has parts that are interdependent and when one isn’t working as it should, all the others are affected. This means that if there is any kind of imbalance regardless of the type, it affects the overall health to a great extent.

    A good example is a person suffering from migraines. If they decide to visit this kind of doctor, they may not work out with only medications. The doctor will take time to look at all the possible factors that could be causing the headaches. He will also search for any other health problems that could cause the migraines including personal problems, stress, sleep habits and even diet. Treatment can involve using drugs as well as modifications to one’s lifestyle to make sure that the headaches don’t recur.

    The principles

    Holistic medicine also believes that unconditional support and love are very powerful healers and that a person is actually responsible for their own wellbeing and health. Other principles are:

    • The patient isn’t a disease but a person
    • Everyone has got innate healing powers
    • Treatment should involve the fixing, of course not just dealing with the symptoms.
    • There is a need for a team approach for healing to be effective and it should involve the doctor and patient and should address all the different aspects of personal life of the patient using a wide range of practices in health care.

    Types of treatment

    Different treatment techniques are applied to help patients to be responsible and to achieve their optimal health. The approaches depend on the training of the practitioner and they can include:

    • Education regarding self-care and lifestyle changes so as to promote wellness, including spiritual counseling, relationship counseling, and psychotherapy and even exercise among many others.
    • Alternative and complementary therapies including naturopathy, massage therapy, homeopathy, chiropractic care and acupuncture. And so on
    • Surgical procedures and modern medicine.

    Where to find a holistic doctor?

    Holistic providers can include homeopathic doctors, chiropractors, Naturopathic doctors, osteopathy doctors and even medical doctors. There are different associations that can help you get in touch with such a doctor depending on where you are based. There are online lists that can help you in finding someone close to you.

    Don’t settle for the first person you find. This is a profession like others, meaning there are people who do a better job than others. A recommendation from, a trusted source like someone close to you or a health organization that is credible could be a great idea.

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    Source by Shalini Madhav

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  • Importance of Evidence-Based Complementary Medicine

    Importance of Evidence-Based Complementary Medicine

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    The modern-day world has many challenges and thus good health is one of the greatest blessings in today’s era. For example, a rich man with a bad health will always be unsatisfied and unhappy! “Health is Wealth”. Improving your health is an opportunity that shouldn’t be missed. It is a fact that your health affects all the aspects of your life, be it professional, or personal. Probably that is the reason why evidence-based complementary and alternative medicine came into existence!

    With increasing number of health-related apps and journals on the internet, you can now easily move towards a healthier lifestyle. Even the experts of medicine have admitted that the advice and products of work best when supplemented with a doctor’s standard care and supervision.

    As the famous proverb suggests, “Prevention is better than cure” and evidence-based complementary and alternative medicine helps you achieve this goal. So, here are a few benefits that you might get if you follow an integrative healthcare protocol:

    • It helps you in receiving specific treatment plans as per your physical requirements. As each individual has a unique body, it is not advisable to subscribe to a generalized treatment protocol. An effective biotyping assessment studies your inherited traits such as body frame, personality type, digestive capacity, metabolic activity, nutrigenomics, as well as environmental factors. In this way, it provides you with a personalized holistic Integrative healthcare medicine advice.
    • It aims at examining and treating all the aspects of physical as well as emotional components. It is proven that daily stress negatively affects your emotions, biology and genetics. All this further results in greater risks of several chronic diseases such as cancer and heart disease!
    • It offers a wide range of Natural Cure and Remedies so that you are not completely dependent on pharmaceuticals, many of which have side-effects. The food that you eat is one of the biggest reasons behind your healthy (or unhealthy) life! Following unhealthy food habits can result in an increase in the risk of heart conditions, high blood sugar, obesity, etc. So, what could be better than utilizing food as a medicine?
    • It focuses on the prevention of diseases before it even occurs. While conventional medicines are prescribed for a lifetime for chronic disease, alternative medicine examines the root causes of the disease. It also encourages the patients to focus on preventing a disease by eating healthy foods, exercise, meditation, etc.

    So, if you also wish to treat or prevent any disease with Natural Cure and Remedies, evidence-based complementary medicine is the key! After all, it’s never too late for improving your health.

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    Source by Luke Harper

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  • How to Think Like a Marketer

    How to Think Like a Marketer

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    Many people say they hate marketing. That’s usually because they think marketing is all about advertising and sales.

    Marketing is a process, not an event. It involves research, promotion, and distribution along with advertising and sales.

    Maybe the most important and most overlooked aspect of marketing is having the right marketing attitude or marketing mindset. Think like a marketer.

    When you have a marketing mindset, you ask how you can build brand awareness to help your target audience become familiar with your products and services, and you as well. Developing that know, like, and trust factor with your audience is key.

    As you develop a marketing mindset, ideas of how to meet marketing goals on a daily basis will come easily, but here are a few ways to get started:

    • Know Your Product & Service Inside Out: This may sound obvious but think about how many times we, as customers, have walked away from buying something because the person helping us couldn’t answer a few basic questions about their product or service.
    • Find Ways to Leverage Mistakes of Competitors: It’s easy to see what the competition is doing well but just as much (and sometimes even more) can be learned by observing what your competition is doing not so well. The Internet is saturated with career service companies, but what makes your career service better than your competitors? Do your homework. Where are they weak? What client needs are not being met and what can you do to step in and meet those needs?
    • Point Clients In Your Direction: Solve client problems. Point them to one of your services or products and emphasize the benefits, value, and results they can gain from it-being a solution to their problem.
    • The “Bottom Line” Isn’t Just About Money Coming In: Looking for ways to save is just as important as finding new revenue streams. Instead of just recording where the money is going, watch for places to save. When looking at those numbers is there a way that sales can be made more efficiently?
    • Every Client Interaction Is a Networking Opportunity: The word “networking” makes some people uncomfortable. But it doesn’t have to be about schmoozing or closing a sale. It’s simply having a conversation in an effort to build new relationships or strengthen current ones.

    “The aim of marketing is to know and understand the customer so well the product or service fits him and sells itself.”-Peter F. Drucker

    In business, everything ties into marketing in one way or form-what you wear, how you communicate (verbally and non-verbally), and what you do to attract, retain, and maintain client relationships. All of it affects or contributes to the profitability and success of your business.

    Thinking like a marketer is a way of ensuring your company’s longevity.

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    Source by Maria Hebda

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  • Guilt Is a Useless Emotion

    Guilt Is a Useless Emotion

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    I once read a poem in my doctor’s office that went something like this:

    If a child is raised in anger, he will feel anger.

    If a child is raised with guilt, he will feel guilty.

    If a child is raised with shame, he will feel shame.

    If a child is raised in love, he will feel love.

    Of course that is not the whole poem, but you get the point. At the time, the poem was just something to read while I waited. Today the meaning is very clear to me.

    There is no such thing as guilt, you can not go to the store and buy a pound or bag of guilt. It is a man made ego minded emotion this is detrimental to humans living to their full potential.

    It seems to me that women carry so much guilt, whether it stems from being a woman, or the way we raised our children, or for being/or wanting to be successful, to being a sexual human. Where did it all start? Why have we continued to pass this down to each new generations? Mostly we do it subconsciously, although I know there are times when it is used for our advantage in certain situations.

    Many moons ago the female Goddess energy was the ruler of the universe, it was honored and valued. Did guilt arise when we stopped tuning into that energy and were slowly overpowered by the male energy that has dominated the universe for so long? Was it because we stopped standing our ground and speaking our truth? Who knows were guilt originated. I am not saying it is a female only emotion, nor pointing fingers, my point is for this particular article only.

    Guilt has kept so many stuck in the same place for years. Why? Just like the poem says, it is passed down through the stories we were told by our parents, grand parents, teachers and role models. These stories were laced with limiting beliefs that blocked us from actually achieving our full potential in life. This useless emotion became a vicious circle that many are still trying to step out of, or don’t even realize they are in.

    You get a great idea that will make you lots of money. Then the guilt thinking comes in, you start to hear the old stories, you can’t make more money than your husband, men are supposed to support the family. You may even see pictures of the people telling the story. OR, even worse, you want to express your sexuality, or your sexual energy and you hear that voice saying “good girls don’t” Well guess what, good girls do, and they have been for years. Even those catholic girls in high school that swore they didn’t. They do. We are human, we don’t need to feel guilty about anything. Especially expressing our true selves.

    Everyone makes mistakes in life, everyone, but we don’t have to feel guilty about it and carry it with us the rest of our lives. It is time to free ourselves of the past, to free ourselves of the guilt. It is time to forgive ourselves for allowing this to control any part of our lives.

    Guilt is an emotion that comes from fear based thinking. If we take a really good look at why we feel guilty for any particular situation, we will probably find that the thought process is not even our own. It was something passed down to us from someone else. And to think that is ruling our days!!

    Fortunately there is good news. The choice is ours as to whether we are going to carry the guilt or let it go. Give a moment to think how you would feel if you decided right this moment to let go of it. How would it feel to have put it out with the garbage on Monday morning? How does it feel? Light? Airy? Expansive? Free? Now ask yourself this. How often do you put the garbage out at the road, and then walk out and bring it back into the house? Never, Right? The same needs to happen when letting go of guilt, once you put it out, leave it out. In fact don’t even go back to smell it.

    How can we release guilt? Here are a few steps, these require you to love yourself enough to give yourself permission to feel good.

    1. Write out what you feel guilty about and why. Take one situation at a time. Write adamantly, don’t hold back on anything, just let it all go, allow the emotions to flow. Once you are done, set it down for a few moments, then go back and write a little more. Don’t read it over, tear it up, or burn it. As you do repeat ” I now choose to let this go, it no longer affects my life.”

    2. Sit with a situation in mind. Allow yourself to feel how you feel about it, visualize it, hear the stories other people told you about the situation. Feel where you feel this in your body. Ask yourself if the guilt is yours or someone else’s? When you have sat with it as long as you can, allow yourself to let it go. Visualize it leaving your body, feel it leaving your body and say I choose to let this go. I no longer need this in my life. I let it go in exchange for peace.

    3. Change the story you are telling yourself. When you catch yourself telling the guilt story either to yourself or someone else, catch it, don’t judge it, just change it to something possible, with positive emotions. Be aware of the thoughts and stories you tell, after all we get to choose them, they might as well be positive.

    4. Train your mind to look for thing to be grateful for. You will always find what you are look for, again it might as well be positive.

    In doing these exercises you will release the emotional charge the thoughts and feelings have on you. The memories may come back from time to time, but the emotions will not take hold of you, they will not control you. Quilt really is a useless emotion, with a choice attached. I choose to let it go so I can soar through the rest of my life free as a bird. Free yourself.

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    Source by Jenn Prothero

    Views: 0

  • How Your Focus AFFECTS Your Health?

    How Your Focus AFFECTS Your Health?

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    You are what you think! This adage, is extremely relevant, to our overall health, and well – being. Whether one pursues, the best possible course of action, or focuses, on the negative possibilities, often AFFECTS whether we are truly, happy, and healthy, or, let our personal negative thoughts, dominate us, or, whether, we consistently, are ready, willing, and able, to focus on, being, happier, and healthier. Henry Ford has been credited with saying, You can think you can, or can’t. Either way, you’ll be correct. With that in mind, this article will attempt to, briefly, consider, examine, review, and discuss, using the mnemonic approach, what this means, and represents, and why it’s such an essential consideration.

    1. Attitude; attention; actions: Do you proceed, with a true, positive, can – do, attitude, or, do you let the self – imposed limitations of your comfort zone, dominate you? How much attention do you pay, to your health, and well – being, and do your actions, match your rhetoric, and claims? Will you transform obstacles to challenges, to overcome, or consider them, as problems, and become debilitated?

    2. Faith; feeling; feelings: How much faith, do you have, in yourself? Are you feeling, good vibes, about your personal value, and do you pay close attention, to your feelings?

    3. Furnish; fruition; future: How might you furnish, the necessities, which make you, better, happier, more self – confident, prepared, and, thus, potentially, healthier? Will you have the persistence, to bring your finest efforts, to fruition? What might you be willing to do, today, to ensure a finer future?

    4. Energy; emphasis; endurance; expectations; excellence: Will you maintain an energy level, which enriches your existence? Will you place most of your emphasis, where it benefits you? Hopefully, you will realize, good things take time, and persistence, and will proceed with the endurance, to ensure positive results! When you demand the utmost degree of personal excellence, you will proceed with positive expectations, and self – belief!

    5. Character; create/ creative; consider: How will you create, your level of quality character, which ensures, a happier, healthier future? Creative individuals creatively consider, viable options and alternatives, in a well – considered manner!

    6. Time – tested; timely: In order to become happier, and healthier, there is no need, to reinvent the wheel! Therefore, it is beneficial, to learn, from the past, and proceed, with time – tested ways. However, unless/ until, you avoid procrastination, and proceed in a well – considered, timely manner, you will never, become, the best, you can possibly be!

    7. Strengths; stronger; solutions; spirit: Know your personal strengths, and weaknesses, effectively using areas of strength, while addressing any weakness! When you become stronger, and proceed, with a positive, productive, spirit, you will use quality, viable solutions, to ensure the finest possibilities!

    When you know, and understand, your personal responsibility, and how your focus, AFFECTS your possibilities, you enhance the chances of being happier, and healthier! Will you become, your own, best friend?

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    Source by Richard Brody

    Views: 0

  • Massive proportion of world’s population are living with herpes infection

    Massive proportion of world’s population are living with herpes infection

    Virus causing genital herpes may put millions of people at greater risk of infection with HIV

    About half a billion people worldwide are living with genital herpes, and several billion have an oral herpes infection, new estimates show.

    Authored by staff at the University of Bristol, World Health Organization (WHO), and Weill Cornell Medical College-Qatar, and published in the Bulletin of the World Health Organization,
    the new study estimates the global infection prevalence and incidence of herpes simplex virus types 1 and 2 (HSV-1 and HSV-2) in 2016. 

    “Herpes infection affects millions of people across the globe and can have far-reaching health effects. We need more investment and commitment to develop better treatment and prevention tools for this infection.” says Dr Sami Gottlieb, Medical
    Officer at WHO and an author of the study.

    Prevalence and incidence

    An estimated 491.5 million people were living with HSV-2 infection in 2016, equivalent to 13.2% of the world’s population aged 15 to 49 years. HSV-2 is almost exclusively sexually transmitted, causing infection in the genital or anal area (genital
    herpes).

    An estimated 3.7 billion people had HSV-1 infection during the same year – around 66.6% of the world’s population aged 0 to 49. HSV-1 is mainly transmitted by oral to oral contact to cause infection in or around the mouth (oral herpes). However,
    HSV-1 can also be transmitted to the genital area through oral-genital contact – during oral sex – to cause genital herpes. Most HSV-1 infections were oral; however, between 122 million to 192 million people were estimated to have genital
    HSV-1 infection, depending on the assumptions used in the estimation model.

    Because herpes is a lifelong infection, estimated prevalence increased with age; HSV-2 prevalence was also higher among women and in the WHO African Region.

    Health and social impacts

    Most people living with herpes, caused by either HSV-1 or 2, are unaware they have the infection.

    When symptoms do occur however, oral herpes infection can lead to painful sores around the mouth (“cold sores”). Genital herpes infection can cause recurring, often painful, genital sores, often referred to as genital ulcer disease. 

    WHO and partners published a study in March 2020 estimating that around 5% of the world’s population (187 million people) suffered from at least one episode of herpes-related genital ulcer disease in 2016 (1). Most of these episodes were due to
    HSV-2, which can recur frequently over many years.

    Recurrent symptoms of genital herpes can lead to stigma and psychological distress, and can have an important impact on quality of life and sexual relationships. However, in time, most people with herpes adjust to living with the infection.

    “Genital herpes is a substantial health concern worldwide – beyond the potential pain and discomfort suffered by people living with the infection, the associated social consequences can have a profound effect on sexual and reproductive health”
    says Dr Ian Askew, Director of the Department of Sexual and Reproductive Health and Research at WHO. 

    Herpes and HIV

    A strong association exists between HSV-2 infection and HIV infection. In 2019, WHO commissioned a modeling study to estimate how much HSV-2 infection might contribute to HIV incidence. The study estimated that almost 30% of new sexually acquired HIV
    infections in 2016 worldwide were likely attributable to HSV-2 infection (2). 

    Evidence shows that people with HSV-2 infection are at least three times more likely to become infected with HIV, if exposed. HSV-2 leads to inflammation and small breaks in the genital and anal skin that can make it easier for HIV to cause infection.
    In addition, people with both HIV and HSV-2 infection are more likely to spread HIV to others.

    Women have higher biologic susceptibility to both HSV-2 and HIV. Women living in the WHO Africa Region have the highest HSV-2 prevalence and exposure to HIV – putting them at greatest risk of HIV infection, with negative implications for their health
    and well-being. 

    For people living with HIV (or who are living with other conditions that compromise their immune systems) as well as HSV-2, the symptoms of herpes can be more severe and more frequent. 

    Neonatal herpes

    Neonatal herpes can occur when an infant is exposed to HSV in the genital tract during delivery. This is a rare condition, occurring in an estimated 10 out of every 100,000 births globally, but can lead to lasting neurologic disability or death. The risk
    for neonatal herpes is greatest when a mother acquires HSV infection for the first time in late pregnancy. Women who have genital herpes before they become pregnant are at very low risk of transmitting HSV to their infants.

    No cure – better treatment and prevention needed

    There is no cure for herpes. At present, antiviral medications, such as acyclovir, famciclovir, and valacyclovir, can help to reduce the severity and frequency of symptoms but cannot cure the infection.

    As well as increasing awareness about HSV infection and its symptoms, improved access to antiviral medications and heightened HIV prevention efforts for those with genital HSV symptoms are needed globally. 

    In addition, development of better treatment and prevention interventions is needed, particularly HSV vaccines. WHO and partners are working to accelerate research to develop new strategies for prevention and control of HSV infections. Such research includes
    the development of HSV vaccines and topical microbicides. Several candidate vaccines and microbicides are currently being studied.

    “A vaccine against HSV infection would not only help to promote and protect the health and well-being of millions of people, particularly women, worldwide – it could also potentially have an impact on slowing the spread of HIV, if developed
    and provided alongside other HIV prevention strategies” says Dr Meg Doherty, Director of the WHO Department of Global HIV, Hepatitis, and STI Programmes.

    Related publications

    WHO guidelines for the treatment of Genital Herpes Simplex Virus

    WHO preferred product characteristics for herpes simplex virus vaccines

     

    ———————-

    (1) Looker KJ, Johnston C, Welton NJ, et al. The global and regional burden of genital ulcer disease due to herpes simplex virus: a natural history modelling study. BMJ Glob Health. 2020;5(3):e001875. doi: 10.1136/bmjgh-2019- 001875.

    (2) Looker KJ, Welton NJ, Sabin KM, et al.Global and regional estimates of the contribution of herpes simplex virus type 2 infection to HIV incidence: a population attributable fraction analysis using published epidemiological data. Lancet Infect Dis.2020;20(2):240-249. doi: 10.1016/S1473-3099(19)30470-0.

    Massive proportion of world’s population are living with herpes infection
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  • New estimates highlight need to step up the response to hepatitis D

    Lyon, France, 29 April 2020 – In a study published in the Journal of Hepatology, 1 Professor Anna Maria Geretti and Dr Alexander Stockdale from the University of Liverpool (United Kingdom), in collaboration with researchers
    from the World Health Organization (WHO) and the International Agency for Research on Cancer (IARC), estimate that worldwide, hepatitis D virus (HDV) affects nearly 5% of people who have a chronic infection with hepatitis B virus (HBV) and that HDV
    co-infection could explain about 1 in 5 cases of liver disease and liver cancer in people with HBV infection..

    To map the epidemiology of HDV infection in the world, Professor Geretti and Dr Stockdale joined forces with the WHO Global Hepatitis Programme and IARC, alongside investigators in Germany, Malawi, and the United Kingdom. “Infection with HDV occurs
    in about 1 in 22 cases of chronic HBV infection in the world,” Dr Stockdale says. “More high-quality data are needed, but we have identified several geographical hotspots of high prevalence of HDV infection: in Mongolia, the Republic of
    Moldova, and countries in Western and Middle Africa.”

    “Although it is less common than hepatitis B, hepatitis D is a serious disease that often affects underprivileged and vulnerable populations,” says Dr Meg Doherty, Director of the WHO Global Hepatitis Programme. Those who are more likely to
    have HBV and HDV co-infection include people who inject drugs and people with hepatitis C virus or HIV infection. The risk of co-infection also appears to be higher in recipients of haemodialysis, men who have sex with men, and commercial sex workers.
    Dr Doherty points out, “This information helps in identifying the groups with HBV among whom we should be looking for HDV.”

    HDV (formerly known as the Delta agent) is a small virus – one of the smallest that is known to cause disease in humans – and can replicate only in the presence of HBV, from which HDV borrows some of its structures. Compared with people with
    HBV infection alone, those who have a chronic infection with both HBV and HDV have a much higher risk of developing disease in the form of cirrhosis and liver cancer. “HDV is a significant contributor to severe liver disease and liver cancer,”
    says IARC scientist Dr Catherine de Martel. “The findings from this study inform our work on the association between viral infections and cancer, which is focused on developing improved prevention strategies.”

    Professor Geretti concludes, “HDV has long been neglected, because for decades the prevalence of infection remained uncertain and effective treatment was lacking. Mapping the epidemiology of the infection is just the first step. More efforts are
    needed to reduce the global burden of chronic hepatitis B and develop medicines that are safe and effective against hepatitis D and are affordable enough to be deployed on a large scale to those who are most in need.”

    1 Stockdale AJ, Kreuels B, Henrion MYR, Giorgi E, Kyomuhangi I, de Martel C, Hutin Y, Geretti AM (2020). The global prevalence of hepatitis D virus infection: systematic review and meta-analysis. J Hepatol. Published online 23 April 2020;
    https://doi.org/10.1016/j.jhep.2020.04.008

    For more information, please contact

    Véronique Terrasse, Communications Group, at +33 (0)6 45 28 49 52 or terrassev@iarc.fr or IARC Communications, at com@iarc.fr

    The International Agency for Research on Cancer (IARC) is part of the World Health Organization. Its mission is to coordinate and conduct research on the causes of human cancer, the mechanisms of carcinogenesis, and to develop scientific strategies for
    cancer control. The Agency is involved in both epidemiological and laboratory research and disseminates scientific information through publications, meetings, courses, and fellowships. If you wish your name to be removed from our press release emailing
    list, please write to com@iarc.fr. 

    About University of Liverpool

    Founded in 1881 as the original ‘red brick’, the University of Liverpool is one of the UK’s leading research-intensive higher education institutions. Consistently ranked in the top 200 universities worldwide, we are a member of the prestigious
    Russell Group and have a global reach and influence that reflects our academic heritage as one of the country’s largest civic institutions. For more information please visit us at www.liverpool.ac.uk

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