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Journey of a Drug: Design to Market Seller
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Where do the medicines we take from chemists come from? How do the doctors know which drug is good for which disease? How the medicines really are able to cure a particular ailment they have been prescribed for? Do these questions come to your mind, whenever you buy any medicine?

Come, let us today know about the medicine development from the beginning …

The development of medicine is called a Clinical Research and has different Phases. Phases of the clinical research are the steps of experiments with a health intervention in an attempt to find enough evidence for a process which the scientists think would be helpful in medical treatment.

The pharmaceutical study starts its journey from a drug design and drug molecule discovery which further progresses into animal testing and then human studies to see the drug's effectiveness.

Drug undergoes many trials- Preclinical, Phase 0, Phase I, II, III and IV. Sometimes combined trials also are undertaken to reduce the time of development, like Phase I / II and II / III.

Pre-Clinical Study

When the drug molecule is identified, it undergoes many in vitro ( test tube or cell culture ) and in vivo ( animal ) experiments. These experiments are conducted to know the preliminary efficacy, toxicity, and pharmacokinetics of the various doses of the drug. Many drug molecules are designed at a time and these pre-clinical studies let the pharmaceutical companies decide which molecule has a greater potential in further studies.

Design of the Studies:

Trials are always conducted by following the set of steps, called the protocol, developed by the researchers to find the specific questions related to the medical product. Information from the prior studies become the base for the researchers to develop research questionnaire and objectives:
- Participant selection
- Number of participants
- Duration of the study
- Controlled or not
- How and what dosage will be given
- What and when the data will be collected
- Review and analysis time
Phase 0 Study

It is also called micro-dosing trials, 10-15 human subjects are taken and single sub-therapeutic doses are administered to gather the pharmacokinetic ( PK ) data of the drug. This enables the company in deciding to go or no go for the further development of the drug, based on more relevant human data instead of animal data.

Such trials exceed the speed of promising drug development by establishing whether or not the drug acts on humans as expected in pre-clinical studies.

After the company decides to take the molecule of the drug forward in development, it will have to submit the data of its preliminary studies to the FDA called Investigational New Drug ( IND ) application filing.

Phase I Study

Also called First-in-man studies as these are the first stage of human testing studies. These are the studies which are designed to determine the maximum dose that can be administered without showing adverse effects.

Contract Research Organizations ( CROs ) conduct such studies in the clinical trial clinics where medical staff provides full-time attention to 2-100 healthy subjects enrolled for the study and collects the data.

These studies determine the safety ( pharmacovigilance ), tolerability, pharmacokinetics ( PK ) and pharmacodynamics ( PD ) of the drug. The design of Phase I studies is dose-ranging also called dose escalation studies conducted in controlled clinics called Central Pharmacological Units ( CPUs ).

Usually, healthy subjects are hired but sometimes terminally ill patients like of cancer and HIV and also those who have already tried and failed to improve on existing medications.

There are two divisions for Phase I study:

Phase Ia: Single ascending dose

Phase Ib: Multiple ascending dose

Phase II Study

More than 100 diseased subjects are enrolled for a longer period study, to know the benefits of the drug along with its safety which includes genetic testing. These studies are also called as "Proof of Concept or Pilot" studies.

This is the phase when the drug's development can fail due to toxicity or less than expected results.

Two divisions of this phase are:

Phase IIa: Pilot study, to determine the clinical efficacy or the biological activity.

Phase IIb: Dose-finding study, to check the biological activity with minimal side-effects.

A combined trial determining the efficacy as well as toxicity are Phase I / II trials.

Phase III Study

These are pre-registration trials means the data of this study is submitted to the regulatory agency through New Drug Application (NDA) for its registration. Also called Pre-marketing or Pivotal trials.

Such studies are multicentral, randomized, in large diseased population ( more than 500 ) with much longer duration of treatment and short follow up period, to determine the long-term safety and efficacy of the drug.

Even if the regulatory submission is pending, the drug is received by the patients in case it's a lifesaving drug until the drug can be purchased.

'Label expansion' that is drug can treat an additional disease, other than the disease for which the drug is already approved, may also be the reason for running the Phase III trial.

It is said that for FDA ( United States Food and Drug Administration ) and MHRA ( United Kingdom's Medicines and Health products Regulatory Agency ) needs at least two trials of successful trials data to register the drug.

After these trials, the drug is approved for market selling.

Phase IV Study

These are Post Market Safety Monitoring studies done after the drug is registered. Also called Late Phase or Confirmatory trials.

This kind of study determines the long-term adverse effects on the much larger population for a very long duration (at least 2 years). If harmful effects are detected in this study, then the drug is disapproved and the company has to retrieve the drug from the market as it can no longer be sold.

The entire journey of the drug from a molecule to a market selling product takes around 15-20 years.

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Source by Nidhi Sharma

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July 27, 2022
Sports Medicine

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Despite what the name implies, sports medicine is not confined to the athletic field. The branch of orthopedics consists of the treatment of injuries resulting from physical activity. These injuries can occur due to overuse, over-exertion, traumatic collision, or over-extension of the ligaments and cartilage of joints. Sports injuries can occur to any part of the body; however, the majority of sports injuries occur in the major joints, including the shoulder, hip, knee, and ankle.

Minimally Invasive Rotator Cuff Surgery

A common sports-associated injury of the shoulder is a rotator cuff tear. Composed of a group of four different muscles and tendons, the rotator cuff coordinates the movement of the arm at the shoulder. A tear of these muscles due to a traumatic impact, repetitive motion, or a strong pull may result in serious pain and the loss of mobility in the shoulder.

Based on severity of the injury, a rotator cuff tear can be repaired through surgical or non-surgical methods. If pain is not relieved through non-surgical efforts and surgery is required, rotator cuff tears can be repaired through arthroscopic techniques. A minimally invasive procedure, arthroscopic surgery involves two small incisions for the insertion of a fiber-optic camera and specialized operating tools. Arthroscopic surgery usually results in the successful repair of the rotator cuff and an abbreviated and less painful recovery time.

ACL Repair Surgery for Knee Pain

A commonly performed sports medicine procedure is the repair of the anterior cruciate ligament (ACL) located within the knee. The ACL provides rotational stability to the knee and tears to the ligament occur due to over rotation, sudden changes in direction, landing incorrectly, or traumatic collision. Symptoms of an ACL tear include a 'popping' noise and the inability to put weight on the knee joint, followed by pain and swelling.
Non-surgical treatment options are available after an ACL tear; however, a torn ACL will not heal on its own and surgery is necessary to return to an active lifestyle. Advances in knee surgery techniques now allow a torn ACL to be repaired through an arthroscopic procedure. Arthroscopic surgery techniques allow for a faster recovery time, although an athlete will require at least six months before returning to sports.

Torn Meniscus Surgery for Knee Pain

The meniscus consists of two pieces of cartilage located between the thigh bone and the shinbone that act as cushioning and 'shock absorbers' between the two bones. Sports-related meniscal tears result from excess stress on the knee joint from traumatic collision, squatting, or over rotation, and often accompanies other knee injuries, such as an ACL tear.

Walking is still possible after a meniscal tear and athletes may continue to play through the injury. However, the knee will gradually become more stiff and swollen over a period of a few days. Non-surgical approaches to treatment include the RICE protocol of Rest, Ice, Compression, and Elevation. If the severity of the injury necessitates surgery, arthroscopic techniques utilizing a fiber-optic camera and miniature instruments will allow for the minimally invasive repair of the meniscus.

Shin Splint Repair

Shin splints are a common sports-related injury, as the condition results due to exercise-related overuse. Shin splints, or medial tibial stress syndrome, develop as repetitive, excessive physical activity causes muscle fatigue leading to extra force to be applied to the tissue attaching muscles to the shinbone.
Shin splints are treated with rest and a refrain from physical activity. Rarely do shin splints require surgery; however, persistent pain may indicate the development of multiple microfractures in the tibia. Microfractures are severe and may require the evaluation of a physician.

Achilles Tendon Repair Surgery

The Achilles tendon is the largest tendon in the body and connects the muscles in the back of the lower leg to the heel bone. The Achilles tendon is essential to mobility as it is used to walk, run, and jump. Tears can occur when the Achilles tendon is overstretched and cannot withstand the large forces exerted on it during physical activity. Pain and swelling accompany an Achilles tendon tear, as well as the inability to bend the foot downward.

Surgery is likely the only option to repair a completely torn Achilles tendon for patients who wish to return to sports. Surgically repaired Achilles tendons are more likely to return to near normal performance and less likely to be re-injured.

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Source by Blake Nonweiler

Views: 0

July 27, 2022
Can Hypnotherapy Cure Emetophobia?

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Emetophobia is a learnt behavioral response and for many people it can be a very debilitating condition. Unfortunately it’s a condition that is often misunderstood by a large number of people, including many medical professionals.

Emetophobia has elements of being both a phobia and an anxiety disorder. For many sufferers it’s something that they developed at a young again often in early childhood. It can develop from being sick themselves or from seeing someone else being sick, which understandably for a young child can be a very frightening experience.

The fear can also develop from the reaction of other people around them. I have had a large number of clients that developed the fear not because how they reacted to being sick but because of how a close family member panicked in response to someone being sick.

When we talk about curing Emetophobia what we are really talking about is overcoming the fear by changing how people perceive the situation. Many people would say that when the fear has gone they feel cured. In many cases hypnosis can be a very effective tool that enables people to overcome the fear of vomit.

While it is true that some people can overcome the fear of being sick just from hypnotherapy treatment alone in some cases however the hypnotherapy is not enough by itself. For those people they will need to deliberately get used to doings things differently based on what the therapist tells them they need to do to achieve freedom from the fear.

In the same way that if you go to a osteopath with a problem they may be able to correct the problem purely with what they do while you are on their treatment couch however in some cases that may not be enough by itself and in addition they will give you some form of therapeutic stretching or exercises to do.

If you are an Emetophobic or a relative / friend of an Emetophobic the first important thing you need to know is that in the majority of cases with the appropriate treatment / therapy the fear can be either significantly reduced or in many cases completely overcome.

The second thing you need to know is that while some people can overcome the fear relatively quickly for others it can take longer so you may need to be patient. No one therapy works for everyone in every situation. If the therapy / treatment you’re currently using isn’t working for you (you should be experiencing at least some improvement within a couple of appointments) then you may need to consider an alternative therapy route.

Being cured doesn’t mean you have to like being sick or the find the sound / smell pleasant. Being sick can be very unpleasant but it is normal to find the smell, sound and idea of it disgusting. No one likes being sick but that doesn’t mean you have to be afraid of it. Being cured means getting the response back to a normal and appropriate perspective, just like anyone else that has a normal response to being sick or vomiting. So you can be free from the fear.

Hypnotherapy has already helped many people to overcome fear of vomiting. You can overcome Emetophobia.

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Source by Paul A Wright

Views: 0

July 27, 2022
Flexible Yoga for Backbone Pain Relief and Overall Health
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Are you above 40 and thinking that developing hip flexibility or spinal flexibility at this age will not be possible? If yes, then read on. Hitting 40 is not an excuse to deprive yourself of good health, stamina and joint-pain free life you really deserve. However, what is important is to understand and choose something that works. Flexible yoga, as the name suggests is what you can try for back and hip flexibility, which is what keeps your overall fitness in good shape.

What is flexible yoga

As mentioned in one of our previous posts that yoga is not just a set of asanas or postures, flexible yoga is also not just about physical suppleness. However, we’ll keep the topic limited to physical flexibility for now. The basic idea behind flexible yoga is to develop suppleness in muscles and joints by using the most suitable set of asanas. As your spine becomes more flexible, you start gaining more stamina and overall better health.

Pashchimottasana to make your spine supple

It goes without saying that yoga as a whole is highly effective to control and cure many muscle and mind related issues. However, people have their own preferences in terms of choosing the right types of yogic postures, which are effective depending on individual needs. Personally, I like Pashchimottanasa to make and keep my spine flexible.

Yoga for spinal suppleness
- Surya Namaskar-Sun Salutation (12-step sequence)
- Chakrasana-Semi-circular pose
- Bhujangasana-Cobra pose
- Ustrasanana -Camel pose
- Paschimottansana-Forward bend
- Balasana-Child’s pose
- Shashankasana-Rabbit pose
- Halasana-Plough pose
- Sun salutation-surya namaskar
Developing flexibility easily

There are various other postures and variations of the above mentioned poses. It all depends upon what suits you and fits into your hectic daily schedule. Starting with easy postures such as child’s pose or cat cow pose, which can be done immediately after waking up while you are still in bed, are highly effective for beginners. You can move on to tougher postures as your spine starts becoming flexible.

Easy posture for spinal flexibility

Stretching is highly effective for suppleness of spine, muscles and other associated organs. You can start your day with a few stretching exercises such as cat cow pose. This is the easiest way to start making your spine flexible in addition to kick-starting your day actively and relieving your neck or back pain, if any.

Make your spine flexible effortlessly

We have covered Bhujangasana previously, but there is also a simple variation of this pose, which can be also be highly effective in keeping your backbone flexible, digestive system strong and neck pain-free. Simply lie flat on your stomach and lift your head and torso supported by your elbows. You need not stretch fully like you do while performing full Bhujangasana.

Natural Stretch -Benefits of semi-Bhujangasana
- No special equipment, place or time recommended.
- You can do this anytime except after meals
- You can also read, write or watch TV if this posture
- Keeps your digestive systems strong
- Reduces big belly and helps in overall weight loss
- Makes your spine supple without having to do specific set of exercises
- Relieves and prevents neck and back pain
- Relieves tiredness and fatigue immediately
- Positive state of mind
- Stretching in any form is one of the most effective ways to develop spinal flexiblity which is highly recommended for overall health.
Stretching is one of the most effective ways to develop spinal flexiblity which is highly recommended for overall health.

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Source by Felix Godwin

Views: 0
July 27, 2022
Women And Self-Confidence – Healing Women's Insecurity Issues Today

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Sound like a latte-in-the-sky dream? I mean the kind that could never happen in this lifetime?

Today, all that ends.

Let some new confidence with women understanding begin inside you, and beautiful begin being who you are to the core.

This program for women and self-confidence is exactly the kind of community of women friends you should meet. Its specialty is helping women exactly like you.

Heal those old wounds so you can break free from the past.

Stop feeling insecure and overwhelmed by other people's demands.

Pick up those shattered pieces of women's insecurity issues sitting around in your soul, heart and life and build something stunning and gorgeous with them.

It's like the Course in Miracles states, "Do not be afraid to look within you."

If you keep on beating yourself up OR ignoring it and hoping it will all solve itself, you can't pull yourself together.

Unleash the confident, Got-It-Together, GORGEOUS and RADIANT woman you were MEANT to BE.

There is nothing that feels better than having the total life confidence needed to be your real, luminous self.

It makes a woman undeniably gorgeous, and you don't have to be a super model here to be a confident woman.

It is life miracles of the highest order, and you deserve lots and lots of that!

Get YOUR life miraculously going again!

In a previous session I discussed other topics like how to realize more beauty and experience healthy weight loss without paying a fortune for a weight loss program.

And, imagine being able to turn the heads of men (AND women) as you walk into a room, radiating COMPLETE confidence and allowing your inner goddess to glow.

What if I told you that the universe is waiting to give you OCEANS of love?

Wave after wave of it!

A drenching, nourishing, sea of it!

You've built an emotional sea-wall that won't let it get to you, and here's the Truth:

Spark some sizzling hot romance EVEN if your relationship is flat-out boring right now (It takes mere SECONDS to put this to work for you …).

When you feel loved and confident

Don't deny your beautiful heart any longer. Unleash the miracle power of love in your life!

Yes, you can indeed change your love life and everything else, from PESSIMISTIC to PASSIONATE in a heartbeat.

You have what it takes to feel the POWER to go after your dreams, and you naturally ATTRACT the man of your dreams.

And if you're already in a relationship, you can build the kind of life together that most people only dream of.

Dating and relationships are so much easier (and fun!) Once you FINALLY start accepting love.

When you can FINALLY allow for to be given you love unapologetically from the world that's when your life and your relationships start to miraculously transform and you release all those women's insecurity issues.

Extend your inner beauty!

Begin right now in this instant to EFFORTLESSLY accept every kind of good and beautiful love into your life.

When women's insecurity issues have your life split apart in pieces all over the place, it's easy to feel defeated.

When frustration hooks up with unworthiness and they have a child called I AM SO TERRIBLY OVERWHELMED, confidence with women is difficult.

You know what I mean?

Wouldn't it be nice if you could let go of women's insecurity issues and get the JOY and BEAUTY of a woman who has her act together, as easily as ordering a latte with your BFF at your favorite coffee shop?

(Please note I always suggest searching the net for related material on how a woman with no dreams for the future can TODAY become a stronger confident woman.)

To your inner beauty shining forth!

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Source by James Nussbaumer

Views: 0

July 26, 2022
The Unique Power of Ayurveda to Heal Any Health Problem
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The amazing power of Ayurveda

What comes to our mind if we think about any types of treatment? It will obviously be allopathy or homeopathy. No wonder that Ayurveda secures no position in the list of the trustworthiness in the mind of many people. This Ayurveda has some kind of power which will go deep inside or in the root to eradicate any disease. This medication, from ancient time, is somehow overlooked or ignored by the users. The Ayurvedic Medicines exist or not we rarely bother! Things will get changed once you start believing it.

Ayurveda works if someone trusts

The young generation has a tendency to give a stare to these age-old medicines. They consider this type of medicine belongs to the pre-historic era. Ayurvedic treatment needs patience as well as time. All those who are in a hurry; this type of medicines will not be good for them. You can rely on Ayurveda if you enough time to use it regularly, without making any kind of mistakes. These Ayurvedic Medicines have no side effect. Yes, because of the main ingredients of this medicineor herbs. Taste-wise it will not be great of course. There are so many people who all have shown their faith in Ayurveda and got the desired result. You can be one of them easily. The biggest benefit of this Ayurveda is that it is not costly. Any and every kind of health related problems can easily be resolved by the touch of Ayurveda.

Why should you switch over to Ayurveda?
- A non-curable disease like Cancer and all can be cured by the power of herbs.
- Those who all are afraid of operations, this will be the greatest option for them. Ayurveda believes that surgery is the last step.
- Chronic diseases can easily get cured by Ayurveda medicines.
- These medicines are free from chemicals. That means no worry of side effects at all.
- Consumption of these types of medicines will cure the problem as well as develop the overall health condition by increasing the rate of metabolism, decrease the level of stress and bring back the obstinacy back into your life.
- These types of medicines will go to the root to eradicate the problem. That means that particular person will not suffer from the same problem again.
Availability of these Ayurveda medicines

Ayurvedic Medicines Manufacturers and dealers must be there in your locality also. Why don’t you visit one of those medicine shops and read out the compositions of these medicines by yourself to kick away all misconception regarding Ayurveda and its result? At that time only you will start believing in the magic of Ayurveda.

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Source by Samaria Thomas

Views: 0
July 26, 2022
Everything You Ever Wanted To Know About a Pain Doctor

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In all likeliness, you must have heard of the term ‘pain doctor’, otherwise also known as a pain specialist or even as a pain management specialist. Pain doctors help in managing pain and focus on pain medicine, which is all about preventing and treating different kinds of pain. Here are some of the things you need to know.

What Are the Qualifications of a Pain Doctor?

A pain doctor can be a medical doctor, also known as MD, or can be a doctor of osteopathy, specializing in pain medicine. Apart from treating pain-related disorders, they also treat symptoms that may have triggered pain. They also work with patients who have to deal with pain owing to a particular condition, such as post-operation related pain. In terms of services, many torment doctors have their clinics, where they offer comprehensive care for most pain-related conditions, or else, they may also work as consultants to healthcare providers and doctors. The role of pain doctors is an extensive one, where they offer counseling to patients, perform procedures as required, prescribe medicines and even offer emotional support. In a number of cases, where is caused due to a certain condition or diseases, the physician may refer the case to a pain management specialist, while keeping a check on the primary treatment. Apart from a medical degree, which is an obvious must, physicians are required to have a state license in the US.

What Are the Areas of Specialization?

torment management doctors can treat most conditions, not limited to back and neck torment, chronic torment, cancer torment, arthritis, reflex sympathetic dystrophy, pelvic torment, headaches, fibromyalgia, and orofacial torment. Many torment doctors are a part of different organizations, such as the American torment Society.

How Are Patients Treated?

Patients experience pain owing to a number of reasons, and therefore, the diagnosis and treatment also differs. Doctor usually suggest tests before starting off and may consider the family history of the patient, along with other relevant factors such as lifestyle and diet habits. Also, a detailed physical examination will be done to understand the pain conditions better. As for the treatments, the approach determines the next step. Some treatments are planned in a way that patients can live better, despite the pain, while others are more focused on reducing the extent of pain.

Common Treatments:

Pain doctors may use different kinds of treatments, such as injections in form of corticosteroids, and medications. Along with that, implantable devices such as stimulators are also used, besides physical therapy, surgery and trigger point injections. Lifestyle changes, meditation, hypnosis and relaxation are some of the other things that doctors may use to help a patient.

If you are suffering from chronic pain, consider seeing a pain doctor or ask your primary healthcare physician to offer help. The idea is to start treatment early, which may help in dealing with the symptoms better, and yes, do follow your doctor’s instructions for movements, actions and other things, especially if certain lifestyle changes can reduce your pain considerably.

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Source by Hampry Gomes

Views: 0

July 26, 2022
Drug Use – Advantages and Disadvantages

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Rampant, often unchecked use of drugs is a malaise that has been plaguing our society, and especially our younger generation for quite some time. It has grown quickly from a psychological bad malaise, a bad habit to a dangerous social evil, and in many countries, invite strict punitive action. Countries across the world try to combat this evil using combination’s of public awareness regarding the evils of drug use, severe clampdowns on drug usage/trafficking and penal impositions. However, this is still not enough as drug trafficking has proliferated across social strata, and is not limited to isolated groups of the society. So why exactly is drug usage considered to be one of the most debilitating and potentially dangerous of social evils?

One of the most primary reasons why consumption and business dealings on drugs are declared illegal internationally is because of the tremendous damage they cause to the human body. Drugs usually are of two kinds, and act as general nervous stimulants that can almost supercharge the brain and the nervous system for brief amounts of time. For that amount of time, the user has no sense of personal identity and this phase is usually described as a phase of euphoric detachment, while the user loses common consciousness. However, this effect is fleeting and does not last long. Drug-induced euphoria lasts for a very short time, usually culminating in sever hangovers and strains on the human body, which might manifest in physical and psychological reactions.

Drugs are generally hallucinogenic compounds that are primarily of two types, Organic and inorganic. Organic drugs are usually extracted from plants, and processed and consumed usually by burning them like tobacco. Inorganic compounds are much more difficult to obtain, as they are manufactured in pharmaceutical laboratories and are generally available in the form of tablets, pills and fluid solutions. Scientific studies have actually revealed that inorganic drugs/narcotic agents are more life-threatening and potentially debilitating in nature than their organic counterparts, even though prolonged drug use of either could result in serious consequences.

It might be said that drug use is actually dependent on more than one conditions and criterion. There are, in reality, numerous reasons that increase the usage of drugs within a particular demographic cross-section. These reasons could range from social, psychological, economical or just out of biological dependency. One reason why sustained usage of drug is deemed so dangerous to life and health is that it creates a sense of dependency within the user, who feels habituated by the use of drugs. Irrespective of the original stimulus, the consumption of drug becomes the primary objective in these cases, and the user often goes to extreme lengths to maintain the habit of drug use.

Presently, there are widespread efforts to contain if not eradicate drug use within a particular section of the society through governmental as well as non-governmental/individual efforts. General awareness, support groups, supportive rehabilitation centers and clinics that help drug abusers have now become popular, and much sought after to help individuals kick this habit.

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Source by Efti Babu

Views: 0

July 26, 2022
HOLISTIC Approach To Medicine

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Most people seek better health, but, often, their fear of going to the doctor, or needles, or taking certain medicines, and / or, their desire to avoid what they might consider the risks / side effects, associated with some convention treatments, become a risk to their personal health, and well – being. In the United States, our system of medical treatment is often referred to, as allopathic , which focuses on treating diseases, as opposed to preventive medicine. In many / most of the rest of the world, the emphasis is on reducing illnesses, by enhancing / improving our resistance, and / or immunity, and avoiding taking chemical medicines, initially, but only, when other approaches, aren't indicated. With that in mind, this article will attempt to briefly, consider, review, examine, and discuss, the HOLISTIC alternative / approach, using the mnemonic method.

1. Healing; homeopathy; heart / head: Holistic practitioners, often focus on healing the entire / whole person, including balancing the emotional and logical considerations, in a head / heart balance, without resorting, first, to merely treating symptoms. Most nations use homeopathic medicine, in a thorough, wellness program, as well as many other modalities.

2. Options: The focus is on taking advantage of all, viable options and alternatives, used together, towards creating better health!

3. Listen; learn: Wellness medicine treatment takes the time, to ask lots of questions, and listen carefully, in order to learn more, and be best positioned, to better health!

4. Importance; ideology; ideas; investigate: Utmost importance, in an alternative regimen, is possessing an ideology, of considering the bigger – picture, and take advantage of the finest relevant ideas / alternatives. When one investigates the options, and alternatives, he places himself, in the best position, for a potentially, healthier life, etc.

5. Systems; stronger; sustain: When one focuses on the best way to sustain our existence, and proceed, in a stronger way, he accepts alternative systems, focused on a healthier lifestyle!

6. Timely; trends: Pay attention to the discoveries, trends, and new alternative techniques, with the focus, on the best. most relevant alternatives, might create a healthier – you! In every medically – related, instance, it's essential to pursue, well – considered, timely actions and treatments, while ruling out major illnesses, such as cancer, etc.

7. Imagination; insist; improve: If you hope to improve your health, you will have to work, on it, while maintaining the imagination, to consider options and alternatives, and insist, on doing everything, possible, to enhance your well – being.

8. Care; caring; coordinate: Coordinate your care, and know, when allopathic approaches are needed, and necessary, and when, holistic approaches and techniques, might be best, for you! Happy people are generally, best – positioned, to be healthier, and are often, the most caring individuals.

Wise people don't ignore the possibilities, and are ready, willing and able, to consider, when HOLISTIC medicine and techniques, are best – suited, for you. Will you maintain the open – mind, to be the healthiest, you might possibly, become.

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Source by Richard Brody

Views: 0

July 26, 2022
Cure Stuttering Effectively With DAF And GILCU

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Stuttering as a speech disorder poses a lot of beliefs and theories concerning its origin and characteristics. One of them is the belief that stuttering is a result of the mismatch between a person's speech capacities and the demands the person receives from the environment. A person may constantly receive pressure around very fluent people. This may lead to the breakdown of his / her speech systems because the pressure he receives is just too much of what his speech system can accommodate. This makes concerned individuals look for ways on how to match these two factors and ways on how to cure stuttering.

There are a lot of myths and devices that promise instant cure for stuttering. Unfortunately, these are hoaxes and only provide temporary cure. But, with the help of techniques that are taught and implemented by certified speech pathologists, stutterers will be able to eliminate their moments of stuttering and communicate effectively. A lot of techniques are well-received by researchers in this field.

How To Cure Stuttering With GILCU?

Stutterers and concerned families have always been in the search for ways on how to cure stuttering. Speech pathologists incorporate different fluency techniques during therapies that promise to reduce and then completely eliminate the abnormal repetitions, prolongations and stoppages or blocks present in a stutterer's speech. With the help of the techniques, stutterers are also able to eliminate the physical concomitants or movements that they involuntarily do. Two of these techniques that aim to treat stuttering are Gradual Increase in Length and Utterance (GILCU) and Delayed Auditory Feedback (DAF).

How to cure stuttering with GILCU? GILCU, as what it stands for implies, involves the structured plan of the application of fluency techniques. The fluency techniques taught to patients are introduced and then applied in the patients' speech in a gradual manner. The patients will first apply the techniques with syllables then proceed with words, then to phrases and in turn to sentences. The patients, who seek ways of how to cure stuttering, will need to master first applying the techniques in the shortest utterances before proceeding to longer and more complex ones.

GILCU is incorporated in the Fluency Shaping treatment plan because it targets the over-all fluency of the person. This is also a convenient and effective technique because it doesn't bombard the stutterer with a lot of techniques at once. This gives the patient the chance to adapt and incorporate the techniques needed according to his / her own capacities. GILCU answers people over their concern on how to cure stuttering effectively.

How To Cure Stuttering With DAF?

DAF is another technique used by speech pathologists for people who are concerned on how to cure stuttering. Delayed Auditory Feedback, as the name implies, alters the auditory feedback system of the stutterer to lessen the dysfluencies. It is based on the belief that stutterers are not able to immediately implement corrections when what they wanted to say is different from what they have said. How to cure stuttering with DAF?

With DAF, a device is placed on the patient's ears. This device modifies the feedback system by delaying the sound heard by the stutterer by 50-75 milliseconds. This will make the stutterer prolong syllables and reduce the rate of utterances, thereby lessening the sudden dysfluencies created because of pressures for rapid speech. The delay caused by the DAF is decreased over the course of therapy to increase the pressure imposed on the stutterer. Its goal related to how to cure stuttering, is to practice the speaker to not hurry his / her speech and give him / her ample time to construct his ideas and produce them well.

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Source by Samuel Keith

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July 26, 2022